phosphatidylinositol glycan anchor biosynthesis, class K

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Synonym

PIG-K, MGC22559, GPI transamidase, hGPI8, PIGK, GPI-anchor transamidase precursor, GPI8

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:101.90 cerebellum:37.80 brain stem:- corpus callosum/glia:87.50 pineal gland:148.30 peripheral nerve:122.70 spine:- retina:237.30 eye:41.10 artery/aorta:- vein:- lymphnode:30.30 peripheral blood:36.40 spleen:- thymus:64.40 bone marrow:19.70 adipose:40.30 bone:25.60 skin:48
GeneChip cerebrum:5.89 cerebellum:4.95 brain stem:6.20 corpus callosum/glia:6.44 pineal gland:- peripheral nerve:5.83 spine:6.28 retina:- eye:- artery/aorta:6.13 vein:5.55 lymphnode:4.91 peripheral blood:- spleen:5.17 thymus:5.53 bone marrow:5.63 adipose:5.36 bone:- skin:4.95
CAGE cerebrum:3.54 cerebellum:- brain stem:3.89 corpus callosum/glia:3.75 pineal gland:3.85 peripheral nerve:- spine:3.74 retina:- eye:- artery/aorta:3.44 vein:2.75 lymphnode:3.01 peripheral blood:- spleen:3.50 thymus:3.35 bone marrow:- adipose:3.53 bone:- skin:-
RNA-seq cerebrum:3.72 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.50 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.23 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:51 prostate:- ovary:- testis:73.50 heart:- muscle:- esophagus:342.80 stomach:42.50 intestine:64.80 colon:8.50     liver/hepato:42.20        lung:48.90    bladder:125.60 kidney:93.60 pituitary:232 thyroid/parathyroid:- adrenal gland:- pancreas:35.60 breast:37.20 salivary:-
GeneChip uterus:5.59 placenta:4.76 prostate:6.21 ovary:5.37 testis:5.38 heart:5.61 muscle:4.45 esophagus:4.52 stomach:5.41 intestine:5.26 colon:4.80 liver/hepato:5.45 lung:5.12 bladder:- kidney:5.85 pituitary:5.92 thyroid/parathyroid:5.93 adrenal gland:5.42 pancreas:5.35 breast:5.20 salivary:5.77
CAGE uterus:3.29 placenta:3.22 prostate:3.40 ovary:3.41 testis:3.29 heart:3.43 muscle:2.42 esophagus:3.28 stomach:- intestine:3.30 colon:2.98     liver/hepato:3.60    lung:3.34 bladder:3.32 kidney:3.98 pituitary:3.97 thyroid/parathyroid:3.60 adrenal gland:- pancreas:3.34 breast:3.35 salivary:3.22
RNA-seq uterus:- placenta:- prostate:3.35 ovary:3.54 testis:3.38 heart:3.19 muscle:2.44 esophagus:- stomach:- intestine:- colon:3.49     liver/hepato:2.84        lung:3.25    bladder:- kidney:3.93 pituitary:- thyroid/parathyroid:3.54 adrenal gland:3.21 pancreas:- breast:3.66 salivary:-

Gene Information

IDs

Refseq ID NM_005482
Gene ID 10026
Unigene ID Hs.178305
Probe set ID 209707_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000142892
GTEx ID ENSG00000142892

Orthologous Gene

Mouse[4]  NM_025662, NM_178016
Rat[1]  NM_001011953, NM_178016

Chromosomal Region

1p31.1  [77,554,675  -  77,685,115]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1846368
8978684
9356492
10727241
10793132
11278620
11483512
12052837
12477932
12582175
12616539
12802054
14702039
15489334
16196087
16344560
16710414
17207965
18187620
19946888
21139048
21906983
21963094
22268729
22824918
22939629

Gene Ontology  (GO ID)

Biological Process

GO:0016255  attachment of GPI anchor to protein
GO:0006501  C-terminal protein lipidation
GO:0044267  cellular protein metabolic process
GO:0043687  post-translational protein modification
GO:0006457  protein folding
GO:0006508  proteolysis

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0042765  GPI-anchor transamidase complex
GO:0030176  integral to endoplasmic reticulum membrane

Molecular Function

GO:0004197  cysteine-type endopeptidase activity
GO:0034235  GPI anchor binding
GO:0003923  GPI-anchor transamidase activity
GO:0005515  protein binding
GO:0003756  protein disulfide isomerase activity