mitogen-activated protein kinase kinase kinase 7

詳細情報を見る

同義遺伝子名

B430101B05, mitogen activated protein kinase kinase kinase 7, Transforming growth factor-beta-activated kinase 1, TGF-beta-activated kinase 1, Map3k7, TGF-beta activated kinase 1, transforming growth factor-beta-activated kinase 1, C87327, Mitogen-activated protein kinase kinase kinase 7, Tak1

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:57.30 小脳:73.70 脳幹:158.90 脳梁:- 松果体:257.80 末梢神経:57.30 脊柱:141.90 網膜:32.10 目:76 動脈:- 静脈:- リンパ節:21.60 末梢血:115 脾臓:- 胸腺:158.10 骨髄:- 脂肪:850.90 骨:112.70 皮膚:7.90
GeneChip 大脳:7.60 小脳:7.75 脳幹:- 脳梁:- 松果体:- 末梢神経:7.68 脊柱:7.67 網膜:6.38 目:6.25 動脈:- 静脈:8.13 リンパ節:8.43 末梢血:- 脾臓:8.20 胸腺:- 骨髄:8.78 脂肪:8.16 骨:8.25 皮膚:7.67
CAGE 大脳:3.15 小脳:- 脳幹:2.98 脳梁:- 松果体:- 末梢神経:- 脊柱:3.39 網膜:- 目:- 動脈:3.50 静脈:- リンパ節:3.59 末梢血:- 脾臓:3.16 胸腺:3.40 骨髄:- 脂肪:- 骨:3.32 皮膚:3.57
RNA-seq 大脳:3.12 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:27.60 前立腺:30.90 卵巣:11.50 精巣:36.90 心臓:- 骨格筋:71 食道:- 胃:- 腸:73.90 結腸:-     肝臓:9.10        肺:30.10    膀胱:- 腎臓:16.10 下垂体:90.40 甲状腺:- 副腎:848.90 膵臓:- 乳腺:55.50 唾液腺:-
GeneChip 子宮:7.89 胎盤:8.51 前立腺:7.78 卵巣:8.26 精巣:8.97 心臓:8.68 骨格筋:8.62 食道:- 胃:8.03 腸:8.15 結腸:- 肝臓:8.16 肺:7.65 膀胱:8.25 腎臓:8.34 下垂体:8.26 甲状腺:- 副腎:7.62 膵臓:7.94 乳腺:7.99 唾液腺:7.20
CAGE 子宮:3.14 胎盤:3.35 前立腺:3.02 卵巣:3.16 精巣:3.25 心臓:- 骨格筋:- 食道:- 胃:3.13 腸:3.01 結腸:3.02     肝臓:3.33    肺:3.31 膀胱:3.26 腎臓:- 下垂体:3.44 甲状腺:- 副腎:3.41 膵臓:3.41 乳腺:3.43 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:5.10 食道:- 胃:- 腸:- 結腸:-     肝臓:3.71        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_009316
Gene ID 26409
Unigene ID Mm.258589
Probe set ID 1425795_a_at  [Mouse430_2]
Ensembl ID ENSMUSG00000028284

オーソログ対応遺伝子

ヒト[16]  NM_003188, NM_145331, NM_145332, NM_145333
ラット[1]  NM_001107920, NM_145331, NM_145332, NM_145333

染色体

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遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8533096
10349636
10725249
10757786
10882101
10922068
11042159
11076861
11217851
11356033
11585904
12464436
12466851
12477932
12520002
12545162
12556533
12711537
12805214
12842894
12904583
14592977
14610273
15218018
15226265
15647289
15761153
15782199
15837794
15894542
15911626
16141072
16141073
16145668
16157589
16186825
16260493
16301747
16339560
16360132
16385569
16446357
16498455
16556914
16675448
16754690
16799562
16831874
16835226
16857737
16919269
16940043
17085580
17114649
17158449
17197697
17276978
17384642
17679097
17709393
17855357
17897957
17965022
17967808
18021073
18079694
18206350
18287559
18299321
18316610
18573910
18606667
18606807
18617512
18635759
18682563
18762249
18799693
18805969
18818394
18829460
18855897
18984593
19026643
19116914
19136967
19196865
19197243
19201899
19213760
19224920
19224984
19234607
19419968
19421137
19536134
19556242
19774455
19793892
19820695
19898473
19927120
19955178
20014292
20037141
20037161
20038579
20062539
20064449
20065289
20080763
20194509
20213696
20392264
20478530
20538596
20551513
20585657
20696287
20813258
20855879
20932476
20959492
21052097
21267068
21335610
21367917
21371434
21383695
21471444
21472480
21475303
21552285
21566132
21606198
21677750
21771792
21789165
21896478
21953618
21979919
21989986
22016814
22057290
22069318
22080947
22143887
22167179
22173278
22219364
22226633
22307082
22308391
22326956
22331902
22337877
22348103
22365665
22411628
22467172
22520462
22590573
22637723
22649194
22683931
22698400
22860133
22941947
22972987
23148225
23166301
23226465
23251462
23298137
23322300
23340735
23391818
23422957
23460641
23483698
23505428
23546880
23776175
23790753
23892723
23960234
23962979
23972991
23973329
23994637
24036998
24072697
24077561
24114841
24270572
24277938
24534530
24535827
24558484
24633226

遺伝子オントロジー  (GO ID)

Biological Process

GO:0000187  activation of MAPK activity
GO:0000186  activation of MAPKK activity
GO:0007250  activation of NF-kappaB-inducing kinase activity
GO:0001525  angiogenesis
GO:0006915  apoptosis
GO:0043966  histone H3 acetylation
GO:0007252  I-kappaB phosphorylation
GO:0007254  JNK cascade
GO:0000165  MAPKKK cascade
GO:0060546  negative regulation of necroptosis
GO:0001841  neural tube formation
GO:0016310  phosphorylation
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0032743  positive regulation of interleukin-2 production
GO:0046330  positive regulation of JNK cascade
GO:0043507  positive regulation of JUN kinase activity
GO:0002726  positive regulation of T cell cytokine production
GO:0006468  protein amino acid phosphorylation
GO:0006355  regulation of transcription, DNA-dependent
GO:0006950  response to stress
GO:0007165  signal transduction
GO:0051403  stress-activated MAPK cascade
GO:0006351  transcription, DNA-dependent
GO:0007179  transforming growth factor beta receptor signaling pathway

Cellular Component

GO:0005671  Ada2/Gcn5/Ada3 transcription activator complex
GO:0005737  cytoplasm
GO:0008385  IkappaB kinase complex
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0016301  kinase activity
GO:0000287  magnesium ion binding
GO:0004708  MAP kinase kinase activity
GO:0004709  MAP kinase kinase kinase activity
GO:0046872  metal ion binding
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups