Rho GTPase activating protein 27

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Synonym

Rho GTPase activating protein 27, CAMGAP1, MGC120624, FLJ43547, ARHGAP27

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:-
GeneChip nodata
CAGE cerebrum:1.97 cerebellum:- brain stem:2.46 corpus callosum/glia:2.59 pineal gland:1.25 peripheral nerve:- spine:2.66 retina:- eye:- artery/aorta:2.12 vein:3.94 lymphnode:4.00 peripheral blood:- spleen:4.00 thymus:3.88 bone marrow:- adipose:2.61 bone:- skin:-
RNA-seq cerebrum:0 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:3.60 prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip nodata
CAGE uterus:2.23 placenta:2.84 prostate:2.44 ovary:1.72 testis:1.32 heart:2.63 muscle:1.15 esophagus:3.56 stomach:- intestine:4.21 colon:3.81     liver/hepato:1.54    lung:3.17 bladder:2.25 kidney:3.03 pituitary:1.65 thyroid/parathyroid:1.92 adrenal gland:- pancreas:1.98 breast:2.47 salivary:2.35
RNA-seq uterus:- placenta:- prostate:0 ovary:0 testis:0 heart:0 muscle:0 esophagus:- stomach:- intestine:- colon:0     liver/hepato:0        lung:0    bladder:- kidney:0 pituitary:- thyroid/parathyroid:0 adrenal gland:0 pancreas:- breast:0 salivary:-

Gene Information

IDs

Refseq ID NM_199282
Gene ID 201176
Unigene ID Hs.463165
Probe set ID -
Ensembl ID ENSG00000159314
ENSG00000257961
GTEx ID ENSG00000159314
ENSG00000257961

Orthologous Gene

Mouse[2]  NM_001205236, NM_133715, NM_183288
Rat[1]  NM_198759, NM_133715, NM_183288

Chromosomal Region

HSCHR17_1  [43,471,268  -  43,510,270]
17q21.31  [43,471,275  -  43,511,787]

Gene Family (Interpro ID)

IPR001849  Pleckstrin homology
IPR008936  Rho GTPase activation protein
IPR000198  RhoGAP
IPR001202  WW/Rsp5/WWP

Link to Pubmed  (Pubmed ID)

11181995
12107413
12297274
12477932
14702039
15147912
15492870
20070850
21890473

Gene Ontology  (GO ID)

Biological Process

GO:0043089  positive regulation of Cdc42 GTPase activity
GO:0032855  positive regulation of Rac GTPase activity
GO:0006898  receptor-mediated endocytosis
GO:0007165  signal transduction

Cellular Component

GO:0005737  cytoplasm
GO:0005622  intracellular
GO:0016020  membrane

Molecular Function

GO:0005543  phospholipid binding
GO:0030675  Rac GTPase activator activity
GO:0017124  SH3 domain binding