zinc finger protein 281

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Synonym

FLJ12859, ZNP-99, GZP1, zinc finger protein 281, ZBP-99, GC-box-binding zinc finger protein 1, Transcription factor ZBP-99, ZBP99, Zinc finger protein 281, Zinc finger DNA-binding protein 99, FLJ14378, ZNF281

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:62.80 cerebellum:75.60 brain stem:- corpus callosum/glia:233.30 pineal gland:- peripheral nerve:153.40 spine:- retina:- eye:29.40 artery/aorta:30 vein:- lymphnode:50.60 peripheral blood:18.20 spleen:18.90 thymus:90.20 bone marrow:- adipose:- bone:51.20 skin:24
GeneChip cerebrum:5.90 cerebellum:6.22 brain stem:5.68 corpus callosum/glia:6.56 pineal gland:- peripheral nerve:5.29 spine:5.61 retina:- eye:- artery/aorta:4.94 vein:4.72 lymphnode:5.81 peripheral blood:- spleen:6.16 thymus:6.92 bone marrow:6.03 adipose:5.25 bone:- skin:4.71
CAGE cerebrum:2.99 cerebellum:- brain stem:3.23 corpus callosum/glia:3.00 pineal gland:3.15 peripheral nerve:- spine:2.83 retina:- eye:- artery/aorta:2.05 vein:2.60 lymphnode:2.55 peripheral blood:- spleen:3.10 thymus:3.48 bone marrow:- adipose:2.67 bone:- skin:-
RNA-seq cerebrum:2.56 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.03 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:1.71 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:18.20 placenta:32.80 prostate:22.50 ovary:- testis:43.30 heart:38.30 muscle:20.10 esophagus:- stomach:- intestine:- colon:17     liver/hepato:10.60        lung:29.30    bladder:- kidney:62.40 pituitary:- thyroid/parathyroid:- adrenal gland:101.60 pancreas:26.70 breast:27.90 salivary:-
GeneChip uterus:5.66 placenta:5.70 prostate:5.51 ovary:5.76 testis:5.92 heart:5.11 muscle:5.17 esophagus:4.95 stomach:5.48 intestine:4.96 colon:4.20 liver/hepato:7.34 lung:5.34 bladder:- kidney:5.21 pituitary:5.07 thyroid/parathyroid:5.34 adrenal gland:5.37 pancreas:4.60 breast:5.35 salivary:5.25
CAGE uterus:2.65 placenta:2.99 prostate:2.68 ovary:2.61 testis:2.55 heart:2.21 muscle:2.23 esophagus:2.28 stomach:- intestine:2.41 colon:2.09     liver/hepato:2.98    lung:2.73 bladder:2.73 kidney:2.71 pituitary:2.77 thyroid/parathyroid:2.42 adrenal gland:- pancreas:1.98 breast:2.69 salivary:1.82
RNA-seq uterus:- placenta:- prostate:1.48 ovary:2.39 testis:2.65 heart:1.81 muscle:1.57 esophagus:- stomach:- intestine:- colon:1.70     liver/hepato:2.29        lung:1.98    bladder:- kidney:1.99 pituitary:- thyroid/parathyroid:2.06 adrenal gland:2.13 pancreas:- breast:1.92 salivary:-

Gene Information

IDs

Refseq ID NM_012482
Gene ID 23528
Unigene ID Hs.59757
Probe set ID 218401_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000162702
GTEx ID ENSG00000162702

Orthologous Gene

Mouse[8]  NM_001160251, NM_177643
Rat[1]  NM_001012030, NM_177643

Chromosomal Region

1q32.1  [200,375,827  -  200,379,184]

Gene Family (Interpro ID)

IPR015880  Zinc finger, C2H2-like
IPR007087  Zinc finger, C2H2-type

Link to Pubmed  (Pubmed ID)

10405178
10448078
12477932
12771217
14702039
15342556
15489334
16009940
16344560
17314511
17761849
18029348
18757296
18781797
19147588
19322201
19471022
20306291
20811636
21139048
21693764
21906983
21963094
21987572
21988832
22678362
22939629
23287719
23602568
24185900
24250222
24654937
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0010172  embryonic body morphogenesis
GO:0010629  negative regulation of gene expression
GO:0045892  negative regulation of transcription, DNA-dependent
GO:0045893  positive regulation of transcription, DNA-dependent
GO:0048863  stem cell differentiation
GO:0006351  transcription, DNA-dependent

Cellular Component

GO:0005730  nucleolus
GO:0005634  nucleus

Molecular Function

GO:0044212  DNA regulatory region binding
GO:0046872  metal ion binding
GO:0005515  protein binding
GO:0043565  sequence-specific DNA binding
GO:0003714  transcription corepressor activity
GO:0003700  transcription factor activity