cathepsin L2

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Synonym

cathepsin L2, UNQ268/PRO305, CTSU, CTSV, CTSL2, MGC125957, Cathepsin V, Cathepsin U, CATL2, Cathepsin L2 precursor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.69 cerebellum:5.60 brain stem:5.81 corpus callosum/glia:6.11 pineal gland:- peripheral nerve:5.25 spine:5.82 retina:- eye:- artery/aorta:5.31 vein:5.76 lymphnode:5.42 peripheral blood:- spleen:5.04 thymus:10.70 bone marrow:5.75 adipose:5.64 bone:- skin:7.39
CAGE cerebrum:0.64 cerebellum:- brain stem:1.54 corpus callosum/glia:1.72 pineal gland:0.83 peripheral nerve:- spine:1.03 retina:- eye:- artery/aorta:0.59 vein:4.67 lymphnode:0.81 peripheral blood:- spleen:0 thymus:5.86 bone marrow:- adipose:0.78 bone:- skin:-
RNA-seq cerebrum:0.29 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.01 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.00 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:5.88 placenta:6.86 prostate:5.43 ovary:5.78 testis:8.59 heart:5.56 muscle:5.69 esophagus:6.71 stomach:5.37 intestine:5.70 colon:5.78 liver/hepato:5.57 lung:5.68 bladder:- kidney:6.89 pituitary:5.50 thyroid/parathyroid:5.58 adrenal gland:5.28 pancreas:5.99 breast:6.24 salivary:5.62
CAGE uterus:1.91 placenta:3.12 prostate:0.53 ovary:0.32 testis:4.48 heart:0.03 muscle:0.38 esophagus:2.89 stomach:- intestine:0.57 colon:0.56     liver/hepato:0.36    lung:0.54 bladder:0 kidney:2.38 pituitary:0.52 thyroid/parathyroid:0.64 adrenal gland:- pancreas:0.58 breast:1.16 salivary:1.00
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:2.91 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.46 pituitary:- thyroid/parathyroid:0.00 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_001333
Gene ID 1515
Unigene ID -
Probe set ID 210074_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000136943
GTEx ID ENSG00000136943

Orthologous Gene

Mouse[1]  NM_009984
Rat [0]  

Chromosomal Region

9q22.33  [99,794,940  -  99,801,925]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

9563472
9727401
10029531
10382972
11027133
12477932
12648222
12925692
15164053
15192101
15489334
15679121
16565075
17516850
17869649
17889653
18163891
19939935
20347002
20536394
21139048
22393040
22452389
22562303
22967898
23287360
23542171
24121514

Gene Ontology  (GO ID)

Biological Process

GO:0019886  antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0048102  autophagic cell death
GO:0009267  cellular response to starvation
GO:0046697  decidualization
GO:0022617  extracellular matrix disassembly
GO:0030198  extracellular matrix organization
GO:0010259  multicellular organismal aging
GO:0021675  nerve development
GO:0006508  proteolysis
GO:0051384  response to glucocorticoid stimulus
GO:0009749  response to glucose stimulus
GO:0034698  response to gonadotropin stimulus
GO:0060008  Sertoli cell differentiation
GO:0007283  spermatogenesis

Cellular Component

GO:0009897  external side of plasma membrane
GO:0005576  extracellular region
GO:0043202  lysosomal lumen
GO:0005902  microvillus
GO:0043005  neuron projection
GO:0043204  perikaryon

Molecular Function

GO:0004177  aminopeptidase activity
GO:0004197  cysteine-type endopeptidase activity
GO:0008234  cysteine-type peptidase activity
GO:0030984  kininogen binding
GO:0042277  peptide binding
GO:0032403  protein complex binding