polymerase (RNA) III (DNA directed) polypeptide C (62kD)

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Synonym

RNA polymerase C subunit 3, RPC62, RNA polymerase III C62 subunit, RPC3, DNA-directed RNA polymerase III 62 kDa polypeptide, POLR3C

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:20.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:148.30 peripheral nerve:- spine:112.30 retina:- eye:11.80 artery/aorta:60 vein:- lymphnode:101.10 peripheral blood:91.10 spleen:- thymus:12.90 bone marrow:137.80 adipose:- bone:38.40 skin:28.80
GeneChip cerebrum:5.34 cerebellum:5.47 brain stem:5.37 corpus callosum/glia:5.17 pineal gland:- peripheral nerve:5.42 spine:5.38 retina:- eye:- artery/aorta:5.40 vein:5.30 lymphnode:5.30 peripheral blood:- spleen:5.27 thymus:5.80 bone marrow:5.73 adipose:5.59 bone:- skin:5.54
CAGE cerebrum:2.86 cerebellum:- brain stem:2.85 corpus callosum/glia:2.75 pineal gland:2.73 peripheral nerve:- spine:2.70 retina:- eye:- artery/aorta:2.88 vein:3.31 lymphnode:3.25 peripheral blood:- spleen:3.19 thymus:3.28 bone marrow:- adipose:3.17 bone:- skin:-
RNA-seq cerebrum:3.05 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.92 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.59 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:36.40 prostate:22.50 ovary:37.30 testis:30.30 heart:12.80 muscle:40.20 esophagus:- stomach:169.90 intestine:- colon:42.40     liver/hepato:-        lung:24.40    bladder:- kidney:83.20 pituitary:- thyroid/parathyroid:163.70 adrenal gland:- pancreas:- breast:148.70 salivary:-
GeneChip uterus:5.52 placenta:5.83 prostate:5.44 ovary:5.65 testis:6.67 heart:5.49 muscle:5.49 esophagus:5.52 stomach:5.25 intestine:5.43 colon:5.54 liver/hepato:5.03 lung:4.87 bladder:- kidney:5.36 pituitary:5.45 thyroid/parathyroid:5.15 adrenal gland:5.47 pancreas:5.91 breast:5.61 salivary:5.84
CAGE uterus:3.06 placenta:2.60 prostate:3.01 ovary:3.11 testis:3.54 heart:2.78 muscle:2.72 esophagus:2.67 stomach:- intestine:2.69 colon:2.77     liver/hepato:2.62    lung:2.85 bladder:2.93 kidney:2.90 pituitary:2.65 thyroid/parathyroid:2.89 adrenal gland:- pancreas:3.20 breast:3.06 salivary:2.72
RNA-seq uterus:- placenta:- prostate:3.75 ovary:3.88 testis:4.76 heart:2.61 muscle:3.01 esophagus:- stomach:- intestine:- colon:2.78     liver/hepato:2.14        lung:2.24    bladder:- kidney:3.12 pituitary:- thyroid/parathyroid:3.85 adrenal gland:4.05 pancreas:- breast:3.41 salivary:-

Gene Information

IDs

Refseq ID NM_006468
Gene ID 10623
Unigene ID Hs.591457
Probe set ID 210573_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000186141
GTEx ID ENSG00000186141

Orthologous Gene

Mouse[2]  NM_028925
Rat[1]  NM_001012081

Chromosomal Region

1q21.1  [145,592,605  -  145,611,025]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1403646
8125298
9171375
10373544
10523658
12384934
12391170
12477932
15489334
17643375
18029348
19609254
20970119
21139048
21358628
21832049
21890473
21906983
22939629
23000965
23383273
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0051607  defense response to virus
GO:0010467  gene expression
GO:0045087  innate immune response
GO:0045089  positive regulation of innate immune response
GO:0032728  positive regulation of interferon-beta production
GO:0032481  positive regulation of type I interferon production
GO:0006359  regulation of transcription from RNA polymerase III promoter
GO:0006385  RNA elongation from RNA polymerase III promoter
GO:0006386  termination of RNA polymerase III transcription
GO:0006383  transcription from RNA polymerase III promoter

Cellular Component

GO:0005829  cytosol
GO:0005666  DNA-directed RNA polymerase III complex
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0003899  DNA-directed RNA polymerase activity