TruB pseudouridine (psi) synthase homolog 1 (E. coli)

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Synonym

PUS4, TRUB1, Probable tRNA pseudouridine synthase 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:3.21 cerebellum:- brain stem:3.17 corpus callosum/glia:2.87 pineal gland:3.05 peripheral nerve:- spine:2.80 retina:- eye:- artery/aorta:2.61 vein:2.70 lymphnode:2.62 peripheral blood:- spleen:2.87 thymus:2.98 bone marrow:- adipose:2.52 bone:- skin:-
RNA-seq cerebrum:3.63 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.44 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.67 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:11.30 ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:- salivary:-
GeneChip nodata
CAGE uterus:2.69 placenta:2.35 prostate:2.97 ovary:3.18 testis:3.59 heart:2.53 muscle:2.30 esophagus:2.80 stomach:- intestine:2.42 colon:2.60     liver/hepato:3.01    lung:2.50 bladder:2.70 kidney:3.26 pituitary:3.10 thyroid/parathyroid:2.85 adrenal gland:- pancreas:2.66 breast:1.16 salivary:2.90
RNA-seq uterus:- placenta:- prostate:2.91 ovary:3.52 testis:4.18 heart:2.73 muscle:1.73 esophagus:- stomach:- intestine:- colon:2.34     liver/hepato:2.63        lung:1.66    bladder:- kidney:3.40 pituitary:- thyroid/parathyroid:2.78 adrenal gland:2.64 pancreas:- breast:3.01 salivary:-

Gene Information

IDs

Refseq ID NM_139169
Gene ID 142940
Unigene ID Hs.211870
Probe set ID -
Ensembl ID ENSG00000165832
GTEx ID ENSG00000165832

Orthologous Gene

Mouse[2]  NM_028115, NM_029839
Rat[1]  NM_001012173, NM_029839

Chromosomal Region

10q25.3  [116,697,952  -  116,737,430]

Gene Family (Interpro ID)

IPR002501  Pseudouridine synthase II, TruB, N-terminal
IPR014780  Pseudouridine synthase II, TruB, N-terminal, bacterial-type
IPR020103  Pseudouridine synthase, catalytic domain

Link to Pubmed  (Pubmed ID)

8125298
12477932
12736709
15164054
15489334
16385451
19471022
21139048
21145461
21832049
23940030
24250222
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0001522  pseudouridine synthesis
GO:0008033  tRNA processing

Molecular Function

GO:0009982  pseudouridine synthase activity
GO:0003723  RNA binding