deoxyribonuclease I-like 1

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Synonym

Muscle-specific DNase I-like, XIB, Deoxyribonuclease I-like 1 precursor, DNase I-like 1, DNAS1L1, DNase X, deoxyribonuclease I-like 1, DNASE1L1, DNL1L

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:7.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:61.30 spine:- retina:118.60 eye:47 artery/aorta:30 vein:- lymphnode:- peripheral blood:91.10 spleen:18.90 thymus:- bone marrow:19.70 adipose:- bone:25.60 skin:24
GeneChip cerebrum:6.31 cerebellum:5.95 brain stem:6.28 corpus callosum/glia:6.01 pineal gland:- peripheral nerve:6.33 spine:6.26 retina:- eye:- artery/aorta:6.89 vein:6.40 lymphnode:6.70 peripheral blood:- spleen:6.94 thymus:6.05 bone marrow:6.71 adipose:6.74 bone:- skin:6.53
CAGE cerebrum:2.24 cerebellum:- brain stem:2.08 corpus callosum/glia:2.19 pineal gland:2.36 peripheral nerve:- spine:2.25 retina:- eye:- artery/aorta:3.28 vein:2.91 lymphnode:2.99 peripheral blood:- spleen:3.13 thymus:1.92 bone marrow:- adipose:3.15 bone:- skin:-
RNA-seq cerebrum:0.77 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.82 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.07 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:47.40 prostate:- ovary:- testis:17.30 heart:12.80 muscle:80.40 esophagus:- stomach:- intestine:32.40 colon:33.90     liver/hepato:-        lung:19.60    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:9.30 salivary:-
GeneChip uterus:6.45 placenta:6.71 prostate:6.78 ovary:6.36 testis:5.96 heart:7.18 muscle:8.57 esophagus:7 stomach:6.52 intestine:6.69 colon:6.59 liver/hepato:6.61 lung:6.96 bladder:- kidney:6.82 pituitary:6.74 thyroid/parathyroid:6.89 adrenal gland:6.77 pancreas:6.48 breast:6.51 salivary:6.63
CAGE uterus:2.65 placenta:3.06 prostate:2.49 ovary:2.49 testis:2.22 heart:3.26 muscle:4.39 esophagus:2.86 stomach:- intestine:2.90 colon:2.90     liver/hepato:2.75    lung:3.18 bladder:2.46 kidney:3.07 pituitary:2.57 thyroid/parathyroid:2.76 adrenal gland:- pancreas:2.76 breast:2.91 salivary:2.80
RNA-seq uterus:- placenta:- prostate:0.22 ovary:0.40 testis:0.28 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.50     liver/hepato:0.69        lung:0.23    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.58 adrenal gland:0.00 pancreas:- breast:0.01 salivary:-

Gene Information

IDs

Refseq ID NM_001009934
Gene ID 1774
Unigene ID Hs.401929
Probe set ID 203912_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000013563
GTEx ID ENSG00000013563

Orthologous Gene

Mouse[1]  NM_001172154, NM_027109
Rat[1]  NM_001014223, NM_027109

Chromosomal Region

Xq28  [153,629,579  -  153,640,449]

Gene Family (Interpro ID)

IPR008185  Deoxyribonuclease I, eukaryotic
IPR016202  Deoxyribonuclease I-like

Link to Pubmed  (Pubmed ID)

8248200
8541839
8654957
8733135
9205125
10409440
11076863
11256614
12477932
15146197
15489334
15489336
15772651
16107205
16381901
17180083
19913121
20503202
20628086
20967767
24098122
24304513
24329527

Gene Ontology  (GO ID)

Biological Process

GO:0006308  DNA catabolic process
GO:0006259  DNA metabolic process

Cellular Component

GO:0005783  endoplasmic reticulum

Molecular Function

GO:0004536  deoxyribonuclease activity
GO:0003677  DNA binding
GO:0016888  endodeoxyribonuclease activity, producing 5'-phosphomonoesters