regulator of G-protein signaling 14

 jump to detail

Synonym

RGS14, regulator of G-protein signalling 14, Regulator of G-protein signaling 14

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:28.40 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:29.40 artery/aorta:- vein:- lymphnode:70.80 peripheral blood:36.40 spleen:37.80 thymus:12.90 bone marrow:39.40 adipose:- bone:- skin:-
GeneChip cerebrum:5.85 cerebellum:5.10 brain stem:5.39 corpus callosum/glia:5.13 pineal gland:- peripheral nerve:5.04 spine:4.80 retina:- eye:- artery/aorta:5.36 vein:5.40 lymphnode:5.95 peripheral blood:- spleen:6.20 thymus:6.13 bone marrow:6.14 adipose:5.61 bone:- skin:5.74
CAGE cerebrum:2.38 cerebellum:- brain stem:1.07 corpus callosum/glia:1.70 pineal gland:0.14 peripheral nerve:- spine:0.85 retina:- eye:- artery/aorta:1.48 vein:3.41 lymphnode:3.55 peripheral blood:- spleen:3.42 thymus:3.82 bone marrow:- adipose:1.37 bone:- skin:-
RNA-seq cerebrum:2.24 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.94 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.82 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:78.90 ovary:37.30 testis:8.70 heart:12.80 muscle:20.10 esophagus:- stomach:- intestine:- colon:17     liver/hepato:-        lung:4.90    bladder:251.20 kidney:166.40 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:44.50 breast:- salivary:-
GeneChip uterus:5.19 placenta:4.63 prostate:5.11 ovary:5.25 testis:5.28 heart:5.31 muscle:5.62 esophagus:6.14 stomach:5.27 intestine:5.72 colon:5.60 liver/hepato:5.91 lung:5.32 bladder:- kidney:5.60 pituitary:5.26 thyroid/parathyroid:5.32 adrenal gland:5.21 pancreas:5.72 breast:5.21 salivary:5.69
CAGE uterus:1.60 placenta:1.14 prostate:1.83 ovary:1.11 testis:1.10 heart:0.95 muscle:1.04 esophagus:3.26 stomach:- intestine:2.00 colon:2.31     liver/hepato:2.83    lung:2.41 bladder:1.18 kidney:2.67 pituitary:0.83 thyroid/parathyroid:0.98 adrenal gland:- pancreas:0.58 breast:1.36 salivary:2.22
RNA-seq uterus:- placenta:- prostate:1.56 ovary:1.62 testis:1.53 heart:0.49 muscle:0.22 esophagus:- stomach:- intestine:- colon:0.89     liver/hepato:2.68        lung:2.00    bladder:- kidney:2.67 pituitary:- thyroid/parathyroid:1.24 adrenal gland:2.87 pancreas:- breast:1.05 salivary:-

Gene Information

IDs

Refseq ID NM_006480
Gene ID 10636
Unigene ID Hs.9347
Probe set ID 204280_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000169220
GTEx ID ENSG00000169220

Orthologous Gene

Mouse[1]  NM_016758
Rat [0]  

Chromosomal Region

5q35.3  [176,784,838  -  176,799,602]

Gene Family (Interpro ID)

IPR000342  Regulator of G protein signalling
IPR016137  Regulator of G protein signalling superfamily

Link to Pubmed  (Pubmed ID)

9168931
10926822
10953050
11387333
11829488
11976690
12477932
12534294
14702039
15489334
15525537
15917656
16189514
17603074
17635935
18029348
19636837
19878719
19899154
20383146
20627871
20842066
21044950
21832049
21833088
21880739
21988832
22379092
22396660
22703881
22797727
22807448
23128233
24068962

Gene Ontology  (GO ID)

Biological Process

GO:0051301  cell division
GO:0007059  chromosome segregation
GO:0007612  learning
GO:0007616  long-term memory
GO:0060291  long-term synaptic potentiation
GO:0007067  mitosis
GO:0070373  negative regulation of ERK1 and ERK2 cascade
GO:0043407  negative regulation of MAP kinase activity
GO:0031914  negative regulation of synaptic plasticity
GO:0006913  nucleocytoplasmic transport
GO:0048008  platelet-derived growth factor receptor signaling pathway
GO:0043547  positive regulation of GTPase activity
GO:0050769  positive regulation of neurogenesis
GO:0008277  regulation of G-protein coupled receptor protein signaling pathway
GO:0043620  regulation of transcription in response to stress
GO:0006979  response to oxidative stress
GO:0007051  spindle organization
GO:0008542  visual learning
GO:0010070  zygote asymmetric cell division

Cellular Component

GO:0030054  cell junction
GO:0005813  centrosome
GO:0005737  cytoplasm
GO:0030425  dendrite
GO:0043197  dendritic spine
GO:0045111  intermediate filament cytoskeleton
GO:0005874  microtubule
GO:0016604  nuclear body
GO:0005730  nucleolus
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0016605  PML body
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane
GO:0005819  spindle
GO:0000922  spindle pole

Molecular Function

GO:0005092  GDP-dissociation inhibitor activity
GO:0032794  GTPase activating protein binding
GO:0005096  GTPase activator activity
GO:0008017  microtubule binding
GO:0019901  protein kinase binding
GO:0030159  receptor signaling complex scaffold activity
GO:0005057  receptor signaling protein activity