TNF receptor-associated factor 2

詳細情報を見る

同義遺伝子名

AI325259, Tnf receptor-associated factor 2, TNF receptor-associated factor 2, Traf2

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:1.70 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:84.40 静脈:- リンパ節:10.80 末梢血:- 脾臓:39.50 胸腺:- 骨髄:12.80 脂肪:- 骨:- 皮膚:7.90
GeneChip 大脳:6.08 小脳:6 脳幹:- 脳梁:- 松果体:- 末梢神経:6.50 脊柱:6.32 網膜:6.73 目:6.44 動脈:- 静脈:6.55 リンパ節:8.33 末梢血:- 脾臓:8.49 胸腺:- 骨髄:7.43 脂肪:7.22 骨:7.04 皮膚:7.04
CAGE 大脳:1.77 小脳:- 脳幹:1.47 脳梁:- 松果体:- 末梢神経:- 脊柱:1.59 網膜:- 目:- 動脈:1.43 静脈:- リンパ節:2.54 末梢血:- 脾臓:2.52 胸腺:2.72 骨髄:- 脂肪:- 骨:2.66 皮膚:2.03
RNA-seq 大脳:2.16 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:30.90 卵巣:34.50 精巣:- 心臓:- 骨格筋:- 食道:- 胃:- 腸:37 結腸:-     肝臓:-        肺:30.10    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:9.40 乳腺:13.10 唾液腺:-
GeneChip 子宮:7.06 胎盤:6.87 前立腺:7.12 卵巣:7.17 精巣:7.63 心臓:6.91 骨格筋:7.56 食道:- 胃:7.16 腸:7.19 結腸:- 肝臓:6.87 肺:7.31 膀胱:6.98 腎臓:6.99 下垂体:6.74 甲状腺:- 副腎:7.28 膵臓:6 乳腺:7.51 唾液腺:7.25
CAGE 子宮:2.00 胎盤:1.95 前立腺:2.21 卵巣:2.02 精巣:1.89 心臓:- 骨格筋:- 食道:- 胃:1.75 腸:2.40 結腸:2.68     肝臓:2.38    肺:2.55 膀胱:2.29 腎臓:- 下垂体:2.10 甲状腺:- 副腎:2.35 膵臓:1.61 乳腺:2.43 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.39 食道:- 胃:- 腸:- 結腸:-     肝臓:2.04        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_009422
Gene ID 22030
Unigene ID Mm.339924
Probe set ID 1451233_at  [Mouse430_2]
Ensembl ID ENSMUSG00000026942

オーソログ対応遺伝子

ヒト[1]  NM_021138
ラット[1]  NM_001107815

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007250  activation of NF-kappaB-inducing kinase activity
GO:0006915  apoptosis
GO:0043623  cellular protein complex assembly
GO:0043066  negative regulation of apoptosis
GO:0034351  negative regulation of glial cell apoptosis
GO:0032743  positive regulation of interleukin-2 production
GO:0043507  positive regulation of JUN kinase activity
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0090073  positive regulation of protein homodimerization activity
GO:0002726  positive regulation of T cell cytokine production
GO:0051091  positive regulation of transcription factor activity
GO:0051865  protein autoubiquitination
GO:0030163  protein catabolic process
GO:0006461  protein complex assembly
GO:0051291  protein heterooligomerization
GO:0070207  protein homotrimerization
GO:0070534  protein K63-linked ubiquitination
GO:0042981  regulation of apoptosis
GO:0051023  regulation of immunoglobulin secretion
GO:0046328  regulation of JNK cascade
GO:0007165  signal transduction
GO:0033209  tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0005938  cell cortex
GO:0005737  cytoplasm
GO:0009898  internal side of plasma membrane
GO:0045121  membrane raft
GO:0043234  protein complex

Molecular Function

GO:0005174  CD40 receptor binding
GO:0019899  enzyme binding
GO:0042802  identical protein binding
GO:0016874  ligase activity
GO:0008289  lipid binding
GO:0046872  metal ion binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0019903  protein phosphatase binding
GO:0005102  receptor binding
GO:0046625  sphingolipid binding
GO:0031996  thioesterase binding
GO:0005164  tumor necrosis factor receptor binding
GO:0031625  ubiquitin protein ligase binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding