KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

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Synonym

KDELR3, ERD2L3, KDEL receptor 3, ER lumen protein retaining receptor 3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:3.68 cerebellum:3.94 brain stem:3.67 corpus callosum/glia:3.84 pineal gland:- peripheral nerve:3.63 spine:3.67 retina:- eye:- artery/aorta:3.83 vein:3.93 lymphnode:3.79 peripheral blood:- spleen:3.62 thymus:3.79 bone marrow:3.87 adipose:3.79 bone:- skin:3.89
CAGE cerebrum:0.24 cerebellum:- brain stem:0.49 corpus callosum/glia:0.85 pineal gland:0.74 peripheral nerve:- spine:0.79 retina:- eye:- artery/aorta:3.01 vein:1.34 lymphnode:2.45 peripheral blood:- spleen:1.32 thymus:0.42 bone marrow:- adipose:2.55 bone:- skin:-
RNA-seq cerebrum:0.42 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.17 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.08 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:3.86 placenta:3.88 prostate:3.74 ovary:3.86 testis:3.67 heart:3.88 muscle:3.88 esophagus:3.68 stomach:3.79 intestine:4.15 colon:3.86 liver/hepato:3.59 lung:3.81 bladder:- kidney:3.56 pituitary:4.05 thyroid/parathyroid:3.57 adrenal gland:3.65 pancreas:4.08 breast:3.71 salivary:3.90
CAGE uterus:2.30 placenta:2.51 prostate:2.05 ovary:2.14 testis:1.40 heart:2.50 muscle:0.77 esophagus:1.89 stomach:- intestine:2.81 colon:2.25     liver/hepato:3.71    lung:2.04 bladder:2.03 kidney:2.48 pituitary:2.79 thyroid/parathyroid:2.02 adrenal gland:- pancreas:3.89 breast:2.64 salivary:3.84
RNA-seq uterus:- placenta:- prostate:0.06 ovary:0.51 testis:0.44 heart:0.22 muscle:0.20 esophagus:- stomach:- intestine:- colon:0.36     liver/hepato:0        lung:0.53    bladder:- kidney:0.61 pituitary:- thyroid/parathyroid:0.30 adrenal gland:0.83 pancreas:- breast:0.81 salivary:-

Gene Information

IDs

Refseq ID NM_016657
Gene ID 11015
Unigene ID -
Probe set ID 207264_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000100196
GTEx ID ENSG00000100196

Orthologous Gene

Mouse[1]  NM_134090
Rat[1]  NM_001127546

Chromosomal Region

22q13.1  [38,864,067  -  38,879,452]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

8125298
9118249
10591208
11827452
12477932
12529303
15461802
15489334
21139048

Gene Ontology  (GO ID)

Biological Process

GO:0006987  activation of signaling protein activity involved in unfolded protein response
GO:0044267  cellular protein metabolic process
GO:0030968  endoplasmic reticulum unfolded protein response
GO:0006621  protein retention in ER lumen
GO:0015031  protein transport
GO:0016192  vesicle-mediated transport

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane

Molecular Function

GO:0046923  ER retention sequence binding