euchromatic histone-lysine N-methyltransferase 2

Synonym

HLA-B-associated transcript 8, NG36/G9a, HLA-B associated transcript 8, G9A, Em:AF134726.3, C6orf30, BAT8, Protein G9a, Euchromatic histone-lysine N-methyltransferase 2, euchromatic histone-lysine N-methyltransferase 2, H3-K9-HMTase 3, chromosome 6 open reading frame 30, NG36, EHMT2, Histone H3-K9 methyltransferase 3

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

nodata

GeneChip

cerebrum:6.78

cerebellum:6.82

brain stem:6.88

corpus callosum/glia:6.81

pineal gland:-

peripheral nerve:6.30

spine:6.53

retina:-

eye:-

artery/aorta:6.46

vein:6.74

lymphnode:6.62

peripheral blood:-

spleen:6.71

thymus:6.56

bone marrow:6.76

adipose:6.67

bone:-

skin:6.55

CAGE

cerebrum:2.99

cerebellum:-

brain stem:3.18

corpus callosum/glia:3.41

pineal gland:2.87

peripheral nerve:-

spine:2.94

retina:-

eye:-

artery/aorta:3.10

vein:2.99

lymphnode:2.86

peripheral blood:-

spleen:2.79

thymus:3.36

bone marrow:-

adipose:2.63

bone:-

skin:-

RNA-seq

cerebrum:1.97

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:3.25

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:1.40

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

nodata

GeneChip

uterus:6.54

placenta:5.98

prostate:6.40

ovary:6.59

testis:6.96

heart:6.54

muscle:6.78

esophagus:6.56

stomach:6.75

intestine:6.43

colon:6.87

liver/hepato:6.52

lung:6.47

bladder:-

kidney:6.79

pituitary:6.81

thyroid/parathyroid:6.33

adrenal gland:6.58

pancreas:6.44

breast:6.63

salivary:6.73

CAGE

uterus:3.23

placenta:2.67

prostate:3.28

ovary:3.13

testis:3.15

heart:2.46

muscle:2.09

esophagus:2.84

stomach:-

intestine:2.50

colon:2.94

liver/hepato:1.99

lung:2.69

bladder:2.86

kidney:2.31

pituitary:2.47

thyroid/parathyroid:2.96

adrenal gland:-

pancreas:2.26

breast:2.79

salivary:2.80

RNA-seq

uterus:-

placenta:-

prostate:2.70

ovary:2.98

testis:3.07

heart:0.26

muscle:1.61

esophagus:-

stomach:-

intestine:-

colon:1.88

liver/hepato:0.32

lung:1.56

bladder:-

kidney:1.04

pituitary:-

thyroid/parathyroid:1.48

adrenal gland:1.79

pancreas:-

breast:1.53

salivary:-

IDs

Refseq ID	NM_025256
Gene ID	10919
Unigene ID	-
Probe set ID	207484_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000204371 ENSG00000227333 ENSG00000236759
GTEx ID	ENSG00000204371 ENSG00000227333 ENSG00000236759

Orthologous Gene

Mouse[4]	NM_145830, NM_147151
Rat [0]

Chromosomal Region

HSCHR6_MHC_APD [31,858,893 - 31,876,828]

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HSCHR6_MHC_QBL [31,837,931 - 31,855,870]

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HSCHR6_MHC_COX [31,835,086 - 31,853,014]

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HSCHR6_MHC_SSTO [31,839,421 - 31,849,264]

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HSCHR6_MHC_MCF [31,924,012 - 31,941,947]

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6p21.33 [31,847,536 - 31,865,464]

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HSCHR6_MHC_DBB [31,829,721 - 31,847,649]

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Gene Family (Interpro ID)

IPR007728	Pre-SET domain
IPR003606	Pre-SET zinc-binding sub-group

Gene Ontology (GO ID)

Biological Process

GO:0006306	DNA methylation
GO:0010424	DNA methylation on cytosine within a CG sequence
GO:0009566	fertilization
GO:0016571	histone methylation
GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0035265	organ growth
GO:0018027	peptidyl-lysine dimethylation
GO:0006275	regulation of DNA replication
GO:0007286	spermatid development
GO:0007130	synaptonemal complex assembly

Cellular Component

GO:0005694	chromosome
GO:0005634	nucleus

Molecular Function

GO:0046976	histone methyltransferase activity (H3-K27 specific)
GO:0046974	histone methyltransferase activity (H3-K9 specific)
GO:0018024	histone-lysine N-methyltransferase activity
GO:0002039	p53 binding
GO:0005515	protein binding
GO:0016279	protein-lysine N-methyltransferase activity
GO:0008270	zinc ion binding

euchromatic histone-lysine N-methyltransferase 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function