Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

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Synonym

KIAA0252, RTF1, GTL7

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:45 cerebellum:37.80 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:- spine:- retina:- eye:129.30 artery/aorta:- vein:66.60 lymphnode:40.40 peripheral blood:36.40 spleen:18.90 thymus:38.70 bone marrow:39.40 adipose:80.70 bone:51.20 skin:28.80
GeneChip cerebrum:6.98 cerebellum:7.33 brain stem:6.79 corpus callosum/glia:6.30 pineal gland:- peripheral nerve:6.77 spine:6.72 retina:- eye:- artery/aorta:6.72 vein:7.03 lymphnode:6.87 peripheral blood:- spleen:6.87 thymus:6.99 bone marrow:6.81 adipose:6.79 bone:- skin:7.21
CAGE cerebrum:4.38 cerebellum:- brain stem:3.99 corpus callosum/glia:3.89 pineal gland:4.47 peripheral nerve:- spine:3.95 retina:- eye:- artery/aorta:3.83 vein:4.15 lymphnode:3.70 peripheral blood:- spleen:4.32 thymus:4.23 bone marrow:- adipose:4.25 bone:- skin:-
RNA-seq cerebrum:4.20 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.98 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:4.24 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:54.70 placenta:29.10 prostate:112.60 ovary:37.30 testis:99.50 heart:38.30 muscle:160.70 esophagus:- stomach:63.70 intestine:32.40 colon:25.40     liver/hepato:73.90        lung:73.30    bladder:- kidney:135.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:26.70 breast:120.80 salivary:-
GeneChip uterus:7.30 placenta:7.70 prostate:7.38 ovary:7.36 testis:6.79 heart:6.72 muscle:7.67 esophagus:7.06 stomach:6.79 intestine:6.82 colon:6.49 liver/hepato:6.37 lung:6.68 bladder:- kidney:6.46 pituitary:6.19 thyroid/parathyroid:7.42 adrenal gland:6.90 pancreas:6.07 breast:7.47 salivary:6.61
CAGE uterus:4.42 placenta:4.69 prostate:4.30 ovary:4.30 testis:4.47 heart:4.17 muscle:4.95 esophagus:4.22 stomach:- intestine:4.19 colon:3.80     liver/hepato:3.97    lung:3.83 bladder:4.53 kidney:3.92 pituitary:4.23 thyroid/parathyroid:4.12 adrenal gland:- pancreas:3.61 breast:3.52 salivary:3.74
RNA-seq uterus:- placenta:- prostate:4.07 ovary:4.26 testis:4.49 heart:3.37 muscle:4.01 esophagus:- stomach:- intestine:- colon:3.74     liver/hepato:2.59        lung:3.37    bladder:- kidney:3.31 pituitary:- thyroid/parathyroid:4.37 adrenal gland:4.11 pancreas:- breast:3.67 salivary:-

Gene Information

IDs

Refseq ID NM_015138
Gene ID 23168
Unigene ID Hs.511096
Probe set ID 212301_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000137815
GTEx ID ENSG00000137815

Orthologous Gene

Mouse[1]  NM_030112
Rat[1]  NM_001108958

Chromosomal Region

15q15.1  [41,709,302  -  41,775,761]

Gene Family (Interpro ID)

IPR004343  Plus-3
IPR018144  Plus-3 domain, subgroup

Link to Pubmed  (Pubmed ID)

9039502
12168954
12477932
15489334
15632063
15923622
17081983
17353931
17576814
18029348
18184592
18469135
19345177
19471022
19953087
20178742
20305087
20379614
20467438
20881960
21139048
21406692
21693764
21726809
21832049
21906983
22082156
22405323
22863883
22939629
23463506
23602568
24101474
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0001711  endodermal cell fate commitment
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0051571  positive regulation of histone H3-K4 methylation
GO:0032968  positive regulation of RNA elongation from RNA polymerase II promoter
GO:0045944  positive regulation of transcription from RNA polymerase II promoter
GO:0019827  stem cell maintenance
GO:0006352  transcription initiation
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0016593  Cdc73/Paf1 complex
GO:0005730  nucleolus

Molecular Function

GO:0005515  protein binding
GO:0003697  single-stranded DNA binding