transforming growth factor, beta receptor II

 詳細情報を見る

同義遺伝子名

-

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST nodata
GeneChip 大脳:7.06 小脳:6.88 脳幹:7.36 脳梁:- 松果体:- 末梢神経:7.12 脊柱:- 網膜:- 目:7.32 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:7.10 胸腺:6.91 骨髄:7.27 脂肪:- 骨:- 皮膚:-
CAGE nodata
RNA-seq nodata
殖 筋 消 肝 肺 腎 泌
EST nodata
GeneChip 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:7.29 骨格筋:7.38 食道:- 胃:- 腸:7.02 結腸:6.78 肝臓:- 肺:- 膀胱:- 腎臓:7.14 下垂体:6.77 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-
CAGE nodata
RNA-seq nodata

詳細情報

IDs

Refseq ID NM_031132
Gene ID 81810
Unigene ID -
Probe set ID L09653_s_at  [RG_U34A]
Ensembl ID ENSRNOG00000013265

オーソログ対応遺伝子

ヒト[8]  NM_001024847, NM_003242
マウス[4]  NM_009371, NM_029575

染色体

8q32  [120,593,595  -  120,680,453]

遺伝子ファミリー (Interpro ID)

IPR000333  Activin type II receptor
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR017194  Transforming growth factor-beta receptor, type II
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

7573476
7761852
8106553
8264154
8385453
8759618
8840968
9008650
9010265
9144876
9365135
9507219
9699514
9850059
10198196
10207840
10432381
10547197
10672325
10767079
10789724
11178962
11357481
11381048
11675406
11703592
11866987
11936776
11947899
12051734
12060054
12174910
12183510
12223100
12459253
12545247
12632524
12808151
12815632
12957270
12970754
14585397
14612425
14704634
14718046
14729511
14760070
14988818
15102771
15109563
15235604
15537505
15578192
15613744
15731757
15958511
15961557
16009107
16027248
16360132
16420418
16426643
16611331
16627068
16690877
16733295
16897002
16980036
17077588
17114585
17151307
17392319
17428384
17533113
17613544
17878231
17953362
17972267
18313409
18381416
18662538
18684975
18760335
18772397
19506583
20039857
21146604
21378033
21382347
22425884
22964853
23486519

遺伝子オントロジー  (GO ID)

Biological Process

GO:0032147  activation of protein kinase activity
GO:0007568  aging
GO:0006915  apoptosis
GO:0007420  brain development
GO:0060433  bronchus development
GO:0060434  bronchus morphogenesis
GO:0051216  cartilage development
GO:0007182  common-partner SMAD protein phosphorylation
GO:0007566  embryo implantation
GO:0048701  embryonic cranial skeleton morphogenesis
GO:0009790  embryonic development
GO:0035162  embryonic hemopoiesis
GO:0007369  gastrulation
GO:0048565  gut development
GO:0007507  heart development
GO:0001701  in utero embryonic development
GO:0006917  induction of apoptosis
GO:0002088  lens development in camera-type eye
GO:0030324  lung development
GO:0060463  lung lobe morphogenesis
GO:0060425  lung morphogenesis
GO:0060443  mammary gland morphogenesis
GO:0043011  myeloid dendritic cell differentiation
GO:0060044  negative regulation of cardiac muscle cell proliferation
GO:0008285  negative regulation of cell proliferation
GO:0009887  organ morphogenesis
GO:0031100  organ regeneration
GO:0060021  palate development
GO:0060389  pathway-restricted SMAD protein phosphorylation
GO:0001569  patterning of blood vessels
GO:0018105  peptidyl-serine phosphorylation
GO:0018107  peptidyl-threonine phosphorylation
GO:0002663  positive regulation of B cell tolerance induction
GO:0010634  positive regulation of epithelial cell migration
GO:0002053  positive regulation of mesenchymal cell proliferation
GO:0051138  positive regulation of NK T cell differentiation
GO:0043415  positive regulation of skeletal muscle tissue regeneration
GO:0048661  positive regulation of smooth muscle cell proliferation
GO:0002666  positive regulation of T cell tolerance induction
GO:0002651  positive regulation of tolerance induction to self antigen
GO:0006468  protein amino acid phosphorylation
GO:0006898  receptor-mediated endocytosis
GO:0042127  regulation of cell proliferation
GO:0070723  response to cholesterol
GO:0042493  response to drug
GO:0043627  response to estrogen stimulus
GO:0009749  response to glucose stimulus
GO:0001666  response to hypoxia
GO:0009612  response to mechanical stimulus
GO:0007584  response to nutrient
GO:0014070  response to organic cyclic substance
GO:0010033  response to organic substance
GO:0048545  response to steroid hormone stimulus
GO:0007224  smoothened signaling pathway
GO:0060440  trachea formation
GO:0060439  trachea morphogenesis
GO:0007179  transforming growth factor beta receptor signaling pathway
GO:0001570  vasculogenesis
GO:0042060  wound healing

Cellular Component

GO:0005901  caveola
GO:0009986  cell surface
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0009897  external side of plasma membrane
GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0045121  membrane raft
GO:0043235  receptor complex
GO:0070022  transforming growth factor beta receptor complex

Molecular Function

GO:0005524  ATP binding
GO:0005539  glycosaminoglycan binding
GO:0046872  metal ion binding
GO:0031435  mitogen-activated protein kinase kinase kinase binding
GO:0005515  protein binding
GO:0046982  protein heterodimerization activity
GO:0042803  protein homodimerization activity
GO:0004702  receptor signaling protein serine/threonine kinase activity
GO:0046332  SMAD binding
GO:0050431  transforming growth factor beta binding
GO:0005024  transforming growth factor beta receptor activity
GO:0005026  transforming growth factor beta receptor activity, type II
GO:0004675  transmembrane receptor protein serine/threonine kinase activity
GO:0034713  type I transforming growth factor beta receptor binding
GO:0034714  type III transforming growth factor beta receptor binding