transforming growth factor, beta receptor II

同義遺伝子名

1110020H15Rik, AU042018, TGF-beta type II receptor, TGF-beta receptor type-2 precursor, TbetaRII, TGF-beta receptor type II, Tgfbr2, transforming growth factor, beta receptor II, RIIDN, TbetaR-II, DNIIR, TGFR-2

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:50.40

小脳:73.70

脳幹:-

脳梁:-

松果体:515.60

末梢神経:114.70

脊柱:-

網膜:-

目:76

動脈:84.40

静脈:-

リンパ節:32.40

末梢血:86.30

脾臓:171.20

胸腺:98.80

骨髄:115.40

脂肪:425.40

骨:613.70

皮膚:142.50

GeneChip

大脳:7.31

小脳:6.73

脳幹:-

脳梁:-

松果体:-

末梢神経:8.84

脊柱:7.51

網膜:6.99

目:7.97

動脈:-

静脈:11.23

リンパ節:12.05

末梢血:-

脾臓:11.49

胸腺:-

骨髄:9.50

脂肪:10.31

骨:10.05

皮膚:9.98

CAGE

大脳:2.71

小脳:-

脳幹:2.91

脳梁:-

松果体:-

末梢神経:-

脊柱:3.05

網膜:-

目:-

動脈:4.92

静脈:-

リンパ節:5.20

末梢血:-

脾臓:4.27

胸腺:4.03

骨髄:-

脂肪:-

骨:4.18

皮膚:4.74

RNA-seq

大脳:2.73

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:87.20

胎盤:55.20

前立腺:30.90

卵巣:-

精巣:22.20

心臓:55.80

骨格筋:284.10

食道:-

胃:229.10

腸:184.90

結腸:176.20

肝臓:27.20

肺:80.30

膀胱:264.70

腎臓:112.80

下垂体:206.70

甲状腺:112.50

副腎:-

膵臓:46.90

乳腺:163.20

唾液腺:216

GeneChip

子宮:11.55

胎盤:10.42

前立腺:10.29

卵巣:10.65

精巣:5.89

心臓:9.57

骨格筋:9.67

食道:-

胃:9.98

腸:9.69

結腸:-

肝臓:8.52

肺:11.70

膀胱:11.42

腎臓:9.44

下垂体:9.27

甲状腺:-

副腎:10.25

膵臓:8.44

乳腺:10.58

唾液腺:9.52

CAGE

子宮:4.91

胎盤:4.67

前立腺:3.08

卵巣:4.21

精巣:0

心臓:-

骨格筋:-

食道:-

胃:3.76

腸:3.46

結腸:3.63

肝臓:2.95

肺:5.18

膀胱:4.73

腎臓:-

下垂体:3.57

甲状腺:-

副腎:4.44

膵臓:3.16

乳腺:5.00

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:3.45

食道:-

胃:-

腸:-

結腸:-

肝臓:2.80

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_029575
Gene ID	21813
Unigene ID	Mm.172346
Probe set ID	1426397_at [Mouse430_2]
Ensembl ID	ENSMUSG00000032440

オーソログ対応遺伝子

ヒト[8]	NM_001024847, NM_003242
ラット[1]	NM_031132, NM_003242

染色体

遺伝子ファミリー (Interpro ID)

IPR000333	Activin type II receptor
IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR017194	Transforming growth factor-beta receptor, type II
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0032147	activation of protein kinase activity
GO:0006915	apoptosis
GO:0007420	brain development
GO:0060433	bronchus development
GO:0060434	bronchus morphogenesis
GO:0051216	cartilage development
GO:0030154	cell differentiation
GO:0007182	common-partner SMAD protein phosphorylation
GO:0048701	embryonic cranial skeleton morphogenesis
GO:0035162	embryonic hemopoiesis
GO:0007369	gastrulation
GO:0007507	heart development
GO:0001701	in utero embryonic development
GO:0006917	induction of apoptosis
GO:0002088	lens development in camera-type eye
GO:0030324	lung development
GO:0060463	lung lobe morphogenesis
GO:0060425	lung morphogenesis
GO:0060443	mammary gland morphogenesis
GO:0043011	myeloid dendritic cell differentiation
GO:0060044	negative regulation of cardiac muscle cell proliferation
GO:0008285	negative regulation of cell proliferation
GO:0009887	organ morphogenesis
GO:0060021	palate development
GO:0060389	pathway-restricted SMAD protein phosphorylation
GO:0001569	patterning of blood vessels
GO:0018105	peptidyl-serine phosphorylation
GO:0018107	peptidyl-threonine phosphorylation
GO:0016310	phosphorylation
GO:0002663	positive regulation of B cell tolerance induction
GO:0010634	positive regulation of epithelial cell migration
GO:0002053	positive regulation of mesenchymal cell proliferation
GO:0051138	positive regulation of NK T cell differentiation
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0002666	positive regulation of T cell tolerance induction
GO:0002651	positive regulation of tolerance induction to self antigen
GO:0006468	protein amino acid phosphorylation
GO:0006898	receptor-mediated endocytosis
GO:0042127	regulation of cell proliferation
GO:0040008	regulation of growth
GO:0070723	response to cholesterol
GO:0042493	response to drug
GO:0007224	smoothened signaling pathway
GO:0060440	trachea formation
GO:0060439	trachea morphogenesis
GO:0007179	transforming growth factor beta receptor signaling pathway
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0001570	vasculogenesis

Cellular Component

GO:0005901	caveola
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0045121	membrane raft
GO:0005886	plasma membrane
GO:0043235	receptor complex

Molecular Function

GO:0005524	ATP binding
GO:0005539	glycosaminoglycan binding
GO:0016301	kinase activity
GO:0046872	metal ion binding
GO:0031435	mitogen-activated protein kinase kinase kinase binding
GO:0000166	nucleotide binding
GO:0005515	protein binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0004872	receptor activity
GO:0004702	receptor signaling protein serine/threonine kinase activity
GO:0046332	SMAD binding
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0050431	transforming growth factor beta binding
GO:0005024	transforming growth factor beta receptor activity
GO:0005026	transforming growth factor beta receptor activity, type II
GO:0004675	transmembrane receptor protein serine/threonine kinase activity
GO:0034713	type I transforming growth factor beta receptor binding
GO:0034714	type III transforming growth factor beta receptor binding

transforming growth factor, beta receptor II

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function