prostaglandin reductase 1

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Synonym

15-oxoprostaglandin 13-reductase, LTB4DH, leukotriene B4 12-hydroxydehydrogenase, MGC34943

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:9.50 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:112.30 retina:- eye:35.30 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:80.70 bone:25.60 skin:9.60
GeneChip nodata
CAGE cerebrum:3.49 cerebellum:- brain stem:2.97 corpus callosum/glia:2.65 pineal gland:4.24 peripheral nerve:- spine:2.90 retina:- eye:- artery/aorta:3.41 vein:2.78 lymphnode:3.43 peripheral blood:- spleen:2.54 thymus:1.84 bone marrow:- adipose:4.01 bone:- skin:-
RNA-seq cerebrum:3.47 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:3.68 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.68 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:236.90 placenta:3.60 prostate:56.30 ovary:37.30 testis:- heart:76.60 muscle:- esophagus:- stomach:- intestine:32.40 colon:25.40     liver/hepato:52.80        lung:9.80    bladder:- kidney:124.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:9.30 salivary:-
GeneChip nodata
CAGE uterus:3.88 placenta:2.85 prostate:4.24 ovary:3.50 testis:3.00 heart:3.64 muscle:2.90 esophagus:4.76 stomach:- intestine:6.39 colon:4.89     liver/hepato:6.00    lung:3.42 bladder:4.25 kidney:5.45 pituitary:3.74 thyroid/parathyroid:3.83 adrenal gland:- pancreas:2.86 breast:3.64 salivary:4.19
RNA-seq uterus:- placenta:- prostate:5.29 ovary:4.32 testis:3.85 heart:3.47 muscle:1.57 esophagus:- stomach:- intestine:- colon:4.82     liver/hepato:7.02        lung:4.25    bladder:- kidney:6.35 pituitary:- thyroid/parathyroid:3.90 adrenal gland:3.08 pancreas:- breast:4.88 salivary:-

Gene Information

IDs

Refseq ID NM_012212
Gene ID 22949
Unigene ID Hs.584864
Probe set ID -
Ensembl ID ENSG00000106853
GTEx ID ENSG00000106853

Orthologous Gene

Mouse[1]  NM_025968
Rat [0]  

Chromosomal Region

9q31.3  [114,312,002  -  114,362,135]

Gene Family (Interpro ID)

IPR002085  Alcohol dehydrogenase superfamily, zinc-containing
IPR014190  Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase

Link to Pubmed  (Pubmed ID)

8576264
12432938
12477932
14702039
15164053
15489334
17449869
19056867
19595472
19913121
20628086
20804502
21139048
21906983
22939629
23314186
23878198

Gene Ontology  (GO ID)

Biological Process

GO:0019369  arachidonic acid metabolic process
GO:0019371  cyclooxygenase pathway
GO:0006691  leukotriene metabolic process
GO:0009636  response to toxin

Cellular Component

GO:0005737  cytoplasm

Molecular Function

GO:0047522  15-oxoprostaglandin 13-oxidase activity
GO:0032440  2-alkenal reductase activity
GO:0004022  alcohol dehydrogenase (NAD) activity
GO:0008270  zinc ion binding