adrenergic receptor kinase, beta 2

 詳細情報を見る

同義遺伝子名

GRK3, AW551196, beta ARK2, adrenergic receptor kinase, beta 2, AI851927, Adrbk-2, 4833444A01Rik, Adrbk2, Bark-2

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip nodata
CAGE 大脳:3.14 小脳:- 脳幹:2.75 脳梁:- 松果体:- 末梢神経:- 脊柱:2.54 網膜:- 目:- 動脈:2.50 静脈:- リンパ節:2.95 末梢血:- 脾臓:2.10 胸腺:1.35 骨髄:- 脂肪:- 骨:2.09 皮膚:1.67
RNA-seq 大脳:4.33 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip nodata
CAGE 子宮:2.14 胎盤:0.88 前立腺:2.00 卵巣:1.96 精巣:3.00 心臓:- 骨格筋:- 食道:- 胃:1.57 腸:0.72 結腸:1.77     肝臓:1.02    肺:2.61 膀胱:1.92 腎臓:- 下垂体:2.29 甲状腺:- 副腎:2.22 膵臓:0.84 乳腺:2.02 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:2.42 食道:- 胃:- 腸:- 結腸:-     肝臓:1.85        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_177078
Gene ID 320129
Unigene ID -
Probe set ID -
Ensembl ID ENSMUSG00000042249

オーソログ対応遺伝子

ヒト[1]  NM_005160
ラット[1]  NM_005160

染色体

5F  [113,339,498  -  113,444,811]

遺伝子ファミリー (Interpro ID)

IPR000961  AGC-kinase, C-terminal
IPR001849  Pleckstrin homology
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR000342  Regulator of G protein signalling
IPR016137  Regulator of G protein signalling superfamily
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

1869533
7761854
8035170
8638670
8889548
8917529
8955126
9325250
9345023
9365243
9802886
10198406
10338466
10349636
10922068
11042159
11076861
11217851
12466851
12794091
14610273
15140929
16141072
16141073
16602821
17344394
17698926
17959804
18165681
18554416
20534436
21267068
21677750
23935208

遺伝子オントロジー  (GO ID)

Biological Process

GO:0002029  desensitization of G-protein coupled receptor protein signaling pathway
GO:0043647  inositol phosphate metabolic process
GO:0006886  intracellular protein transport
GO:0016310  phosphorylation
GO:0001934  positive regulation of protein amino acid phosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0031623  receptor internalization
GO:0046154  rhodopsin metabolic process
GO:0007165  signal transduction

Cellular Component

GO:0030424  axon
GO:0005929  cilium
GO:0044441  cilium part
GO:0005829  cytosol
GO:0043198  dendritic shaft
GO:0043197  dendritic spine
GO:0016020  membrane
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0045202  synapse
GO:0030018  Z disc

Molecular Function

GO:0005524  ATP binding
GO:0047696  beta-adrenergic receptor kinase activity
GO:0031748  D1 dopamine receptor binding
GO:0004703  G-protein coupled receptor kinase activity
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0005543  phospholipid binding
GO:0004672  protein kinase activity
GO:0004674  protein serine/threonine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups