cyclin-dependent kinase 7

Synonym

p39MO15, CDK7, CDK-activating kinase, MO15, P39 Mo15, 39 kDa protein kinase, CDKN7, Cell division protein kinase 7, CAK1, STK1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:36.70

cerebellum:12.60

brain stem:-

corpus callosum/glia:29.20

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:11.80

artery/aorta:-

vein:133.30

lymphnode:91

peripheral blood:36.40

spleen:-

thymus:-

bone marrow:334.60

adipose:-

bone:-

skin:28.80

GeneChip

cerebrum:5.52

cerebellum:5.45

brain stem:5.59

corpus callosum/glia:5.14

pineal gland:-

peripheral nerve:5.67

spine:5.24

retina:-

eye:-

artery/aorta:5.20

vein:5.33

lymphnode:6.06

peripheral blood:-

spleen:5.58

thymus:6.20

bone marrow:5.43

adipose:5.63

bone:-

skin:6.45

CAGE

cerebrum:2.96

cerebellum:-

brain stem:2.79

corpus callosum/glia:2.46

pineal gland:3.46

peripheral nerve:-

spine:2.91

retina:-

eye:-

artery/aorta:2.74

vein:2.77

lymphnode:2.81

peripheral blood:-

spleen:2.57

thymus:2.89

bone marrow:-

adipose:2.69

bone:-

skin:-

RNA-seq

cerebrum:2.54

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:2.25

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:2.46

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:36.50

placenta:47.40

prostate:45.10

ovary:-

testis:38.90

heart:25.50

muscle:20.10

esophagus:-

stomach:21.20

intestine:32.40

colon:42.40

liver/hepato:31.70

lung:48.90

bladder:-

kidney:10.40

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:130.10

salivary:-

GeneChip

uterus:6.17

placenta:7.08

prostate:6.54

ovary:6.67

testis:7.52

heart:5.33

muscle:6.27

esophagus:7.34

stomach:5.56

intestine:5.69

colon:5.28

liver/hepato:5.03

lung:5.73

bladder:-

kidney:5.75

pituitary:5.92

thyroid/parathyroid:6.10

adrenal gland:5.81

pancreas:5.57

breast:6.20

salivary:5.56

CAGE

uterus:2.79

placenta:3.56

prostate:2.73

ovary:2.48

testis:3.37

heart:2.52

muscle:2.97

esophagus:3.43

stomach:-

intestine:2.84

colon:2.84

liver/hepato:2.79

lung:2.83

bladder:2.96

kidney:3.13

pituitary:3.40

thyroid/parathyroid:2.96

adrenal gland:-

pancreas:2.54

breast:2.27

salivary:3.03

RNA-seq

uterus:-

placenta:-

prostate:2.97

ovary:2.78

testis:4.44

heart:1.78

muscle:2.50

esophagus:-

stomach:-

intestine:-

colon:2.54

liver/hepato:1.89

lung:2.58

bladder:-

kidney:3.22

pituitary:-

thyroid/parathyroid:3.69

adrenal gland:2.96

pancreas:-

breast:3.03

salivary:-

IDs

Refseq ID	NM_001799
Gene ID	1022
Unigene ID	Hs.184298
Probe set ID	211297_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000134058
GTEx ID	ENSG00000134058

Orthologous Gene

Mouse[2]	NM_009874
Rat[2]	NM_009874

Chromosomal Region

5q13.2 [68,530,668 - 68,573,250]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR000719	Protein kinase, catalytic domain
IPR011009	Protein kinase-like domain
IPR002290	Serine/threonine-protein kinase domain
IPR017442	Serine/threonine-protein kinase-like domain
IPR001245	Tyrosine-protein kinase, catalytic domain
IPR020635	Tyrosine-protein kinase, subgroup, catalytic domain

Gene Ontology (GO ID)

Biological Process

GO:0030521	androgen receptor signaling pathway
GO:0007050	cell cycle arrest
GO:0051301	cell division
GO:0008283	cell proliferation
GO:0006281	DNA repair
GO:0000082	G1/S transition of mitotic cell cycle
GO:0000086	G2/M transition of mitotic cell cycle
GO:0010467	gene expression
GO:0000278	mitotic cell cycle
GO:0006370	mRNA capping
GO:0006289	nucleotide-excision repair
GO:0000718	nucleotide-excision repair, DNA damage removal
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0045893	positive regulation of transcription, DNA-dependent
GO:0050434	positive regulation of viral transcription
GO:0000079	regulation of cyclin-dependent protein kinase activity
GO:0006362	RNA elongation from RNA polymerase I promoter
GO:0006368	RNA elongation from RNA polymerase II promoter
GO:0006363	termination of RNA polymerase I transcription
GO:0006360	transcription from RNA polymerase I promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0006361	transcription initiation from RNA polymerase I promoter
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0006283	transcription-coupled nucleotide-excision repair
GO:0016032	viral reproduction

Cellular Component

GO:0005737	cytoplasm
GO:0005675	holo TFIIH complex
GO:0005739	mitochondrion
GO:0005654	nucleoplasm
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm

Molecular Function

GO:0050681	androgen receptor binding
GO:0005524	ATP binding
GO:0004693	cyclin-dependent protein kinase activity
GO:0008094	DNA-dependent ATPase activity
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0004672	protein kinase activity
GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity
GO:0003713	transcription coactivator activity

cyclin-dependent kinase 7

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function