RAB35, member RAS oncogene family

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Synonym

GTP-binding protein RAY, RAY, RAB35, member RAS oncogene family, RAB1C, RAB35, Ras-related protein Rab-35, H-ray, Rab-1C

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:3.98 cerebellum:3.90 brain stem:4.08 corpus callosum/glia:3.94 pineal gland:- peripheral nerve:3.86 spine:3.78 retina:- eye:- artery/aorta:3.76 vein:3.87 lymphnode:3.65 peripheral blood:- spleen:3.93 thymus:4.24 bone marrow:3.78 adipose:3.87 bone:- skin:4.02
CAGE cerebrum:2.95 cerebellum:- brain stem:3.13 corpus callosum/glia:3.22 pineal gland:1.85 peripheral nerve:- spine:2.67 retina:- eye:- artery/aorta:3.15 vein:3.45 lymphnode:3.46 peripheral blood:- spleen:3.50 thymus:3.40 bone marrow:- adipose:3.58 bone:- skin:-
RNA-seq cerebrum:0.13 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.34 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.90 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:3.85 placenta:4.05 prostate:3.79 ovary:3.88 testis:3.73 heart:3.91 muscle:3.95 esophagus:3.97 stomach:3.79 intestine:3.91 colon:4.07 liver/hepato:3.73 lung:3.86 bladder:- kidney:3.77 pituitary:3.80 thyroid/parathyroid:3.52 adrenal gland:3.79 pancreas:3.78 breast:3.57 salivary:3.77
CAGE uterus:3.19 placenta:3.66 prostate:3.30 ovary:3.20 testis:2.74 heart:2.97 muscle:2.67 esophagus:3.54 stomach:- intestine:3.22 colon:3.03     liver/hepato:3.29    lung:3.23 bladder:3.27 kidney:3.27 pituitary:2.68 thyroid/parathyroid:2.82 adrenal gland:- pancreas:2.94 breast:2.91 salivary:2.80
RNA-seq uterus:- placenta:- prostate:0.19 ovary:0.99 testis:0.16 heart:0.18 muscle:0.26 esophagus:- stomach:- intestine:- colon:0.82     liver/hepato:0.00        lung:0.41    bladder:- kidney:0.48 pituitary:- thyroid/parathyroid:0.26 adrenal gland:0.06 pancreas:- breast:0.63 salivary:-

Gene Information

IDs

Refseq ID NM_001167606
Gene ID 11021
Unigene ID -
Probe set ID 205461_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000111737
GTEx ID ENSG00000111737

Orthologous Gene

Mouse[1]  NM_198163
Rat[1]  NM_001013046

Chromosomal Region

12q24.23  [120,532,899  -  120,555,306]

Gene Family (Interpro ID)

IPR002041  Ran GTPase
IPR013753  Ras
IPR001806  Ras GTPase
IPR020849  Ras small GTPase
IPR003579  Ras small GTPase, Rab type
IPR005225  Small GTP-binding protein
IPR020851  Small GTPase
IPR003578  Small GTPase, Rho type

Link to Pubmed  (Pubmed ID)

7811277
12477932
14702039
14968112
15342556
15489334
16169070
16541075
16600182
16950109
17081065
18448665
18450757
18976975
19056867
19717423
19729655
19738201
20360680
20379614
20877624
21139048
21565611
21674799
21706022
21832049
21853274
21906983
21963094
21987572
22065758
22072793
22178446
22226746
22505724
23000965
23246001
23264734
23353182
24250222
24255178
24332808
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0000910  cytokinesis
GO:0016197  endosome transport
GO:0006184  GTP catabolic process
GO:0008104  protein localization
GO:0015031  protein transport
GO:0007264  small GTPase mediated signal transduction

Cellular Component

GO:0031253  cell projection membrane
GO:0045334  clathrin-coated endocytic vesicle
GO:0005905  coated pit
GO:0005768  endosome
GO:0045171  intercellular bridge
GO:0042470  melanosome
GO:0005739  mitochondrion
GO:0005886  plasma membrane

Molecular Function

GO:0019003  GDP binding
GO:0005525  GTP binding
GO:0003924  GTPase activity
GO:0005546  phosphatidylinositol-4,5-bisphosphate binding