insulin-like growth factor 1

詳細情報を見る

同義遺伝子名

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発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

EST 大脳:12 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:177.70 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:441.60 骨:78.10 皮膚:235.40
GeneChip 大脳:8.39 小脳:8.13 脳幹:8.31 脳梁:- 松果体:- 末梢神経:8.23 脊柱:- 網膜:- 目:8.81 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:8.62 胸腺:7.99 骨髄:8.94 脂肪:- 骨:- 皮膚:-
CAGE nodata
RNA-seq nodata
EST 子宮:- 胎盤:- 前立腺:- 卵巣:228.20 精巣:- 心臓:116.30 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:465.40        肺:50.70    膀胱:- 腎臓:- 下垂体:118.40 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:8.11 骨格筋:8.28 食道:- 胃:- 腸:7.74 結腸:7.98 肝臓:- 肺:- 膀胱:- 腎臓:8.19 下垂体:8.39 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
CAGE nodata
RNA-seq nodata

IDs

Refseq ID NM_001082477
Gene ID 24482
Unigene ID Rn.6282
Probe set ID M15481_at  [RG_U34A]
Ensembl ID ENSRNOG00000004517

オーソログ対応遺伝子

ヒト[14]  NM_000618, NM_001111283, NM_001111284, NM_001111285
マウス[13]  NM_001111274, NM_001111275, NM_001111276, NM_010512, NM_184052

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed  (Pubmed ID)

1368571
1605853
2538424
2772560
3034909
3453891
3595538
3619921
3652906
3658684
7608381
8493451
8528247
8674839
8857020
8889548
9135074
9347796
9716657
9857239
10727985
10827403
10973501
11181517
11474477
11572795
11672597
11675876
11701291
11796174
11834488
11849991
11914039
11934830
11964096
11999215
12002507
12006713
12021178
12057928
12115579
12130673
12135130
12139923
12223347
12239091
12352620
12388149
12395318
12415260
12477932
12485837
12586785
12588046
12593720
12612011
12624094
12624434
12626499
12637793
12682066
12692175
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12764579
12773315
12800242
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12837295
12876289
12902319
12957504
12960075
13129855
14506616
14512843
14532269
14592960
14624474
14711902
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14997011
15042585
15050532
15060019
15070850
15272025
15284206
15356074
15476580
15489316
15521962
15530650
15544842
15567334
15609625
15611844
15625284
15632127
15653207
15668985
15701575
15790724
15793718
15800930
15831712
15833775
15845077
15862547
15917159
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15996002
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16999977
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17023532
17033095
17038487
17103039
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17194636
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17299765
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19375852
19382144
19382214
19397962
19406747
19437499
19438508
19453943
19509289
19587145
19720043
19726620
19726638
19766709
19816949
19850049
19899713
19911128
19916171
19920079
19926099
20013160
20039316
20042609
20085549
20097715
20098680
20160126
20200966
20207740
20213470
20214047
20235220
20347065
20350589
20378540
20435602
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20713758
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20942583
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21054577
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23584855
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23681983
23709620
23721666
23745035
23774069
23843538
23865718
24029240
24049436
24188094
24423253
24440782
24499417
24530896
24617524

遺伝子オントロジー  (GO ID)

Biological Process

GO:0001974  blood vessel remodeling
GO:0048754  branching morphogenesis of a tube
GO:0048468  cell development
GO:0050650  chondroitin sulfate proteoglycan biosynthetic process
GO:0031017  exocrine pancreas development
GO:0007565  female pregnancy
GO:0010001  glial cell differentiation
GO:0048839  inner ear development
GO:0048009  insulin-like growth factor receptor signaling pathway
GO:0048286  lung alveolus development
GO:0030324  lung development
GO:0060463  lung lobe morphogenesis
GO:0060426  lung vasculature development
GO:0030879  mammary gland development
GO:0007613  memory
GO:0035264  multicellular organism growth
GO:0014896  muscle hypertrophy
GO:0045445  myoblast differentiation
GO:0051450  myoblast proliferation
GO:0014904  myotube cell development
GO:0060766  negative regulation of androgen receptor signaling pathway
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0008285  negative regulation of cell proliferation
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0090201  negative regulation of release of cytochrome c from mitochondria
GO:0034392  negative regulation of smooth muscle cell apoptosis
GO:0007399  nervous system development
GO:0048015  phosphoinositide-mediated signaling
GO:0042104  positive regulation of activated T cell proliferation
GO:0070886  positive regulation of calcineurin-NFAT signaling pathway
GO:0010613  positive regulation of cardiac muscle hypertrophy
GO:0030307  positive regulation of cell growth
GO:0008284  positive regulation of cell proliferation
GO:0043388  positive regulation of DNA binding
GO:0045740  positive regulation of DNA replication
GO:0050679  positive regulation of epithelial cell proliferation
GO:0045600  positive regulation of fat cell differentiation
GO:0048146  positive regulation of fibroblast proliferation
GO:0046326  positive regulation of glucose import
GO:0045725  positive regulation of glycogen biosynthetic process
GO:0045821  positive regulation of glycolysis
GO:0021940  positive regulation of granule cell precursor proliferation
GO:0043568  positive regulation of insulin-like growth factor receptor signaling pathway
GO:0043410  positive regulation of MAPKKK cascade
GO:0045840  positive regulation of mitosis
GO:0045669  positive regulation of osteoblast differentiation
GO:0050731  positive regulation of peptidyl-tyrosine phosphorylation
GO:0014068  positive regulation of phosphoinositide 3-kinase cascade
GO:0033160  positive regulation of protein import into nucleus, translocation
GO:0051897  positive regulation of protein kinase B signaling cascade
GO:0046579  positive regulation of Ras protein signal transduction
GO:0014911  positive regulation of smooth muscle cell migration
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0090031  positive regulation of steroid hormone biosynthetic process
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0042523  positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0060527  prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis
GO:0060740  prostate gland epithelium morphogenesis
GO:0060736  prostate gland growth
GO:0060741  prostate gland stromal morphogenesis
GO:0030166  proteoglycan biosynthetic process
GO:0051924  regulation of calcium ion transport
GO:0042127  regulation of cell proliferation
GO:0032878  regulation of establishment or maintenance of cell polarity
GO:0040014  regulation of multicellular organism growth
GO:0001932  regulation of protein amino acid phosphorylation
GO:0051246  regulation of protein metabolic process
GO:0006417  regulation of translation
GO:0014823  response to activity
GO:0051384  response to glucocorticoid stimulus
GO:0032496  response to lipopolysaccharide
GO:0009612  response to mechanical stimulus
GO:0031667  response to nutrient levels
GO:0014070  response to organic cyclic substance
GO:0010033  response to organic substance
GO:0048545  response to steroid hormone stimulus
GO:0014834  satellite cell maintenance involved in skeletal muscle regeneration
GO:0060509  Type I pneumocyte differentiation
GO:0060510  Type II pneumocyte differentiation
GO:0030104  water homeostasis

Cellular Component

GO:0005615  extracellular space
GO:0005614  interstitial matrix

Molecular Function

GO:0008083  growth factor activity
GO:0005179  hormone activity
GO:0005158  insulin receptor binding
GO:0005159  insulin-like growth factor receptor binding
GO:0005178  integrin binding
GO:0005515  protein binding
GO:0043539  protein serine/threonine kinase activator activity
GO:0005496  steroid binding