ventral anterior homeobox 2

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Synonym

DRES93, ventral anterior homeobox 2, Ventral anterior homeobox 2, VAX2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:2.40 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:47 artery/aorta:- vein:- lymphnode:10.10 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:4.30 cerebellum:5.18 brain stem:4.24 corpus callosum/glia:4.25 pineal gland:- peripheral nerve:4.16 spine:4.26 retina:- eye:- artery/aorta:4.35 vein:4.53 lymphnode:4.42 peripheral blood:- spleen:4.08 thymus:4.20 bone marrow:4.32 adipose:4.40 bone:- skin:4.48
CAGE cerebrum:1.00 cerebellum:- brain stem:0.62 corpus callosum/glia:0.82 pineal gland:1.73 peripheral nerve:- spine:0.56 retina:- eye:- artery/aorta:0.34 vein:1.10 lymphnode:0.35 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:1.07 bone:- skin:-
RNA-seq cerebrum:0.25 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.42 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.37 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:4.90    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:4.13 placenta:4.20 prostate:4.06 ovary:4.17 testis:4.06 heart:4.19 muscle:4.38 esophagus:4.39 stomach:4.06 intestine:4.33 colon:4.25 liver/hepato:4.17 lung:4.15 bladder:- kidney:4.16 pituitary:4.31 thyroid/parathyroid:4.08 adrenal gland:4.34 pancreas:4.40 breast:4.19 salivary:4.20
CAGE uterus:1.32 placenta:0.68 prostate:1.23 ovary:1.20 testis:0.31 heart:1.06 muscle:0.89 esophagus:1.04 stomach:- intestine:0.21 colon:0.59     liver/hepato:0.14    lung:0.69 bladder:0.58 kidney:0.39 pituitary:1.11 thyroid/parathyroid:0.57 adrenal gland:- pancreas:1.87 breast:1.16 salivary:1.00
RNA-seq uterus:- placenta:- prostate:0.35 ovary:0.16 testis:0.03 heart:0.01 muscle:0 esophagus:- stomach:- intestine:- colon:0.50     liver/hepato:0.01        lung:0.28    bladder:- kidney:0.07 pituitary:- thyroid/parathyroid:0.23 adrenal gland:0.14 pancreas:- breast:0.75 salivary:-

Gene Information

IDs

Refseq ID NM_012476
Gene ID 25806
Unigene ID Hs.249170
Probe set ID 220443_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000116035
GTEx ID ENSG00000116035

Orthologous Gene

Mouse[1]  NM_011912
Rat [0]  

Chromosomal Region

2p13.3  [71,127,720  -  71,160,576]

Gene Family (Interpro ID)

IPR001356  Homeobox
IPR009057  Homeodomain-like
IPR012287  Homeodomain-related

Link to Pubmed  (Pubmed ID)

10485894
12477932
15489334
16953426
17963489
19913121
20628086
21697133
23322567

Gene Ontology  (GO ID)

Biological Process

GO:0007409  axonogenesis
GO:0009950  dorsal/ventral axis specification
GO:0007398  ectoderm development
GO:0048048  embryonic eye morphogenesis
GO:0030900  forebrain development
GO:0000122  negative regulation of transcription from RNA polymerase II promoter
GO:0060041  retina development in camera-type eye
GO:0006351  transcription, DNA-dependent
GO:0007601  visual perception
GO:0016055  Wnt receptor signaling pathway

Cellular Component

GO:0005737  cytoplasm
GO:0005634  nucleus

Molecular Function

GO:0031490  chromatin DNA binding
GO:0003700  transcription factor activity