Eph receptor A1

 詳細情報を見る

同義遺伝子名

5730453L17Rik, AL033318, Eph receptor A1, Ephrin type-A receptor 1 precursor, Esk, Epha1, Tyrosine-protein kinase receptor ESK, Eph

発現データ

発現マップ on BodyParts3D

相対発現量を、人体 3D 画像にマップしたものです。Genechip 組織40分類 の発現パターンを使用しています。

組織40分類別データ

脳 血 結
EST 大脳:8.70 小脳:- 脳幹:63.60 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:7.60 動脈:- 静脈:- リンパ節:- 末梢血:43.10 脾臓:- 胸腺:98.80 骨髄:- 脂肪:- 骨:25 皮膚:79.20
GeneChip 大脳:4.53 小脳:4.55 脳幹:- 脳梁:- 松果体:- 末梢神経:4.59 脊柱:4.67 網膜:4.76 目:5.65 動脈:- 静脈:6.29 リンパ節:4.95 末梢血:- 脾臓:4.91 胸腺:- 骨髄:4.83 脂肪:5.37 骨:4.58 皮膚:8.20
CAGE 大脳:0.45 小脳:- 脳幹:0.44 脳梁:- 松果体:- 末梢神経:- 脊柱:0.44 網膜:- 目:- 動脈:1.01 静脈:- リンパ節:0 末梢血:- 脾臓:0 胸腺:1.06 骨髄:- 脂肪:- 骨:0 皮膚:3.84
RNA-seq 大脳:10.95 小脳:- 脳幹:- 脳梁:- 松果体:- 末梢神経:- 脊柱:- 網膜:- 目:- 動脈:- 静脈:- リンパ節:- 末梢血:- 脾臓:- 胸腺:- 骨髄:- 脂肪:- 骨:- 皮膚:-
殖 筋 消 肝 肺 腎 泌
EST 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:71 食道:- 胃:- 腸:37 結腸:70.50     肝臓:36.20        肺:40.20    膀胱:66.20 腎臓:32.20 下垂体:51.70 甲状腺:- 副腎:- 膵臓:37.50 乳腺:22.90 唾液腺:-
GeneChip 子宮:6.96 胎盤:6.27 前立腺:6.75 卵巣:5.35 精巣:4.69 心臓:4.99 骨格筋:4.93 食道:- 胃:7.04 腸:7.76 結腸:- 肝臓:7.59 肺:6.20 膀胱:6.73 腎臓:6.28 下垂体:5.57 甲状腺:- 副腎:4.77 膵臓:6.23 乳腺:5.39 唾液腺:5.93
CAGE 子宮:2.32 胎盤:1.94 前立腺:1.97 卵巣:1.09 精巣:0 心臓:- 骨格筋:- 食道:- 胃:2.52 腸:4.08 結腸:3.76     肝臓:3.33    肺:2.48 膀胱:3.06 腎臓:- 下垂体:1.63 甲状腺:- 副腎:0.14 膵臓:1.30 乳腺:1.75 唾液腺:-
RNA-seq 子宮:- 胎盤:- 前立腺:- 卵巣:- 精巣:- 心臓:- 骨格筋:1.32 食道:- 胃:- 腸:- 結腸:-     肝臓:3.52        肺:-    膀胱:- 腎臓:- 下垂体:- 甲状腺:- 副腎:- 膵臓:- 乳腺:- 唾液腺:-

詳細情報

IDs

Refseq ID NM_023580
Gene ID 13835
Unigene ID Mm.133330
Probe set ID 1422917_at  [Mouse430_2]
Ensembl ID ENSMUSG00000029859

オーソログ対応遺伝子

ヒト[1]  NM_005232
ラット[1]  NM_001107858

染色体

-

遺伝子ファミリー (Interpro ID)

IPR001090  Ephrin receptor, ligand binding
IPR003961  Fibronectin, type III
IPR008957  Fibronectin, type III-like fold
IPR008979  Galactose-binding domain-like
IPR000719  Protein kinase, catalytic domain
IPR011009  Protein kinase-like domain
IPR002290  Serine/threonine-protein kinase domain
IPR017442  Serine/threonine-protein kinase-like domain
IPR001660  Sterile alpha motif
IPR010993  Sterile alpha motif homology
IPR013761  Sterile alpha motif-type
IPR020685  Tyrosine-protein kinase
IPR001245  Tyrosine-protein kinase, catalytic domain
IPR016257  Tyrosine-protein kinase, ephrin receptor
IPR020933  Tyrosine-protein kinase, fibroblast growth factor receptor, conserved region
IPR020635  Tyrosine-protein kinase, subgroup, catalytic domain

Link to Pubmed  (Pubmed ID)

7671812
8123468
8552593
9267020
9287490
10207129
10349636
10495276
10508149
11042159
11076861
11114734
11217851
11439183
12217323
12466851
12477932
12528186
12775584
14681479
14715945
15254900
15761153
16141072
16141073
16446123
16466970
16547242
16602821
17039519
17145500
18287559
18802966
19247962
19542359
19769959
20112066
21135133
21267068
21677750
21795402
24056079

遺伝子オントロジー  (GO ID)

Biological Process

GO:0032862  activation of Rho GTPase activity
GO:0001525  angiogenesis
GO:0007155  cell adhesion
GO:0007166  cell surface receptor linked signal transduction
GO:0048013  ephrin receptor signaling pathway
GO:0030336  negative regulation of cell migration
GO:0006469  negative regulation of protein kinase activity
GO:0018108  peptidyl-tyrosine phosphorylation
GO:0016310  phosphorylation
GO:0045766  positive regulation of angiogenesis
GO:0030335  positive regulation of cell migration
GO:0008284  positive regulation of cell proliferation
GO:0001954  positive regulation of cell-matrix adhesion
GO:0051496  positive regulation of stress fiber formation
GO:0046777  protein amino acid autophosphorylation
GO:0006468  protein amino acid phosphorylation
GO:0032314  regulation of Rac GTPase activity
GO:0034446  substrate adhesion-dependent cell spreading
GO:0007169  transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0016021  integral to membrane
GO:0005887  integral to plasma membrane
GO:0016020  membrane
GO:0005886  plasma membrane

Molecular Function

GO:0005524  ATP binding
GO:0005003  ephrin receptor activity
GO:0016301  kinase activity
GO:0000166  nucleotide binding
GO:0004672  protein kinase activity
GO:0019901  protein kinase binding
GO:0004713  protein tyrosine kinase activity
GO:0016740  transferase activity
GO:0016772  transferase activity, transferring phosphorus-containing groups
GO:0004714  transmembrane receptor protein tyrosine kinase activity
GO:0005005  transmembrane-ephrin receptor activity