deleted in liver cancer 1

 詳細情報を見る

同義遺伝子名

Dlc-1, Stard12, Rho-GTPase-activating protein 7, Rho-type GTPase-activating protein 7, StARD12, START domain-containing protein 12, STARD12, Dlc1, p122-RhoGAP, Arhgap7, Deleted in liver cancer 1 protein homolog, StAR-related lipid transfer protein 12, HP, deleted in liver cancer 1

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:38.20 小脳:18.40 脳幹:- 脳梁:- 松果体:- 末梢神経:19.10 脊柱:- 網膜:32.10 目:30.40 動脈:253.20 静脈:- リンパ節:32.40 末梢血:- 脾臓:65.80 胸腺:- 骨髄:- 脂肪:425.40 骨:50.10 皮膚:-
GeneChip 大脳:4.80 小脳:5.46 脳幹:- 脳梁:- 松果体:- 末梢神経:4.55 脊柱:4.67 網膜:4.72 目:4.78 動脈:- 静脈:5.28 リンパ節:4.53 末梢血:- 脾臓:4.65 胸腺:- 骨髄:4.50 脂肪:6.19 骨:4.36 皮膚:4.79
CAGE nodata
RNA-seq 大脳:4.76 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:124.30 前立腺:- 卵巣:11.50 精巣:14.80 心臓:55.80 骨格筋:35.50 食道:- 胃:- 腸:- 結腸:-     肝臓:27.20        肺:70.30    膀胱:- 腎臓:40.30 下垂体:38.80 甲状腺:- 副腎:- 膵臓:9.40 乳腺:52.20 唾液腺:-
GeneChip 子宮:4.45 胎盤:5.78 前立腺:4.31 卵巣:5.09 精巣:4.63 心臓:5.52 骨格筋:4.97 食道:- 胃:4.68 腸:4.63 結腸:- 肝臓:5.42 肺:5.61 膀胱:4.92 腎臓:4.82 下垂体:4.67 甲状腺:- 副腎:4.82 膵臓:4.80 乳腺:5.29 唾液腺:4.66
CAGE nodata
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.28 食道:- 胃:- 腸:- 結腸:-     肝臓:3.49        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_015802
Gene ID 50768
Unigene ID Mm.210875
Probe set ID 1450206_at  [Mouse430_2]
Ensembl ID ENSMUSG00000031523

オーソログ対応遺伝子

ヒト[7]  NM_001164271, NM_006094, NM_024767, NM_182643
ラット[2]  NM_001127446, NM_006094, NM_024767, NM_182643

染色体

-

遺伝子ファミリー (Interpro ID)

IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP

Link to Pubmed  (Pubmed ID)

8889548
10349636
10702663
11042159
11076861
11217851
12034501
12040188
12466851
12477932
12520002
12904583
14610273
15710412
16141072
16141073
16919269
17967808
18519636
18799693
20199662
21267068
21677750
22792269
23010077

遺伝子オントロジー  (GO ID)

Biological Process

GO:0030036  actin cytoskeleton organization
GO:0006919  activation of caspase activity
GO:0007202  activation of phospholipase C activity
GO:0007010  cytoskeleton organization
GO:0048041  focal adhesion formation
GO:0030900  forebrain development
GO:0003007  heart morphogenesis
GO:0021575  hindbrain morphogenesis
GO:0006917  induction of apoptosis
GO:0030336  negative regulation of cell migration
GO:0008285  negative regulation of cell proliferation
GO:0035024  negative regulation of Rho protein signal transduction
GO:0051497  negative regulation of stress fiber formation
GO:0001843  neural tube closure
GO:0043547  positive regulation of GTPase activity
GO:0035307  positive regulation of protein amino acid dephosphorylation
GO:0032321  positive regulation of Rho GTPase activity
GO:0032956  regulation of actin cytoskeleton organization
GO:0008360  regulation of cell shape
GO:0007165  signal transduction

Cellular Component

GO:0005884  actin filament
GO:0005901  caveola
GO:0030054  cell junction
GO:0005737  cytoplasm
GO:0005925  focal adhesion
GO:0005622  intracellular
GO:0016020  membrane
GO:0045121  membrane raft
GO:0005634  nucleus
GO:0001725  stress fiber

Molecular Function

GO:0005096  GTPase activator activity
GO:0043274  phospholipase binding
GO:0005100  Rho GTPase activator activity
GO:0042169  SH2 domain binding
GO:0017166  vinculin binding