toll-like receptor 2

詳細情報を見る

Ly105, CD282 antigen, toll-like receptor 2, Tlr2, Toll-like receptor 2 precursor

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

Refseq ID	NM_011905
Gene ID	24088
Unigene ID	Mm.87596
Probe set ID	1419132_at [Mouse430_2]
Ensembl ID	ENSMUSG00000027995

ヒト[1]	NM_003264
ラット[1]	NM_198769

IPR004075	Interleukin-1 receptor, type I/Toll precursor
IPR000157	Toll-Interleukin receptor

GO:0002752	cell surface pattern recognition receptor signaling pathway
GO:0071221	cellular response to bacterial lipopeptide
GO:0071223	cellular response to lipoteichoic acid
GO:0071224	cellular response to peptidoglycan
GO:0042892	chloramphenicol transport
GO:0042742	defense response to bacterium
GO:0050830	defense response to Gram-positive bacterium
GO:0042496	detection of diacylated bacterial lipoprotein
GO:0042495	detection of triacylated bacterial lipoprotein
GO:0007252	I-kappaB phosphorylation
GO:0006955	immune response
GO:0052063	induction by symbiont of defense-related host nitric oxide production
GO:0006954	inflammatory response
GO:0045087	innate immune response
GO:0006691	leukotriene metabolic process
GO:0002282	microglial cell activation during immune response
GO:0002755	MyD88-dependent toll-like receptor signaling pathway
GO:0032289	myelin formation in the central nervous system
GO:0008285	negative regulation of cell proliferation
GO:0044130	negative regulation of growth of symbiont in host
GO:0032695	negative regulation of interleukin-12 production
GO:0032700	negative regulation of interleukin-17 production
GO:0046209	nitric oxide metabolic process
GO:0052033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immunity
GO:0032722	positive regulation of chemokine production
GO:0050715	positive regulation of cytokine secretion
GO:0050729	positive regulation of inflammatory response
GO:0032728	positive regulation of interferon-beta production
GO:0032733	positive regulation of interleukin-10 production
GO:0032735	positive regulation of interleukin-12 production
GO:0032741	positive regulation of interleukin-18 production
GO:0032755	positive regulation of interleukin-6 production
GO:0032757	positive regulation of interleukin-8 production
GO:0002687	positive regulation of leukocyte migration
GO:0060907	positive regulation of macrophage cytokine production
GO:0042346	positive regulation of NF-kappaB import into nucleus
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0045429	positive regulation of nitric oxide biosynthetic process
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process
GO:0048714	positive regulation of oligodendrocyte differentiation
GO:0034123	positive regulation of toll-like receptor signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0042535	positive regulation of tumor necrosis factor biosynthetic process
GO:0032760	positive regulation of tumor necrosis factor production
GO:0030177	positive regulation of Wnt receptor signaling pathway
GO:0050707	regulation of cytokine secretion
GO:0032493	response to bacterial lipoprotein
GO:0009617	response to bacterium
GO:0070542	response to fatty acid
GO:0002237	response to molecule of bacterial origin
GO:0002238	response to molecule of fungal origin
GO:0032494	response to peptidoglycan
GO:0007165	signal transduction
GO:0034134	toll-like receptor 2 signaling pathway
GO:0002224	toll-like receptor signaling pathway

GO:0042995	cell projection
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0031410	cytoplasmic vesicle
GO:0009897	external side of plasma membrane
GO:0016021	integral to membrane
GO:0016020	membrane
GO:0005886	plasma membrane

GO:0042498	diacylated lipoprotein binding
GO:0070891	lipoteichoic acid binding
GO:0008329	pattern recognition receptor activity
GO:0042834	peptidoglycan binding
GO:0005515	protein binding
GO:0046982	protein heterodimerization activity
GO:0004872	receptor activity
GO:0004888	transmembrane receptor activity
GO:0042497	triacylated lipoprotein binding

toll-like receptor 2

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function