adrenergic, beta-3-, receptor

Synonym

ADRB3R, Beta-3 adrenoreceptor, Beta-3 adrenoceptor, B3AR, ADRB3, BETA3AR, Beta-3 adrenergic receptor, adrenergic, beta-3-, receptor

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:11.80

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:12.90

bone marrow:-

adipose:-

bone:-

skin:-

GeneChip

cerebrum:4.45

cerebellum:4.44

brain stem:4.64

corpus callosum/glia:4.27

pineal gland:-

peripheral nerve:4.12

spine:4.14

retina:-

eye:-

artery/aorta:4.27

vein:4.45

lymphnode:4.14

peripheral blood:-

spleen:4.06

thymus:4.26

bone marrow:4.18

adipose:4.26

bone:-

skin:4.52

CAGE

cerebrum:0.17

cerebellum:-

brain stem:0.03

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0

vein:0.96

lymphnode:0

peripheral blood:-

spleen:0

thymus:0

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.04

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.02

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:9.10

placenta:25.50

prostate:11.30

ovary:111.80

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.26

placenta:4.05

prostate:4.27

ovary:4.38

testis:4.15

heart:4.15

muscle:4.65

esophagus:4.42

stomach:4.24

intestine:4.44

colon:4.27

liver/hepato:4.33

lung:4.38

bladder:-

kidney:4.24

pituitary:4.33

thyroid/parathyroid:4.12

adrenal gland:4.13

pancreas:4.59

breast:4.16

salivary:4.35

CAGE

uterus:0.76

placenta:1.11

prostate:1.61

ovary:2.42

testis:0.19

heart:0.03

muscle:0

esophagus:1.01

stomach:-

intestine:0.73

colon:0.69

liver/hepato:0

lung:0.10

bladder:2.25

kidney:0

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:1.81

ovary:3.11

testis:0.16

heart:0.02

muscle:0

esophagus:-

stomach:-

intestine:-

colon:0.50

liver/hepato:0

lung:0

bladder:-

kidney:0.07

pituitary:-

thyroid/parathyroid:0

adrenal gland:0.02

pancreas:-

breast:0.26

salivary:-

IDs

Refseq ID	NM_000025
Gene ID	155
Unigene ID	Hs.2549
Probe set ID	217303_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000188778
GTEx ID	ENSG00000188778

Orthologous Gene

Mouse[2]	NM_013462
Rat [0]

Chromosomal Region

8p11.23 [37,820,516 - 37,824,483]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR002232	5-Hydroxytryptamine 6 receptor
IPR000276	7TM GPCR, rhodopsin-like
IPR002233	Adrenergic receptor
IPR000681	Adrenergic receptor, beta 3
IPR017452	GPCR, rhodopsin-like superfamily

Gene Ontology (GO ID)

Biological Process

GO:0007190	activation of adenylate cyclase activity
GO:0007189	activation of adenylate cyclase activity by G-protein signaling pathway
GO:0007568	aging
GO:0050873	brown fat cell differentiation
GO:0005975	carbohydrate metabolic process
GO:0002032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin
GO:0002024	diet induced thermogenesis
GO:0042755	eating behavior
GO:0006112	energy reserve metabolic process
GO:0007188	G-protein signaling, coupled to cAMP nucleotide second messenger
GO:0007187	G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0006091	generation of precursor metabolites and energy
GO:0031649	heat generation
GO:0040015	negative regulation of multicellular organism growth
GO:0043410	positive regulation of MAPKKK cascade
GO:0006898	receptor-mediated endocytosis
GO:0046677	response to antibiotic
GO:0009409	response to cold
GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure

Cellular Component

GO:0005887	integral to plasma membrane
GO:0005634	nucleus
GO:0005886	plasma membrane
GO:0043235	receptor complex

Molecular Function

GO:0031699	beta-3 adrenergic receptor binding
GO:0004939	beta-adrenergic receptor activity
GO:0015052	beta3-adrenergic receptor activity
GO:0051379	epinephrine binding
GO:0051380	norepinephrine binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity

adrenergic, beta-3-, receptor

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function