bone morphogenic protein receptor, type II (serine/threonine kinase)

同義遺伝子名

2610024H22Rik, AL117858, AW546137, BMPR-II, BMP type II receptor, BMP-2, BB189135, BRK-3, Bone morphogenetic protein receptor type II, Bmpr2

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:60.80

小脳:-

脳幹:31.80

脳梁:-

松果体:-

末梢神経:172

脊柱:236.40

網膜:64.30

目:22.80

動脈:-

静脈:-

リンパ節:10.80

末梢血:-

脾臓:26.30

胸腺:-

骨髄:-

脂肪:-

骨:12.50

皮膚:39.60

GeneChip

大脳:6.05

小脳:5.89

脳幹:-

脳梁:-

松果体:-

末梢神経:7.33

脊柱:5.67

網膜:6.72

目:7.07

動脈:-

静脈:7.14

リンパ節:5.38

末梢血:-

脾臓:5.21

胸腺:-

骨髄:5.13

脂肪:6.16

骨:5.42

皮膚:6.58

CAGE

大脳:1.87

小脳:-

脳幹:1.58

脳梁:-

松果体:-

末梢神経:-

脊柱:1.99

網膜:-

目:-

動脈:2.21

静脈:-

リンパ節:1.28

末梢血:-

脾臓:0.29

胸腺:0.49

骨髄:-

脂肪:-

骨:0

皮膚:1.86

RNA-seq

大脳:1.97

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:151.90

前立腺:30.90

卵巣:68.90

精巣:14.80

心臓:-

骨格筋:71

食道:-

胃:-

腸:-

結腸:35.20

肝臓:18.10

肺:40.20

膀胱:66.20

腎臓:8.10

下垂体:-

甲状腺:-

副腎:424.40

膵臓:9.40

乳腺:71.80

唾液腺:-

GeneChip

子宮:5.43

胎盤:8.26

前立腺:5.82

卵巣:6.89

精巣:5.03

心臓:6.65

骨格筋:6.81

食道:-

胃:5.61

腸:5.66

結腸:-

肝臓:5.97

肺:8.17

膀胱:6.64

腎臓:5.77

下垂体:5.55

甲状腺:-

副腎:6.07

膵臓:6.18

乳腺:5.84

唾液腺:5.85

CAGE

子宮:1.46

胎盤:1.79

前立腺:0.63

卵巣:2.68

精巣:0.45

心臓:-

骨格筋:-

食道:-

胃:0

腸:0.84

結腸:1.03

肝臓:1.64

肺:3.25

膀胱:1.66

腎臓:-

下垂体:1.48

甲状腺:-

副腎:2.26

膵臓:1.84

乳腺:0.69

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:2.18

食道:-

胃:-

腸:-

結腸:-

肝臓:2.87

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_007561
Gene ID	12168
Unigene ID	Mm.391654
Probe set ID	1419616_at [Mouse430_2]
Ensembl ID	ENSMUSG00000067336

オーソログ対応遺伝子

ヒト[2]	NM_001204
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

遺伝子オントロジー (GO ID)

Biological Process

GO:0009952	anterior/posterior pattern formation
GO:0060840	artery development
GO:0001974	blood vessel remodeling
GO:0030509	BMP signaling pathway
GO:0048286	lung alveolus development
GO:0001946	lymphangiogenesis
GO:0060836	lymphatic endothelial cell differentiation
GO:0001707	mesoderm formation
GO:0030308	negative regulation of cell growth
GO:0003085	negative regulation of systemic arterial blood pressure
GO:0045906	negative regulation of vasoconstriction
GO:0016310	phosphorylation
GO:0030513	positive regulation of BMP signaling pathway
GO:0030501	positive regulation of bone mineralization
GO:0010595	positive regulation of endothelial cell migration
GO:0001938	positive regulation of endothelial cell proliferation
GO:0010634	positive regulation of epithelial cell migration
GO:0045669	positive regulation of osteoblast differentiation
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0001934	positive regulation of protein amino acid phosphorylation
GO:0006468	protein amino acid phosphorylation
GO:0042127	regulation of cell proliferation
GO:0014916	regulation of lung blood pressure
GO:0006366	transcription from RNA polymerase II promoter
GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0048010	vascular endothelial growth factor receptor signaling pathway
GO:0060841	venous blood vessel development

Cellular Component

GO:0016324	apical plasma membrane
GO:0009925	basal plasma membrane
GO:0005901	caveola
GO:0043025	cell soma
GO:0009986	cell surface
GO:0005737	cytoplasm
GO:0030425	dendrite
GO:0016021	integral to membrane
GO:0005887	integral to plasma membrane
GO:0016020	membrane
GO:0005886	plasma membrane

Molecular Function

GO:0005524	ATP binding
GO:0019838	growth factor binding
GO:0016301	kinase activity
GO:0046872	metal ion binding
GO:0000166	nucleotide binding
GO:0004672	protein kinase activity
GO:0004674	protein serine/threonine kinase activity
GO:0016740	transferase activity
GO:0016772	transferase activity, transferring phosphorus-containing groups
GO:0005024	transforming growth factor beta receptor activity
GO:0004675	transmembrane receptor protein serine/threonine kinase activity

bone morphogenic protein receptor, type II (serine/threonine kinase)

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function