mitogen-activated protein kinase 8

 詳細情報を見る

同義遺伝子名

Prkm8, JNK1, c-Jun N-terminal kinase 1, JNK, AI849689, Mapk8, Mitogen-activated protein kinase 8, Stress-activated protein kinase JNK1, mitogen activated protein kinase 8, c-Jun N-terminal kinase, SAPK1, Jnk1

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip 大脳:5.91 小脳:5.62 脳幹:- 脳梁:- 松果体:- 末梢神経:5.24 脊柱:5.76 網膜:5.19 目:5.28 動脈:- 静脈:5.40 リンパ節:5.22 末梢血:- 脾臓:5.68 胸腺:- 骨髄:5.32 脂肪:5.32 骨:5.48 皮膚:5.32
CAGE 大脳:4.18 小脳:- 脳幹:4.06 脳梁:- 松果体:- 末梢神経:- 脊柱:3.86 網膜:- 目:- 動脈:3.29 静脈:- リンパ節:3.68 末梢血:- 脾臓:2.90 胸腺:3.57 骨髄:- 脂肪:- 骨:3.02 皮膚:3.38
RNA-seq 大脳:8.07 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip 子宮:5.65 胎盤:5.99 前立腺:5.71 卵巣:5.54 精巣:7.44 心臓:5.77 骨格筋:6.09 食道:- 胃:5.57 腸:5.61 結腸:- 肝臓:5.28 肺:5.44 膀胱:5.23 腎臓:5.46 下垂体:5.42 甲状腺:- 副腎:5.50 膵臓:5.62 乳腺:5.67 唾液腺:5.29
CAGE 子宮:3.41 胎盤:3.39 前立腺:3.52 卵巣:3.59 精巣:4.10 心臓:- 骨格筋:- 食道:- 胃:2.16 腸:3.78 結腸:3.79     肝臓:3.12    肺:3.26 膀胱:3.12 腎臓:- 下垂体:3.27 甲状腺:- 副腎:3.09 膵臓:3.49 乳腺:3.30 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:4.44 食道:- 胃:- 腸:- 結腸:-     肝臓:2.52        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_016700
Gene ID 26419
Unigene ID -
Probe set ID 1420931_at  [Mouse430_2]
Ensembl ID ENSMUSG00000021936

オーソログ対応遺伝子

ヒト[8]  NM_002750, NM_139046, NM_139047, NM_139049
ラット[8]  NM_002750, NM_139046, NM_139047, NM_139049

染色体

-

遺伝子ファミリー (Interpro ID)

IPR008351  JNK MAP kinase
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

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遺伝子オントロジー  (GO ID)

Biological Process

GO:0048263  determination of dorsal identity
GO:0006954  inflammatory response
GO:0007254  JNK cascade
GO:0007258  JUN phosphorylation
GO:0043066  negative regulation of apoptosis
GO:0032091  negative regulation of protein binding
GO:0031175  neuron projection development
GO:0001503  ossification
GO:0018105  peptidyl-serine phosphorylation
GO:0018107  peptidyl-threonine phosphorylation
GO:0016310  phosphorylation
GO:0030335  positive regulation of cell migration
GO:0090045  positive regulation of deacetylase activity
GO:0045740  positive regulation of DNA replication
GO:0010628  positive regulation of gene expression
GO:0031116  positive regulation of microtubule polymerization
GO:0006468  protein amino acid phosphorylation
GO:0010468  regulation of gene expression
GO:0031063  regulation of histone deacetylation
GO:0032880  regulation of protein localization
GO:0006355  regulation of transcription, DNA-dependent
GO:0046686  response to cadmium ion
GO:0009408  response to heat
GO:0042542  response to hydrogen peroxide
GO:0006970  response to osmotic stress
GO:0009411  response to UV
GO:0007165  signal transduction

Cellular Component

GO:0033267  axon part
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0032839  dendrite cytoplasm
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0043204  perikaryon
GO:0031982  vesicle

Molecular Function

GO:0005524  ATP binding
GO:0042826  histone deacetylase binding
GO:0035033  histone deacetylase regulator activity
GO:0004705  JUN kinase activity
GO:0016301  kinase activity
GO:0004707  MAP kinase activity
GO:0000166  nucleotide binding
GO:0005515  protein binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups