adenylosuccinate synthase

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Synonym

AMPSase 2, adenylosuccinate synthase, ADSS2, ADEH, AdSS 2, MGC20404, IMP--aspartate ligase 2, ADSS, Adenylosuccinate synthetase, acidic isozyme, Adenylosuccinate synthetase isozyme 2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:93.60 cerebellum:25.20 brain stem:- corpus callosum/glia:262.50 pineal gland:- peripheral nerve:92 spine:- retina:237.30 eye:94 artery/aorta:509.60 vein:199.90 lymphnode:141.50 peripheral blood:127.50 spleen:170.20 thymus:90.20 bone marrow:137.80 adipose:- bone:89.60 skin:105.60
GeneChip nodata
CAGE cerebrum:3.83 cerebellum:- brain stem:4.55 corpus callosum/glia:4.47 pineal gland:3.18 peripheral nerve:- spine:4.00 retina:- eye:- artery/aorta:4.00 vein:3.95 lymphnode:3.95 peripheral blood:- spleen:4.06 thymus:3.99 bone marrow:- adipose:3.87 bone:- skin:-
RNA-seq nodata
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:136.70 placenta:40.10 prostate:135.20 ovary:- testis:199 heart:89.40 muscle:40.20 esophagus:- stomach:42.50 intestine:97.20 colon:25.40     liver/hepato:21.10        lung:112.40    bladder:251.20 kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:80 breast:27.90 salivary:-
GeneChip nodata
CAGE uterus:3.89 placenta:3.85 prostate:3.90 ovary:3.90 testis:4.07 heart:3.22 muscle:2.87 esophagus:4.02 stomach:- intestine:3.99 colon:3.83     liver/hepato:3.70    lung:4.02 bladder:4.15 kidney:3.99 pituitary:3.81 thyroid/parathyroid:3.72 adrenal gland:- pancreas:3.85 breast:3.78 salivary:3.42
RNA-seq nodata

Gene Information

IDs

Refseq ID NM_001126000
Gene ID 159
Unigene ID Hs.498313
Probe set ID -
Ensembl ID -
GTEx ID -

Orthologous Gene

Mouse [0]  
Rat [0]  

Chromosomal Region

1q44  [244,571,796  -  244,615,436]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

648524
1574589
1592113
2004783
4436310
8887278
12477932
15489334
15786719
18029348
18469177
18721483
19115993
20562859
21139048
21145461
21890473
21906983
22505724
22863883
22939629
23000965
23251661
23455924
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0044208  'de novo' AMP biosynthetic process
GO:0006167  AMP biosynthetic process
GO:0006531  aspartate metabolic process
GO:0071257  cellular response to electrical stimulus
GO:0006184  GTP catabolic process
GO:0002376  immune system process
GO:0046040  IMP metabolic process
GO:0055086  nucleobase, nucleoside and nucleotide metabolic process
GO:0006144  purine base metabolic process
GO:0009168  purine ribonucleoside monophosphate biosynthetic process
GO:0060359  response to ammonium ion
GO:0014074  response to purine

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005886  plasma membrane

Molecular Function

GO:0004019  adenylosuccinate synthase activity
GO:0005525  GTP binding
GO:0000287  magnesium ion binding
GO:0042301  phosphate binding