breast cancer 1

詳細情報を見る

同義遺伝子名

Brca1, breast cancer 1

正常組織・臓器 40分類
正常組織 (発生期含む)・初代培養細胞（FANTOM5 CAGE）

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類の発現パターンを使用しています。

組織40分類別データ

脳

血

結

EST

大脳:72.90

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:32.10

目:60.80

動脈:-

静脈:-

リンパ節:32.40

末梢血:-

脾臓:52.70

胸腺:59.30

骨髄:-

脂肪:-

骨:25

皮膚:39.60

GeneChip

大脳:4.20

小脳:4

脳幹:-

脳梁:-

松果体:-

末梢神経:4.13

脊柱:4.36

網膜:3.79

目:3.94

動脈:-

静脈:4.21

リンパ節:4.75

末梢血:-

脾臓:4.83

胸腺:-

骨髄:7.48

脂肪:3.95

骨:6.57

皮膚:4.07

CAGE

大脳:0.10

小脳:-

脳幹:0.25

脳梁:-

松果体:-

末梢神経:-

脊柱:0.44

網膜:-

目:-

動脈:0.62

静脈:-

リンパ節:2.31

末梢血:-

脾臓:3.70

胸腺:2.99

骨髄:-

脂肪:-

骨:3.41

皮膚:1.81

RNA-seq

大脳:0.59

小脳:-

脳幹:-

脳梁:-

松果体:-

末梢神経:-

脊柱:-

網膜:-

目:-

動脈:-

静脈:-

リンパ節:-

末梢血:-

脾臓:-

胸腺:-

骨髄:-

脂肪:-

骨:-

皮膚:-

殖

筋

消

肝

肺

腎

泌

EST

子宮:-

胎盤:-

前立腺:61.80

卵巣:172.40

精巣:36.90

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:-

肺:30.10

膀胱:-

腎臓:24.20

下垂体:-

甲状腺:-

副腎:-

膵臓:93.80

乳腺:26.10

唾液腺:-

GeneChip

子宮:4.59

胎盤:4.38

前立腺:4.11

卵巣:4.47

精巣:5.67

心臓:4.12

骨格筋:4.05

食道:-

胃:4.32

腸:4.84

結腸:-

肝臓:4.31

肺:3.94

膀胱:3.96

腎臓:3.82

下垂体:4.20

甲状腺:-

副腎:3.81

膵臓:4.26

乳腺:4.06

唾液腺:3.98

CAGE

子宮:1.84

胎盤:1.73

前立腺:0.37

卵巣:1.94

精巣:2.51

心臓:-

骨格筋:-

食道:-

胃:1.07

腸:2.06

結腸:2.00

肝臓:0.64

肺:0.44

膀胱:0.68

腎臓:-

下垂体:0.86

甲状腺:-

副腎:0.47

膵臓:0

乳腺:1.99

唾液腺:-

RNA-seq

子宮:-

胎盤:-

前立腺:-

卵巣:-

精巣:-

心臓:-

骨格筋:-

食道:-

胃:-

腸:-

結腸:-

肝臓:1.68

肺:-

膀胱:-

腎臓:-

下垂体:-

甲状腺:-

副腎:-

膵臓:-

乳腺:-

唾液腺:-

IDs

Refseq ID	NM_009764
Gene ID	12189
Unigene ID	Mm.244975
Probe set ID	1424630_a_at [Mouse430_2]
Ensembl ID	ENSMUSG00000017146

オーソログ対応遺伝子

ヒト[9]	NM_007294, NM_007297, NM_007298, NM_007299, NM_007300
ラット [0]

染色体

遺伝子ファミリー (Interpro ID)

IPR011364	BRCA1
IPR002378	Breast cancer type I susceptibility protein

遺伝子オントロジー (GO ID)

Biological Process

GO:0007049	cell cycle
GO:0007098	centrosome cycle
GO:0051298	centrosome duplication
GO:0043009	chordate embryonic development
GO:0007059	chromosome segregation
GO:0008630	DNA damage response, signal transduction resulting in induction of apoptosis
GO:0006310	DNA recombination
GO:0006281	DNA repair
GO:0006260	DNA replication
GO:0009048	dosage compensation, by inactivation of X chromosome
GO:0006302	double-strand break repair
GO:0000724	double-strand break repair via homologous recombination
GO:0006633	fatty acid biosynthetic process
GO:0006631	fatty acid metabolic process
GO:0031572	G2/M transition DNA damage checkpoint
GO:0006349	genetic imprinting
GO:0006629	lipid metabolic process
GO:0045717	negative regulation of fatty acid biosynthetic process
GO:0035067	negative regulation of histone acetylation
GO:0051572	negative regulation of histone H3-K4 methylation
GO:0051573	negative regulation of histone H3-K9 methylation
GO:0045892	negative regulation of transcription, DNA-dependent
GO:0071158	positive regulation of cell cycle arrest
GO:0045739	positive regulation of DNA repair
GO:0035066	positive regulation of histone acetylation
GO:0051571	positive regulation of histone H3-K4 methylation
GO:0051574	positive regulation of histone H3-K9 methylation
GO:0070512	positive regulation of histone H4-K20 methylation
GO:0031398	positive regulation of protein ubiquitination
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0006301	postreplication repair
GO:0051865	protein autoubiquitination
GO:0016567	protein ubiquitination
GO:0044030	regulation of DNA methylation
GO:0006974	response to DNA damage stimulus
GO:0043627	response to estrogen stimulus
GO:0010212	response to ionizing radiation
GO:0034446	substrate adhesion-dependent cell spreading

Cellular Component

GO:0070531	BRCA1-A complex
GO:0031436	BRCA1-BARD1 complex
GO:0005813	centrosome
GO:0005694	chromosome
GO:0000793	condensed chromosome
GO:0000794	condensed nuclear chromosome
GO:0005737	cytoplasm
GO:0031941	filamentous actin
GO:0005925	focal adhesion
GO:0005759	mitochondrial matrix
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0043234	protein complex
GO:0030529	ribonucleoprotein complex
GO:0001726	ruffle

Molecular Function

GO:0003684	damaged DNA binding
GO:0003677	DNA binding
GO:0044212	DNA regulatory region binding
GO:0019899	enzyme binding
GO:0016874	ligase activity
GO:0046872	metal ion binding
GO:0003723	RNA binding
GO:0031625	ubiquitin protein ligase binding
GO:0004842	ubiquitin-protein ligase activity
GO:0008270	zinc ion binding

breast cancer 1

同義遺伝子名

発現データ

発現マップ on BodyParts3D

組織40分類別データ

詳細情報

IDs

オーソログ対応遺伝子

染色体

遺伝子ファミリー (Interpro ID)

Link to Pubmed (Pubmed ID)

遺伝子オントロジー (GO ID)

Biological Process

Cellular Component

Molecular Function