toll-like receptor 9

詳細情報を見る

同義遺伝子名

CD289 antigen, toll-like receptor 9, Toll-like receptor 9 precursor, Tlr9

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:- 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:43.20 末梢血:- 脾臓:39.50 胸腺:9.90 骨髄:- 脂肪:- 骨:- 皮膚:-
GeneChip 大脳:6.06 小脳:6.35 脳幹:- 脳梁:- 松果体:- 末梢神経:6.17 脊柱:6.42 網膜:6.41 目:6.75 動脈:- 静脈:6.47 リンパ節:6.23 末梢血:- 脾臓:6.49 胸腺:- 骨髄:6.21 脂肪:6.27 骨:6.34 皮膚:6.65
CAGE 大脳:1.19 小脳:- 脳幹:1.13 脳梁:- 松果体:- 末梢神経:- 脊柱:1.42 網膜:- 目:- 動脈:2.69 静脈:- リンパ節:5.85 末梢血:- 脾臓:4.05 胸腺:2.41 骨髄:- 脂肪:- 骨:3.06 皮膚:2.82
RNA-seq 大脳:0.64 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:7.40 心臓:- 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:9.10        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:3.30 唾液腺:-
GeneChip 子宮:6.08 胎盤:6.48 前立腺:5.98 卵巣:6.10 精巣:6.80 心臓:6.71 骨格筋:6.36 食道:- 胃:6.31 腸:6.12 結腸:- 肝臓:6.42 肺:6.18 膀胱:5.96 腎臓:6.15 下垂体:6.29 甲状腺:- 副腎:5.94 膵臓:6.88 乳腺:6.33 唾液腺:6.48
CAGE 子宮:2.28 胎盤:0.98 前立腺:0.93 卵巣:1.83 精巣:0 心臓:- 骨格筋:- 食道:- 胃:0.67 腸:1.60 結腸:1.52     肝臓:0.91    肺:2.76 膀胱:2.00 腎臓:- 下垂体:1.22 甲状腺:- 副腎:1.94 膵臓:0.84 乳腺:2.03 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:0.39 食道:- 胃:- 腸:- 結腸:-     肝臓:1.68        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

IDs

Refseq ID NM_031178
Gene ID 81897
Unigene ID Mm.44889
Probe set ID 1422083_at  [Mouse430_2]
Ensembl ID ENSMUSG00000045322

オーソログ対応遺伝子

ヒト[1]  NM_017442
ラット[1]  NM_017442

染色体

-

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

8889548
11130078
11470918
11812998
11867692
11923871
11947920
12193753
12244198
12356687
12408049
12466851
12515817
12538732
12626528
12626561
12630564
12759192
12875990
12900525
12902324
12935356
14563635
14607920
14657211
14716310
14734643
14736866
14762789
14976262
14978111
14993594
15128790
15197227
15210814
15272082
15345224
15356140
15373969
15534227
15538945
15630134
15634876
15634897
15650774
15654341
15671286
15678105
15709004
15765149
15767370
15778393
15922717
16027240
16034101
16039576
16047338
16059640
16081822
16142239
16143103
16148144
16204620
16219804
16230478
16244651
16260486
16272281
16272328
16301648
16301743
16325814
16341217
16365150
16413926
16415873
16421948
16440059
16458386
16461338
16492804
16554027
16554296
16585586
16602821
16604075
16612387
16650483
16670325
16703567
16741252
16751377
16751405
16798839
16818796
16840729
16878177
16886064
16896155
16906541
16926427
16951309
16954198
16973389
16982883
17004992
17030073
17038535
17082664
17085599
17114418
17114424
17117477
17118979
17128265
17135446
17170125
17177977
17202381
17227820
17229689
17277148
17325049
17331636
17339472
17339488
17353291
17360957
17371986
17389237
17404286
17404301
17404302
17417641
17452530
17456769
17462991
17464186
17469139
17473064
17474149
17485512
17488193
17521621
17548579
17570345
17572686
17579017
17599410
17646407
17686871
17705137
17705260
17713535
17725607
17785831
17804687
17853411
17875630
17878370
17913820
17918201
17925007
17939949
17942529
17947693
17950005
17982056
17984204
17992263
17998391
18025183
18034422
18060042
18086870
18097045
18097414
18166152
18178848
18183029
18194990
18203139
18239127
18250457
18250459
18256672
18266299
18273445
18276597
18288107
18305095
18305481
18322216
18332208
18342006
18354200
18378636
18378686
18394314
18398511
18406377
18423196
18424698
18426877
18474631
18480050
18480244
18513998
18552210
18559428
18565585
18606688
18614760
18624303
18641311
18641342
18641352
18664530
18684928
18691914
18760996
18776126
18794294
18802047
18817866
18820679
18835196
18922969
18931679
18936185
18941203
18950591
18974086
18981243
19009528
19019086
19050267
19050280
19075396
19088275
19109197
19120284
19122641
19144984
19155485
19164858
19200758
19200759
19201879
19228664
19265155
19297619
19299691
19299716
19332776
19362372
19382893
19414781
19414785
19433551
19451267
19494293
19528537
19535142
19535645
19551900
19553540
19561095
19567203
19574451
19576795
19585512
19587007
19587376
19587448
19596990
19648272
19657352
19687229
19720755
19758186
19767510
19786067
19797157
19834064
19841163
19846276
19874547
19879164
19890330
19913447
19918123
19923461
19923465
19923471
19933833
19933834
19942314
19944565
19995952
20005572
20007584
20011699
20042593
20049870
20051628
20089701
20093775
20107166
20107183
20114022
20114028
20145605
20174568
20187710
20200270
20200276
20200279
20205276
20228254
20231379
20231693
20308556
20347818
20360853
20393135
20400700
20427776
20431620
20432233
20442858
20451253
20451901
20466823
20483722
20483769
20488791
20495560
20526283
20577143
20581055
20610651
20660347
20660707
20668698
20696824
20739833
20804821
20810248
20847273
20847283
20864677
20865117
20865800
20876455
20937844
20966396
20974942
21045126
21059889
21078886
21098227
21115691
21115693
21116636
21127878
21132311
21190299
21239460
21239713
21273385
21278302
21282509
21287547
21300776
21311566
21368092
21435586
21439959
21458307
21474674
21482737
21497117
21515789
21525381
21525388
21538349
21538629
21544241
21547259
21559519
21567398
21571065
21592581
21603856
21604257
21609647
21625574
21666062
21683627
21685327
21687712
21690093
21690387
21698299
21721026
21762664
21765404
21766476
21788345
21801870
21808234
21820332
21829705
21835795
21844387
21849499
21859955
21860217
21911421
21940676
21947771
21960132
21982832
21987815
22031762
22036947
22039448
22078208
22078797
22085974
22096530
22104112
22114338
22156340
22170068
22171256
22184724
22205030
22205119
22207622
22227568
22250086
22258621
22297845
22306056
22311925
22323544
22342842
22422883
22442158
22453241
22505996
22508063
22516959
22544937
22553782
22574220
22611152
22628437
22634614
22635254
22653776
22659029
22662179
22666391
22677561
22693446
22706912
22718261
22719247
22745710
22777843
22777876
22795895
22816092
22821982
22822061
22826298
22832815
22837383
22844124
22893852
22896628
22902233
22908309
22915067
22940550
22962685
22970242
22988114
23008447
23010947
23028824
23034650
23043942
23071157
23110142
23142781
23180821
23189191
23219390
23241879
23290966
23296704
23296706
23313320
23325805
23357786
23370539
23372731
23382217
23439309
23467932
23479602
23497207
23548820
23584070
23585677
23600828
23630357
23650544
23673637
23686399
23752491
23778142
23893288
23913633
23935245
23936560
23956420
23966630
23967355
23993650
24023674
24038087
24041926
24042114
24154870
24169824
24170313
24184555
24249581
24342772
24353176
24353186
24387292
24436372
24474776
24478078
24514026
24516163
24534189
24634489
24637670
24711620
24719462
24742987

遺伝子オントロジー  (GO ID)

Biological Process

GO:0051607  defense response to virus
GO:0007252  I-kappaB phosphorylation
GO:0006955  immune response
GO:0006954  inflammatory response
GO:0045087  innate immune response
GO:0030277  maintenance of gastrointestinal epithelium
GO:0002755  MyD88-dependent toll-like receptor signaling pathway
GO:0032715  negative regulation of interleukin-6 production
GO:0032717  negative regulation of interleukin-8 production
GO:0032088  negative regulation of NF-kappaB transcription factor activity
GO:0034122  negative regulation of toll-like receptor signaling pathway
GO:0032722  positive regulation of chemokine production
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0050729  positive regulation of inflammatory response
GO:0045356  positive regulation of interferon-alpha biosynthetic process
GO:0045359  positive regulation of interferon-beta biosynthetic process
GO:0032728  positive regulation of interferon-beta production
GO:0045078  positive regulation of interferon-gamma biosynthetic process
GO:0032733  positive regulation of interleukin-10 production
GO:0032735  positive regulation of interleukin-12 production
GO:0032741  positive regulation of interleukin-18 production
GO:0032755  positive regulation of interleukin-6 production
GO:0032757  positive regulation of interleukin-8 production
GO:0043507  positive regulation of JUN kinase activity
GO:0042346  positive regulation of NF-kappaB import into nucleus
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0051770  positive regulation of nitric-oxide synthase biosynthetic process
GO:0034123  positive regulation of toll-like receptor signaling pathway
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0032760  positive regulation of tumor necrosis factor production
GO:0050707  regulation of cytokine secretion
GO:0050727  regulation of inflammatory response
GO:0002237  response to molecule of bacterial origin
GO:0009615  response to virus
GO:0007165  signal transduction
GO:0034162  toll-like receptor 9 signaling pathway

Cellular Component

GO:0016324  apical plasma membrane
GO:0016323  basolateral plasma membrane
GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0032009  early phagosome
GO:0005783  endoplasmic reticulum
GO:0005768  endosome
GO:0016021  integral to membrane
GO:0005764  lysosome
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005149  interleukin-1 receptor binding
GO:0005515  protein binding
GO:0035197  siRNA binding
GO:0004888  transmembrane receptor activity