lysine (K)-specific demethylase 4B

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Synonym

jumonji domain containing 2B, Jumonji domain-containing protein 2B, KIAA0876, JHDM3B, JMJD2B, FLJ44906

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip cerebrum:5.62 cerebellum:5.97 brain stem:5.50 corpus callosum/glia:5.73 pineal gland:- peripheral nerve:5.61 spine:5.52 retina:- eye:- artery/aorta:6 vein:5.87 lymphnode:6.20 peripheral blood:- spleen:6.39 thymus:6.41 bone marrow:6.02 adipose:5.87 bone:- skin:6.28
CAGE cerebrum:3.91 cerebellum:- brain stem:3.60 corpus callosum/glia:4.07 pineal gland:4.35 peripheral nerve:- spine:3.85 retina:- eye:- artery/aorta:4.01 vein:3.81 lymphnode:3.88 peripheral blood:- spleen:3.67 thymus:3.69 bone marrow:- adipose:3.75 bone:- skin:-
RNA-seq cerebrum:1.83 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.58 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.51 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip uterus:6.01 placenta:6.27 prostate:6.68 ovary:6.08 testis:6.20 heart:5.75 muscle:5.62 esophagus:6.08 stomach:5.74 intestine:5.70 colon:5.74 liver/hepato:6.53 lung:5.70 bladder:- kidney:5.70 pituitary:6.22 thyroid/parathyroid:6.67 adrenal gland:6.12 pancreas:6.14 breast:6.27 salivary:5.67
CAGE uterus:4.18 placenta:4.39 prostate:4.00 ovary:3.74 testis:4.06 heart:3.69 muscle:4.30 esophagus:3.60 stomach:- intestine:3.34 colon:4.07     liver/hepato:3.74    lung:3.54 bladder:3.71 kidney:3.36 pituitary:3.86 thyroid/parathyroid:4.33 adrenal gland:- pancreas:3.93 breast:4.16 salivary:3.56
RNA-seq uterus:- placenta:- prostate:2.53 ovary:2.68 testis:3.03 heart:2.16 muscle:3.39 esophagus:- stomach:- intestine:- colon:2.07     liver/hepato:2.02        lung:1.86    bladder:- kidney:2.24 pituitary:- thyroid/parathyroid:3.89 adrenal gland:2.62 pancreas:- breast:2.13 salivary:-

Gene Information

IDs

Refseq ID NM_015015
Gene ID 23030
Unigene ID -
Probe set ID 212495_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000127663
GTEx ID ENSG00000127663

Orthologous Gene

Mouse[1]  NM_172132
Rat[1]  NM_172132

Chromosomal Region

19p13.3  [4,969,124  -  5,153,606]

Gene Family (Interpro ID)

IPR003347  Transcription factor jumonji/aspartyl beta-hydroxylase
IPR002999  Tudor domain
IPR001965  Zinc finger, PHD-type

Link to Pubmed  (Pubmed ID)

8619474
9110174
10048485
10737800
12168954
12477932
15057824
15138608
15302935
15489334
15927959
16169070
16344560
16603238
17611647
18713068
18984585
20379614
20682797
21445275
21502505
21906983
21930796
22133676
22505724
22745382
22770241
22939629
23046878
23376847
23455924
23589305
24024966
24077348
24473398
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0016568  chromatin modification
GO:0006355  regulation of transcription, DNA-dependent
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005634  nucleus

Molecular Function

GO:0016702  oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0008270  zinc ion binding