Tnf receptor-associated factor 2

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:23.90 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:71.10 動脈:357.10 静脈:- リンパ節:- 末梢血:- 脾臓:234 胸腺:- 骨髄:- 脂肪:- 骨:78.10 皮膚:-
GeneChip 大脳:7.64 小脳:7.54 脳幹:7.24 脳梁:- 松果体:- 末梢神経:8.30 脊柱:- 網膜:- 目:7.65 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:7.46 胸腺:7.65 骨髄:7.46 脂肪:- 骨:- 皮膚:-
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:75.90 卵巣:- 精巣:247 心臓:77.60 骨格筋:- 食道:- 胃:- 腸:- 結腸:-     肝臓:13.30        肺:-    膀胱:- 腎臓:127.60 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
GeneChip 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:7.58 骨格筋:7.50 食道:- 胃:- 腸:7.29 結腸:7.42 肝臓:- 肺:- 膀胱:- 腎臓:7.23 下垂体:8.15 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_001107815
Gene ID 311786
Unigene ID Rn.105232
Probe set ID rc_H32966_at  [RG_U34A]
Ensembl ID ENSRNOG00000006238

オーソログ対応遺伝子

ヒト[1]  NM_021138
マウス[1]  NM_009422

染色体

3p13  [3,693,125  -  3,717,332]

遺伝子ファミリー (Interpro ID)

IPR002083  MATH
IPR012227  TNF receptor-associated factor TRAF
IPR008974  TRAF-like
IPR018957  Zinc finger, C3HC4 RING-type
IPR013083  Zinc finger, RING/FYVE/PHD-type

Link to Pubmed  (Pubmed ID)

9813034
10713108
12050113
12215209
12477932
12655295
12786973
15590916
17626074
19910209
20967881
23085193
24011916

遺伝子オントロジー  (GO ID)

Biological Process

GO:0007250  activation of NF-kappaB-inducing kinase activity
GO:0043623  cellular protein complex assembly
GO:0034351  negative regulation of glial cell apoptosis
GO:0032743  positive regulation of interleukin-2 production
GO:0043507  positive regulation of JUN kinase activity
GO:0051092  positive regulation of NF-kappaB transcription factor activity
GO:0090073  positive regulation of protein homodimerization activity
GO:0002726  positive regulation of T cell cytokine production
GO:0051091  positive regulation of transcription factor activity
GO:0051865  protein autoubiquitination
GO:0030163  protein catabolic process
GO:0006461  protein complex assembly
GO:0051291  protein heterooligomerization
GO:0070207  protein homotrimerization
GO:0070534  protein K63-linked ubiquitination
GO:0042981  regulation of apoptosis
GO:0051023  regulation of immunoglobulin secretion
GO:0046328  regulation of JNK cascade
GO:0007165  signal transduction
GO:0033209  tumor necrosis factor-mediated signaling pathway

Cellular Component

GO:0005938  cell cortex
GO:0005737  cytoplasm
GO:0009898  internal side of plasma membrane
GO:0045121  membrane raft
GO:0043234  protein complex

Molecular Function

GO:0005174  CD40 receptor binding
GO:0019899  enzyme binding
GO:0042802  identical protein binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0005515  protein binding
GO:0032403  protein complex binding
GO:0019903  protein phosphatase binding
GO:0005102  receptor binding
GO:0046625  sphingolipid binding
GO:0031996  thioesterase binding
GO:0005164  tumor necrosis factor receptor binding
GO:0031625  ubiquitin protein ligase binding
GO:0004842  ubiquitin-protein ligase activity
GO:0008270  zinc ion binding