1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta)

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Synonym

LPAATZ, 1-AGP acyltransferase 6, Lysophosphatidic acid acyltransferase-zeta, AGPAT6, LPAAT-zeta, DKFZp586M1819, UNQ551/PRO1108, TSARG7, 1-AGPAT 6

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:28.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:- eye:88.20 artery/aorta:- vein:66.60 lymphnode:40.40 peripheral blood:36.40 spleen:18.90 thymus:25.80 bone marrow:39.40 adipose:40.30 bone:12.80 skin:48
GeneChip nodata
CAGE cerebrum:3.16 cerebellum:- brain stem:3.24 corpus callosum/glia:3.38 pineal gland:2.97 peripheral nerve:- spine:3.15 retina:- eye:- artery/aorta:3.02 vein:2.57 lymphnode:2.89 peripheral blood:- spleen:2.99 thymus:2.83 bone marrow:- adipose:2.81 bone:- skin:-
RNA-seq cerebrum:2.63 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.35 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.17 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:27.30 placenta:65.60 prostate:67.60 ovary:186.30 testis:21.60 heart:12.80 muscle:60.30 esophagus:- stomach:42.50 intestine:64.80 colon:110.20     liver/hepato:21.10        lung:39.10    bladder:- kidney:83.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:46.50 salivary:-
GeneChip nodata
CAGE uterus:3.15 placenta:3.30 prostate:2.80 ovary:2.78 testis:3.03 heart:2.91 muscle:3.32 esophagus:2.55 stomach:- intestine:2.57 colon:2.78     liver/hepato:3.30    lung:3.02 bladder:2.75 kidney:3.20 pituitary:3.27 thyroid/parathyroid:2.86 adrenal gland:- pancreas:2.98 breast:2.87 salivary:3.24
RNA-seq uterus:- placenta:- prostate:2.90 ovary:3.08 testis:3.04 heart:2.42 muscle:2.62 esophagus:- stomach:- intestine:- colon:2.52     liver/hepato:3.53        lung:2.97    bladder:- kidney:3.58 pituitary:- thyroid/parathyroid:3.43 adrenal gland:3.35 pancreas:- breast:3.07 salivary:-

Gene Information

IDs

Refseq ID NM_178819
Gene ID 137964
Unigene ID Hs.355753
Probe set ID -
Ensembl ID ENSG00000158669
GTEx ID ENSG00000158669

Orthologous Gene

Mouse[2]  NM_018743
Rat[1]  NM_001047849

Chromosomal Region

8p11.21  [41,434,706  -  41,482,520]

Gene Family (Interpro ID)

IPR002123  Phospholipid/glycerol acyltransferase

Link to Pubmed  (Pubmed ID)

8944226
12477932
12938015
12975309
15489334
16625827
16713569
18238778
20181984
21906983
21988832

Gene Ontology  (GO ID)

Biological Process

GO:0006637  acyl-CoA metabolic process
GO:0016024  CDP-diacylglycerol biosynthetic process
GO:0044255  cellular lipid metabolic process
GO:0046339  diacylglycerol metabolic process
GO:0006631  fatty acid metabolic process
GO:0002071  glandular epithelial cell maturation
GO:0046474  glycerophospholipid biosynthetic process
GO:0007595  lactation
GO:0008610  lipid biosynthetic process
GO:0006654  phosphatidic acid biosynthetic process
GO:0006656  phosphatidylcholine biosynthetic process
GO:0006644  phospholipid metabolic process
GO:0040014  regulation of multicellular organism growth
GO:0019432  triglyceride biosynthetic process

Cellular Component

GO:0005783  endoplasmic reticulum
GO:0005789  endoplasmic reticulum membrane
GO:0016021  integral to membrane
GO:0016020  membrane

Molecular Function

GO:0003841  1-acylglycerol-3-phosphate O-acyltransferase activity
GO:0004366  glycerol-3-phosphate O-acyltransferase activity