peroxiredoxin 5

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Synonym

PRDX6, peroxiredoxin 5, Alu corepressor 1, AOEB166, PRDX5, Liver tissue 2D-page spot 71B, Thioredoxin peroxidase PMP20, MGC142285, Thioredoxin reductase, SBBI10, Antioxidant enzyme B166, Peroxiredoxin-5, mitochondrial precursor, ACR1, MGC142283, TPx type VI, B166, MGC117264, PRXV, Peroxisomal antioxidant enzyme, PMP20, Prx-V

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST nodata
GeneChip nodata
CAGE cerebrum:4.97 cerebellum:- brain stem:4.83 corpus callosum/glia:4.54 pineal gland:4.88 peripheral nerve:- spine:4.79 retina:- eye:- artery/aorta:4.75 vein:4.44 lymphnode:4.41 peripheral blood:- spleen:4.19 thymus:4.11 bone marrow:- adipose:4.10 bone:- skin:-
RNA-seq cerebrum:6.82 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.42 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:6.53 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST nodata
GeneChip nodata
CAGE uterus:4.44 placenta:4.87 prostate:4.40 ovary:4.70 testis:4.57 heart:5.33 muscle:5.15 esophagus:4.98 stomach:- intestine:4.68 colon:5.30     liver/hepato:4.78    lung:5.02 bladder:4.34 kidney:5.05 pituitary:4.64 thyroid/parathyroid:5.39 adrenal gland:- pancreas:5.24 breast:4.49 salivary:5.53
RNA-seq uterus:- placenta:- prostate:6.99 ovary:7.29 testis:7.08 heart:6.43 muscle:5.60 esophagus:- stomach:- intestine:- colon:7.20     liver/hepato:6.48        lung:7.47    bladder:- kidney:7.55 pituitary:- thyroid/parathyroid:7.79 adrenal gland:6.46 pancreas:- breast:6.68 salivary:-

Gene Information

IDs

Refseq ID NM_012094
Gene ID 25824
Unigene ID -
Probe set ID -
Ensembl ID ENSG00000126432
GTEx ID ENSG00000126432

Orthologous Gene

Mouse[1]  NM_012021
Rat[1]  NM_053610

Chromosomal Region

11q13.1  [64,085,560  -  64,089,283]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

1286669
10095767
10424490
10514471
10521424
10679306
10751410
10931946
11518528
11832487
12417342
12477932
12517450
14662316
14732291
14741336
15046979
15276323
15280035
15304327
15489334
15785239
15848167
16169070
16781710
16817890
17601350
17623739
17628720
17892856
18219526
18262354
18378575
18489898
18977241
19016754
19056867
19336475
19615732
20178365
20186120
20305821
20596022
20877624
20937353
21102463
21139048
21832049
21890473
21906983
22020876
22304920
22837380
22939629
23000965
23216451
24250222
24385276
24550385
24583282
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0034614  cellular response to reactive oxygen species
GO:0042744  hydrogen peroxide catabolic process
GO:0006954  inflammatory response
GO:0070995  NADPH oxidation
GO:0043066  negative regulation of apoptosis
GO:0043154  negative regulation of caspase activity
GO:0051354  negative regulation of oxidoreductase activity
GO:0016480  negative regulation of transcription from RNA polymerase III promoter
GO:0032967  positive regulation of collagen biosynthetic process
GO:0060785  regulation of apoptosis involved in tissue homeostasis
GO:0006979  response to oxidative stress

Cellular Component

GO:0005737  cytoplasm
GO:0031410  cytoplasmic vesicle
GO:0005829  cytosol
GO:0043231  intracellular membrane-bounded organelle
GO:0005739  mitochondrion
GO:0005634  nucleus
GO:0048471  perinuclear region of cytoplasm
GO:0005782  peroxisomal matrix
GO:0005777  peroxisome

Molecular Function

GO:0016209  antioxidant activity
GO:0043027  caspase inhibitor activity
GO:0004601  peroxidase activity
GO:0051920  peroxiredoxin activity
GO:0046983  protein dimerization activity
GO:0005102  receptor binding