extracellular matrix protein 1

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Synonym

Secretory component p85, ECM1, extracellular matrix protein 1, Extracellular matrix protein 1 precursor

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:52.10 cerebellum:12.60 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:76.40 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:72.90 spleen:208 thymus:25.80 bone marrow:- adipose:282.30 bone:473.40 skin:283.20
GeneChip cerebrum:6.36 cerebellum:6.32 brain stem:6.35 corpus callosum/glia:6.18 pineal gland:- peripheral nerve:7.16 spine:6.01 retina:- eye:- artery/aorta:7.24 vein:7.80 lymphnode:7.73 peripheral blood:- spleen:6.26 thymus:5.57 bone marrow:6.12 adipose:7.35 bone:- skin:8.35
CAGE cerebrum:2.44 cerebellum:- brain stem:2.51 corpus callosum/glia:1.76 pineal gland:2.47 peripheral nerve:- spine:1.90 retina:- eye:- artery/aorta:3.73 vein:3.90 lymphnode:4.25 peripheral blood:- spleen:3.63 thymus:1.29 bone marrow:- adipose:5.09 bone:- skin:-
RNA-seq cerebrum:0.00 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.00 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.30 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:309.80 placenta:375.20 prostate:112.60 ovary:149.10 testis:129.80 heart:178.80 muscle:- esophagus:2056.90 stomach:106.20 intestine:226.80 colon:25.40     liver/hepato:31.70        lung:73.30    bladder:- kidney:10.40 pituitary:- thyroid/parathyroid:- adrenal gland:355.50 pancreas:26.70 breast:46.50 salivary:-
GeneChip uterus:8.08 placenta:8.42 prostate:6.35 ovary:6.62 testis:5.92 heart:7.30 muscle:6.28 esophagus:11.45 stomach:6.75 intestine:6.83 colon:7.27 liver/hepato:7.35 lung:6.84 bladder:- kidney:6.18 pituitary:6.40 thyroid/parathyroid:6.35 adrenal gland:7.12 pancreas:6.52 breast:7.44 salivary:5.93
CAGE uterus:4.87 placenta:5.18 prostate:3.42 ovary:3.49 testis:3.76 heart:4.70 muscle:3.13 esophagus:7.79 stomach:- intestine:3.04 colon:3.48     liver/hepato:4.92    lung:3.37 bladder:4.12 kidney:2.99 pituitary:2.55 thyroid/parathyroid:2.79 adrenal gland:- pancreas:1.74 breast:4.73 salivary:2.63
RNA-seq uterus:- placenta:- prostate:0.00 ovary:0.00 testis:0.00 heart:0.00 muscle:0.00 esophagus:- stomach:- intestine:- colon:0.00     liver/hepato:0.00        lung:0.00    bladder:- kidney:0.00 pituitary:- thyroid/parathyroid:0.03 adrenal gland:0.00 pancreas:- breast:0.00 salivary:-

Gene Information

IDs

Refseq ID NM_022664
Gene ID 1893
Unigene ID Hs.81071
Probe set ID 209365_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000143369
GTEx ID ENSG00000143369

Orthologous Gene

Mouse[1]  NM_007899
Rat [0]  

Chromosomal Region

1q21.3  [150,480,538  -  150,486,265]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

601588
9367673
9501329
10733679
11165938
11292659
11929856
12477932
12603844
12604605
12761501
14550953
14702039
15990087
16274456
16335952
16344560
16512877
16646403
16713569
17721643
17927570
18200062
18438406
18443958
19068216
19199708
19219685
19230975
19275936
19519837
19521735
19734986
19861958
20014019
20805453
20870722
21128013
21139048
21349189
21791056
21988832
22489696
23602568
23682690
23696932
24023917
24163370
24259048

Gene Ontology  (GO ID)

Biological Process

GO:0001525  angiogenesis
GO:0031214  biomineral formation
GO:0006954  inflammatory response
GO:0030502  negative regulation of bone mineralization
GO:0001960  negative regulation of cytokine-mediated signaling pathway
GO:0010466  negative regulation of peptidase activity
GO:0001503  ossification
GO:0045766  positive regulation of angiogenesis
GO:0001938  positive regulation of endothelial cell proliferation
GO:0043123  positive regulation of I-kappaB kinase/NF-kappaB cascade
GO:0002828  regulation of T-helper 2 type immune response
GO:0006357  regulation of transcription from RNA polymerase II promoter
GO:0007165  signal transduction

Cellular Component

GO:0031012  extracellular matrix
GO:0005615  extracellular space
GO:0005578  proteinaceous extracellular matrix

Molecular Function

GO:0019899  enzyme binding
GO:0005134  interleukin-2 receptor binding
GO:0043236  laminin binding
GO:0002020  protease binding
GO:0005515  protein binding
GO:0008022  protein C-terminus binding
GO:0004871  signal transducer activity