CD40 antigen

詳細情報を見る

同義遺伝子名

CD40L receptor, CD40 antigen, CDw40, IMD3, AI326936, BP50, IGM, Tnfrsf5, Bp50, HIGM1, B-cell surface antigen CD40, Cd40, GP39

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:5.20 小脳:36.80 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:32.10 目:7.60 動脈:168.80 静脈:- リンパ節:64.80 末梢血:- 脾臓:1738 胸腺:29.60 骨髄:961.60 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:5.11 小脳:5.40 脳幹:- 脳梁:- 松果体:- 末梢神経:5.14 脊柱:5.54 網膜:4.79 目:5.19 動脈:- 静脈:5.65 リンパ節:8.90 末梢血:- 脾臓:8.76 胸腺:- 骨髄:6.78 脂肪:5.59 骨:6.21 皮膚:5.29
CAGE 大脳:0.22 小脳:- 脳幹:0.49 脳梁:- 松果体:- 末梢神経:- 脊柱:0.44 網膜:- 目:- 動脈:1.20 静脈:- リンパ節:3.60 末梢血:- 脾臓:2.27 胸腺:1.26 骨髄:- 脂肪:- 骨:0 皮膚:0.91
RNA-seq 大脳:0.93 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:18.60 骨格筋:- 食道:- 胃:- 腸:- 結腸:17.60     肝臓:-        肺:40.20    膀胱:- 腎臓:- 下垂体:- 甲状腺:112.50 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:5.60 胎盤:6.33 前立腺:5.22 卵巣:5.02 精巣:5.31 心臓:5.73 骨格筋:5.36 食道:- 胃:5.30 腸:5.40 結腸:- 肝臓:5.71 肺:6.81 膀胱:5.35 腎臓:5.39 下垂体:5.48 甲状腺:- 副腎:5.15 膵臓:6.20 乳腺:5.84 唾液腺:5.46
CAGE 子宮:1.41 胎盤:1.39 前立腺:0.20 卵巣:0.69 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0.67 腸:0.72 結腸:1.03     肝臓:0.64    肺:2.23 膀胱:0.86 腎臓:- 下垂体:0.70 甲状腺:- 副腎:0.78 膵臓:1.30 乳腺:0.74 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.67 食道:- 胃:- 腸:- 結腸:-     肝臓:0.50        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_011611
Gene ID 21939
Unigene ID Mm.271833
Probe set ID 1460415_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000017652

オーソログ対応遺伝子

ヒト[6]  NM_001250, NM_152854
ラット [0]  

染色体

遺伝子ファミリー (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1281194
1370315
1431091
7517360
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7519997
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24420080
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24709684

遺伝子オントロジー  (GO ID)

Biological Process

GO:0042113  B cell activation
GO:0006874  cellular calcium ion homeostasis
GO:0051607  defense response to virus
GO:0002768  immune response-regulating cell surface receptor signaling pathway
GO:0006954  inflammatory response
GO:0030890  positive regulation of B cell proliferation
GO:0043089  positive regulation of Cdc42 GTPase activity
GO:0032735  positive regulation of interleukin-12 production
GO:0048304  positive regulation of isotype switching to IgG isotypes
GO:0043406  positive regulation of MAP kinase activity
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0090037  positive regulation of protein kinase C signaling cascade
GO:0032855  positive regulation of Rac GTPase activity
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0042511  positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0050776  regulation of immune response
GO:0051023  regulation of immunoglobulin secretion

Cellular Component

GO:0009986  cell surface
GO:0009897  external side of plasma membrane
GO:0005576  extracellular region
GO:0005615  extracellular space
GO:0016021  integral to membrane
GO:0043231  intracellular membrane-bounded organelle
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0019899  enzyme binding
GO:0005515  protein binding
GO:0031625  ubiquitin protein ligase binding