SP140 nuclear body protein

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Synonym

SP140, LYSP100, MGC126440, LYSP100-B, SP140 nuclear body protein, LYSp100 protein, Lymphoid-restricted homolog of Sp100, Speckled 140 kDa, Nuclear body protein SP140, LYSP100-A, Nuclear autoantigen Sp-140

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:5.90 artery/aorta:60 vein:- lymphnode:131.40 peripheral blood:- spleen:37.80 thymus:- bone marrow:196.80 adipose:- bone:- skin:19.20
GeneChip nodata
CAGE cerebrum:0.46 cerebellum:- brain stem:1.00 corpus callosum/glia:0.63 pineal gland:0.62 peripheral nerve:- spine:1.24 retina:- eye:- artery/aorta:1.33 vein:3.88 lymphnode:3.93 peripheral blood:- spleen:4.05 thymus:1.89 bone marrow:- adipose:1.51 bone:- skin:-
RNA-seq cerebrum:0.03 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:1.27 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.07 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:- prostate:- ovary:- testis:38.90 heart:- muscle:- esophagus:- stomach:42.50 intestine:- colon:8.50     liver/hepato:-        lung:14.70    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:18.60 salivary:-
GeneChip nodata
CAGE uterus:0.73 placenta:0.68 prostate:1.06 ovary:0.64 testis:0.50 heart:0.43 muscle:0.24 esophagus:1.93 stomach:- intestine:1.84 colon:1.60     liver/hepato:0.96    lung:2.53 bladder:2.25 kidney:0.95 pituitary:1.22 thyroid/parathyroid:0.60 adrenal gland:- pancreas:0 breast:1.16 salivary:1.89
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.07 testis:0.00 heart:0.00 muscle:0.30 esophagus:- stomach:- intestine:- colon:0.19     liver/hepato:0.37        lung:1.97    bladder:- kidney:0.20 pituitary:- thyroid/parathyroid:0 adrenal gland:1.22 pancreas:- breast:0.40 salivary:-

Gene Information

IDs

Refseq ID NM_001005176
Gene ID 11262
Unigene ID Hs.632549
Probe set ID -
Ensembl ID ENSG00000079263
GTEx ID ENSG00000079263

Orthologous Gene

Mouse[6]  NM_001037909, NM_175219, NM_001013817, NM_213615
Rat[1]  NM_001012133, NM_175219, NM_001013817, NM_213615

Chromosomal Region

2q37.1  [231,090,444  -  231,223,762]

Gene Family (Interpro ID)

IPR000770  SAND
IPR010919  SAND-like
IPR019787  Zinc finger, PHD-finger
IPR001965  Zinc finger, PHD-type

Link to Pubmed  (Pubmed ID)

8695863
8910577
11331592
12368356
12477932
12887892
18029348
18758461
19149577
20332261
20731705
21102463
21833088
22505724
22700719
23128233
23770605
24292274

Gene Ontology  (GO ID)

Biological Process

GO:0006952  defense response
GO:0006355  regulation of transcription, DNA-dependent

Cellular Component

GO:0005737  cytoplasm
GO:0005635  nuclear envelope
GO:0005730  nucleolus
GO:0005654  nucleoplasm
GO:0005634  nucleus

Molecular Function

GO:0003677  DNA binding
GO:0003700  transcription factor activity
GO:0008270  zinc ion binding