BMP binding endothelial regulator

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Synonym

Protein crossveinless-2, hCV2, CV2, CV-2, CRIM3, BMPER, BMP binding endothelial regulator

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:1.86 cerebellum:- brain stem:1.27 corpus callosum/glia:1.04 pineal gland:0.57 peripheral nerve:- spine:1.18 retina:- eye:- artery/aorta:1.22 vein:2.01 lymphnode:1.38 peripheral blood:- spleen:0.09 thymus:0.57 bone marrow:- adipose:1.16 bone:- skin:-
RNA-seq cerebrum:1.66 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.13 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.70 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:1.84 placenta:1.71 prostate:1.21 ovary:1.41 testis:0.66 heart:1.64 muscle:1.23 esophagus:0.86 stomach:- intestine:1.89 colon:1.17     liver/hepato:2.78    lung:2.16 bladder:1.27 kidney:0.44 pituitary:1.87 thyroid/parathyroid:0.37 adrenal gland:- pancreas:0 breast:1.16 salivary:1.00
RNA-seq uterus:- placenta:- prostate:1.44 ovary:1.59 testis:0.94 heart:0.36 muscle:0.54 esophagus:- stomach:- intestine:- colon:0.94     liver/hepato:1.43        lung:1.78    bladder:- kidney:0.14 pituitary:- thyroid/parathyroid:0.50 adrenal gland:3.67 pancreas:- breast:1.02 salivary:-

Gene Information

IDs

Refseq ID NM_133468
Gene ID 168667
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000164619
GTEx ID ENSG00000164619

Orthologous Gene

Mouse[1]  NM_028472
Rat[1]  NM_001135799

Chromosomal Region

7p14.3  [33,944,523  -  34,195,484]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

11853319
12477932
12690205
12897139
14702039
14766204
15489334
16344560
18787191
20869035
21990102
22020334
22474252
22772758
22778264
23641068

Gene Ontology  (GO ID)

Biological Process

GO:0002043  blood vessel endothelial cell proliferation during sprouting angiogenesis
GO:0042118  endothelial cell activation
GO:0048839  inner ear development
GO:0030514  negative regulation of BMP signaling pathway
GO:0070374  positive regulation of ERK1 and ERK2 cascade
GO:0010594  regulation of endothelial cell migration
GO:0060393  regulation of pathway-restricted SMAD protein phosphorylation
GO:0001657  ureteric bud development

Cellular Component

GO:0005615  extracellular space