aminolevulinate, delta-, synthase 2

Synonym

ALAS2, ASB, ANH1, ALASE, ALAS-E, Delta-ALA synthetase, Delta-aminolevulinate synthase, 5-aminolevulinic acid synthase, XLSA

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:20.10

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:30.70

spine:-

retina:-

eye:29.40

artery/aorta:-

vein:666.50

lymphnode:-

peripheral blood:127.50

spleen:151.30

thymus:25.80

bone marrow:39.40

adipose:-

bone:64

skin:-

GeneChip

cerebrum:4.92

cerebellum:4.90

brain stem:5.07

corpus callosum/glia:4.68

pineal gland:-

peripheral nerve:4.77

spine:4.82

retina:-

eye:-

artery/aorta:5.01

vein:5.39

lymphnode:4.78

peripheral blood:-

spleen:5.22

thymus:4.47

bone marrow:10.22

adipose:5.01

bone:-

skin:5.32

CAGE

cerebrum:0.48

cerebellum:-

brain stem:0.37

corpus callosum/glia:0.96

pineal gland:0.65

peripheral nerve:-

spine:0.79

retina:-

eye:-

artery/aorta:1.85

vein:1.23

lymphnode:0.52

peripheral blood:-

spleen:1.97

thymus:0.64

bone marrow:-

adipose:1.54

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0.00

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:112.90

prostate:-

ovary:-

testis:-

heart:178.80

muscle:120.50

esophagus:-

stomach:-

intestine:-

colon:-

liver/hepato:496.10

lung:19.60

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:-

salivary:-

GeneChip

uterus:4.69

placenta:6.82

prostate:4.66

ovary:4.83

testis:4.68

heart:4.96

muscle:5.13

esophagus:4.71

stomach:4.68

intestine:4.95

colon:5.66

liver/hepato:4.84

lung:5.13

bladder:-

kidney:4.89

pituitary:4.91

thyroid/parathyroid:4.71

adrenal gland:5.04

pancreas:5.09

breast:4.66

salivary:4.95

CAGE

uterus:0.58

placenta:4.45

prostate:1.82

ovary:2.46

testis:0.65

heart:1.62

muscle:1.76

esophagus:1.75

stomach:-

intestine:0.07

colon:0.32

liver/hepato:0.84

lung:2.00

bladder:2.60

kidney:0.08

pituitary:0.99

thyroid/parathyroid:1.88

adrenal gland:-

pancreas:1.42

breast:0.90

salivary:0.36

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.08

testis:0.22

heart:0.00

muscle:0.00

esophagus:-

stomach:-

intestine:-

colon:0.30

liver/hepato:0.00

lung:0.08

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0.00

adrenal gland:0.00

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_001037968
Gene ID	212
Unigene ID	Hs.522666
Probe set ID	211560_s_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000158578
GTEx ID	ENSG00000158578

Orthologous Gene

Mouse[2]	NM_001102446, NM_009653
Rat[2]	NM_001102446, NM_009653

Chromosomal Region

Xp11.21 [55,035,488 - 55,057,497]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

IPR004839	Aminotransferase, class I/II
IPR015424	Pyridoxal phosphate-dependent transferase, major domain
IPR010961	Tetrapyrrole biosynthesis, 5-aminolevulinic acid synthase

GO:0006879	cellular iron ion homeostasis
GO:0030218	erythrocyte differentiation
GO:0006783	heme biosynthetic process
GO:0042541	hemoglobin biosynthetic process
GO:0032364	oxygen homeostasis
GO:0006778	porphyrin metabolic process
GO:0006782	protoporphyrinogen IX biosynthetic process
GO:0001666	response to hypoxia

GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix
GO:0005739	mitochondrion

GO:0003870	5-aminolevulinate synthase activity
GO:0050662	coenzyme binding
GO:0016594	glycine binding
GO:0005515	protein binding
GO:0030170	pyridoxal phosphate binding

aminolevulinate, delta-, synthase 2

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function