cyclin O

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Synonym

FLJ22422, UDG 2, UDG2, uracil-DNA glycosylase 2, Uracil-DNA glycosylase 2, UNG2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:131.60 cerebellum:352.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:122.70 spine:673.80 retina:237.30 eye:182.20 artery/aorta:119.90 vein:599.80 lymphnode:70.80 peripheral blood:18.20 spleen:18.90 thymus:- bone marrow:- adipose:242 bone:51.20 skin:168
GeneChip cerebrum:4.72 cerebellum:4.53 brain stem:4.49 corpus callosum/glia:4.43 pineal gland:- peripheral nerve:4.33 spine:4.49 retina:- eye:- artery/aorta:4.59 vein:4.35 lymphnode:4.31 peripheral blood:- spleen:4.08 thymus:3.94 bone marrow:4.43 adipose:4.42 bone:- skin:4.71
CAGE cerebrum:1.82 cerebellum:- brain stem:0.16 corpus callosum/glia:1.19 pineal gland:1.14 peripheral nerve:- spine:0.36 retina:- eye:- artery/aorta:1.61 vein:0 lymphnode:0.61 peripheral blood:- spleen:0.17 thymus:0.23 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:1.36 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.09 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.20 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:537.70 placenta:225.90 prostate:236.60 ovary:149.10 testis:95.20 heart:344.80 muscle:- esophagus:2742.50 stomach:276.10 intestine:648 colon:203.50     liver/hepato:73.90        lung:141.70    bladder:125.60 kidney:135.20 pituitary:- thyroid/parathyroid:- adrenal gland:304.70 pancreas:133.40 breast:223 salivary:656.80
GeneChip uterus:4.37 placenta:4.14 prostate:4.73 ovary:4.42 testis:6.28 heart:4.27 muscle:4.32 esophagus:4.43 stomach:4.99 intestine:4.82 colon:4.38 liver/hepato:4.33 lung:4.17 bladder:- kidney:4.51 pituitary:5.30 thyroid/parathyroid:5.48 adrenal gland:4.29 pancreas:5.12 breast:4.62 salivary:4.94
CAGE uterus:0.56 placenta:0.08 prostate:1.34 ovary:0.76 testis:2.89 heart:0.17 muscle:0 esophagus:0.73 stomach:- intestine:0.61 colon:0.21     liver/hepato:0.26    lung:1.40 bladder:1.18 kidney:1.55 pituitary:2.12 thyroid/parathyroid:2.49 adrenal gland:- pancreas:2.66 breast:1.16 salivary:1.82
RNA-seq uterus:- placenta:- prostate:0.99 ovary:0.74 testis:2.81 heart:0.04 muscle:0 esophagus:- stomach:- intestine:- colon:0.34     liver/hepato:0.13        lung:0.88    bladder:- kidney:1.04 pituitary:- thyroid/parathyroid:1.64 adrenal gland:0.12 pancreas:- breast:0.29 salivary:-

Gene Information

IDs

Refseq ID NM_021147
Gene ID 10309
Unigene ID Hs.304192
Probe set ID 210021_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000152669
GTEx ID ENSG00000152669

Orthologous Gene

Mouse[1]  NM_001081062
Rat [0]  

Chromosomal Region

5q11.2  [54,526,980  -  54,529,508]

Gene Family (Interpro ID)

IPR014400  Cyclin, A/B/D/E
IPR011028  Cyclin-like
IPR013763  Cyclin-related

Link to Pubmed  (Pubmed ID)

2001396
8419333
10393198
11081631
12161446
12171929
12477932
14702039
15372022
15489334
18654987
20360068
21226479
22292079
23849790
24747639
24824133

Gene Ontology  (GO ID)

Biological Process

GO:0006284  base-excision repair
GO:0006285  base-excision repair, AP site formation
GO:0007049  cell cycle
GO:0051301  cell division
GO:0045008  depyrimidination
GO:0006281  DNA repair
GO:0000079  regulation of cyclin-dependent protein kinase activity

Cellular Component

GO:0005654  nucleoplasm

Molecular Function

GO:0019901  protein kinase binding
GO:0004844  uracil DNA N-glycosylase activity