toll-like receptor 4

Tlr4, lipopolysaccharide response, CD284 antigen, toll-like receptor 4, Toll-like receptor 4 precursor, Ly87, Rasl2-8, Lps, Ran/M1

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

Refseq ID	NM_021297
Gene ID	21898
Unigene ID	Mm.380491
Probe set ID	1418162_at [Mouse430_2]
Ensembl ID	ENSMUSG00000039005

ヒト[1]	NM_138554
ラット [0]

GO:0002218	activation of innate immune response
GO:0000187	activation of MAPK activity
GO:0007250	activation of NF-kappaB-inducing kinase activity
GO:0002322	B cell proliferation during immune response
GO:0071222	cellular response to lipopolysaccharide
GO:0071223	cellular response to lipoteichoic acid
GO:0042742	defense response to bacterium
GO:0050829	defense response to Gram-negative bacterium
GO:0032497	detection of lipopolysaccharide
GO:0007252	I-kappaB phosphorylation
GO:0006955	immune response
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0002758	innate immune response-activating signal transduction
GO:0032609	interferon-gamma production
GO:0060729	intestinal epithelial structure maintenance
GO:0006691	leukotriene metabolic process
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0042116	macrophage activation
GO:0045576	mast cell activation
GO:0002282	microglial cell activation during immune response
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0070373	negative regulation of ERK1 and ERK2 cascade
GO:0032689	negative regulation of interferon-gamma production
GO:0032700	negative regulation of interleukin-17 production
GO:0032707	negative regulation of interleukin-23 production
GO:0032715	negative regulation of interleukin-6 production
GO:0032720	negative regulation of tumor necrosis factor production
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity
GO:0043065	positive regulation of apoptosis
GO:0030890	positive regulation of B cell proliferation
GO:0032722	positive regulation of chemokine production
GO:0043388	positive regulation of DNA binding
GO:0070374	positive regulation of ERK1 and ERK2 cascade
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050729	positive regulation of inflammatory response
GO:0032727	positive regulation of interferon-alpha production
GO:0045359	positive regulation of interferon-beta biosynthetic process
GO:0032728	positive regulation of interferon-beta production
GO:0032729	positive regulation of interferon-gamma production
GO:0045362	positive regulation of interleukin-1 biosynthetic process
GO:0032732	positive regulation of interleukin-1 production
GO:0032733	positive regulation of interleukin-10 production
GO:0045084	positive regulation of interleukin-12 biosynthetic process
GO:0032735	positive regulation of interleukin-12 production
GO:0045368	positive regulation of interleukin-13 biosynthetic process
GO:0045410	positive regulation of interleukin-6 biosynthetic process
GO:0032755	positive regulation of interleukin-6 production
GO:0045416	positive regulation of interleukin-8 biosynthetic process
GO:0032757	positive regulation of interleukin-8 production
GO:0046330	positive regulation of JNK cascade
GO:0050671	positive regulation of lymphocyte proliferation
GO:0060907	positive regulation of macrophage cytokine production
GO:0045348	positive regulation of MHC class II biosynthetic process
GO:0042346	positive regulation of NF-kappaB import into nucleus
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process
GO:0070430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway
GO:0070434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0010572	positive regulation of platelet activation
GO:0032874	positive regulation of stress-activated MAPK cascade
GO:0051091	positive regulation of transcription factor activity
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
GO:0032760	positive regulation of tumor necrosis factor production
GO:0002537	production of nitric oxide during acute inflammatory response
GO:0050707	regulation of cytokine secretion
GO:0050727	regulation of inflammatory response
GO:0051930	regulation of sensory perception of pain
GO:0009617	response to bacterium
GO:0045471	response to ethanol
GO:0070542	response to fatty acid
GO:0032496	response to lipopolysaccharide
GO:0006979	response to oxidative stress
GO:0007165	signal transduction
GO:0034142	toll-like receptor 4 signaling pathway
GO:0002224	toll-like receptor signaling pathway

GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0046696	lipopolysaccharide receptor complex
GO:0016020	membrane
GO:0045121	membrane raft
GO:0048471	perinuclear region of cytoplasm
GO:0005886	plasma membrane

GO:0001530	lipopolysaccharide binding
GO:0001875	lipopolysaccharide receptor activity
GO:0043548	phosphoinositide 3-kinase binding
GO:0005515	protein binding
GO:0004872	receptor activity
GO:0004888	transmembrane receptor activity

toll-like receptor 4

発現データ

詳細情報

toll-like receptor 4

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function