proteoglycan 3

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Synonym

proteoglycan 3, UNQ486/PRO1002, MBPH, PRG3, Prepro-MBPH, Proteoglycan 3 precursor, MGC141971, MGC126662, Eosinophil major basic protein homolog, Prepro-major basic protein homolog

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:19.70 adipose:- bone:- skin:-
GeneChip cerebrum:4.11 cerebellum:4.10 brain stem:4.16 corpus callosum/glia:4.08 pineal gland:- peripheral nerve:4.10 spine:4.14 retina:- eye:- artery/aorta:4.23 vein:4.24 lymphnode:4.19 peripheral blood:- spleen:4.09 thymus:4.39 bone marrow:9.03 adipose:4.23 bone:- skin:4.52
CAGE cerebrum:0.01 cerebellum:- brain stem:0 corpus callosum/glia:0.13 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0.39 thymus:0.88 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.06 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:3.98 placenta:4.36 prostate:3.89 ovary:3.94 testis:4.07 heart:4.08 muscle:4.09 esophagus:4.13 stomach:4.04 intestine:4.02 colon:4.65 liver/hepato:4.15 lung:3.89 bladder:- kidney:4.19 pituitary:4.36 thyroid/parathyroid:4.11 adrenal gland:4.16 pancreas:4.70 breast:4.13 salivary:4.14
CAGE uterus:0 placenta:0.08 prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0.21 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:1.12    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_006093
Gene ID 10394
Unigene ID Hs.251386
Probe set ID 220811_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000156575
GTEx ID ENSG00000156575

Orthologous Gene

Mouse[1]  NM_016914
Rat [0]  

Chromosomal Region

11q12.1  [57,144,242  -  57,148,623]

Gene Family (Interpro ID)

IPR001304  C-type lectin
IPR016187  C-type lectin fold
IPR016186  C-type lectin-like

Link to Pubmed  (Pubmed ID)

10318872
11170744
12477932
12975309
15489334
17136616
17308074
20379614
21048031
22412388

Gene Ontology  (GO ID)

Biological Process

GO:0045575  basophil activation
GO:0001694  histamine biosynthetic process
GO:0006955  immune response
GO:0019370  leukotriene biosynthetic process
GO:0017148  negative regulation of translation
GO:0042119  neutrophil activation
GO:0045416  positive regulation of interleukin-8 biosynthetic process
GO:0042554  superoxide anion generation

Molecular Function

GO:0030246  carbohydrate binding