leucine zipper, putative tumor suppressor 1

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Synonym

leucine zipper, putative tumor suppressor 1, Fez1, F37, Leucine zipper putative tumor suppressor 1, LZTS1, FEZ1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:41.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:29.40 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:25.80 bone marrow:19.70 adipose:- bone:- skin:28.80
GeneChip cerebrum:4.81 cerebellum:3.77 brain stem:3.75 corpus callosum/glia:4.17 pineal gland:- peripheral nerve:4.54 spine:3.63 retina:- eye:- artery/aorta:3.79 vein:3.71 lymphnode:3.70 peripheral blood:- spleen:3.43 thymus:3.81 bone marrow:3.54 adipose:3.73 bone:- skin:4.05
CAGE cerebrum:2.48 cerebellum:- brain stem:1.60 corpus callosum/glia:1.80 pineal gland:0.43 peripheral nerve:- spine:0.55 retina:- eye:- artery/aorta:1.16 vein:0.59 lymphnode:1.25 peripheral blood:- spleen:0.32 thymus:0.88 bone marrow:- adipose:0.71 bone:- skin:-
RNA-seq cerebrum:2.23 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.86 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.92 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:18.20 prostate:22.50 ovary:- testis:13 heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:20.80 pituitary:116 thyroid/parathyroid:- adrenal gland:50.80 pancreas:- breast:- salivary:-
GeneChip uterus:3.82 placenta:4.17 prostate:3.80 ovary:3.60 testis:5.13 heart:3.69 muscle:3.81 esophagus:3.93 stomach:3.58 intestine:3.69 colon:3.62 liver/hepato:3.55 lung:3.81 bladder:- kidney:3.64 pituitary:3.65 thyroid/parathyroid:3.76 adrenal gland:3.87 pancreas:3.59 breast:4.51 salivary:3.75
CAGE uterus:1.38 placenta:1.71 prostate:0.97 ovary:1.69 testis:2.52 heart:1.13 muscle:1.12 esophagus:1.73 stomach:- intestine:0.57 colon:0.79     liver/hepato:0.36    lung:1.20 bladder:0.91 kidney:1.42 pituitary:0.34 thyroid/parathyroid:0.82 adrenal gland:- pancreas:1.21 breast:1.16 salivary:0.36
RNA-seq uterus:- placenta:- prostate:0.84 ovary:1.69 testis:1.86 heart:0.73 muscle:0.32 esophagus:- stomach:- intestine:- colon:0.46     liver/hepato:0.16        lung:1.38    bladder:- kidney:0.95 pituitary:- thyroid/parathyroid:0.71 adrenal gland:2.46 pancreas:- breast:1.18 salivary:-

Gene Information

IDs

Refseq ID NM_021020
Gene ID 11178
Unigene ID Hs.521432
Probe set ID 47550_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000061337
GTEx ID ENSG00000061337

Orthologous Gene

Mouse[1]  NM_199364
Rat [0]  

Chromosomal Region

8p21.3  [20,103,676  -  20,161,474]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10097140
11464283
11504921
12377406
12477932
12851677
15489334
17349584
18029348
18559591
18686028
19339270
19885841
20038947
20083228
20508983
21419475
23064961
23259602
23551011
23620142
23695671

Gene Ontology  (GO ID)

Biological Process

GO:0007049  cell cycle
GO:0010467  gene expression
GO:0045087  innate immune response
GO:0016242  negative regulation of macroautophagy
GO:0032481  positive regulation of type I interferon production
GO:0048814  regulation of dendrite morphogenesis
GO:0006355  regulation of transcription, DNA-dependent
GO:0006385  RNA elongation from RNA polymerase III promoter
GO:0006386  termination of RNA polymerase III transcription
GO:0006383  transcription from RNA polymerase III promoter
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0016324  apical plasma membrane
GO:0030054  cell junction
GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0043198  dendritic shaft
GO:0043197  dendritic spine
GO:0005794  Golgi apparatus
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus
GO:0005886  plasma membrane
GO:0014069  postsynaptic density
GO:0045211  postsynaptic membrane

Molecular Function

GO:0003677  DNA binding
GO:0005515  protein binding
GO:0003700  transcription factor activity