GTPase activating protein and VPS9 domains 1

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Synonym

RAP6, MGC138848, MGC138847, GAPVD1, DKFZP434C212, GTPase activating protein and VPS9 domains 1, KIAA1521

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:35.60 cerebellum:12.60 brain stem:- corpus callosum/glia:58.30 pineal gland:- peripheral nerve:122.70 spine:- retina:- eye:47 artery/aorta:60 vein:- lymphnode:50.60 peripheral blood:72.90 spleen:37.80 thymus:25.80 bone marrow:- adipose:- bone:25.60 skin:76.80
GeneChip cerebrum:5.09 cerebellum:4.84 brain stem:5.22 corpus callosum/glia:5.14 pineal gland:- peripheral nerve:5.33 spine:5.11 retina:- eye:- artery/aorta:5.01 vein:4.91 lymphnode:5.16 peripheral blood:- spleen:5.36 thymus:6.02 bone marrow:5.97 adipose:5.04 bone:- skin:5.38
CAGE cerebrum:3.68 cerebellum:- brain stem:3.75 corpus callosum/glia:3.76 pineal gland:3.86 peripheral nerve:- spine:3.66 retina:- eye:- artery/aorta:3.63 vein:3.42 lymphnode:3.52 peripheral blood:- spleen:3.42 thymus:3.46 bone marrow:- adipose:3.51 bone:- skin:-
RNA-seq cerebrum:3.28 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.99 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.41 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:45.60 placenta:61.90 prostate:135.20 ovary:37.30 testis:77.90 heart:- muscle:40.20 esophagus:- stomach:42.50 intestine:- colon:17     liver/hepato:73.90        lung:34.20    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:327.50 adrenal gland:50.80 pancreas:- breast:55.80 salivary:-
GeneChip uterus:5.27 placenta:5.96 prostate:5.35 ovary:5.18 testis:6.89 heart:5.19 muscle:4.98 esophagus:5.58 stomach:5.01 intestine:4.91 colon:4.81 liver/hepato:5.13 lung:5.29 bladder:- kidney:5.43 pituitary:5.21 thyroid/parathyroid:5.44 adrenal gland:5.13 pancreas:4.67 breast:5.11 salivary:4.94
CAGE uterus:3.56 placenta:3.72 prostate:3.38 ovary:3.26 testis:3.84 heart:3.52 muscle:3.57 esophagus:3.41 stomach:- intestine:3.33 colon:3.22     liver/hepato:3.12    lung:3.74 bladder:3.43 kidney:3.15 pituitary:3.78 thyroid/parathyroid:3.54 adrenal gland:- pancreas:2.94 breast:3.58 salivary:3.09
RNA-seq uterus:- placenta:- prostate:3.06 ovary:3.21 testis:3.93 heart:2.74 muscle:3.60 esophagus:- stomach:- intestine:- colon:2.82     liver/hepato:2.20        lung:3.32    bladder:- kidney:2.93 pituitary:- thyroid/parathyroid:3.57 adrenal gland:3.09 pancreas:- breast:3.36 salivary:-

Gene Information

IDs

Refseq ID NM_015635
Gene ID 26130
Unigene ID Hs.495134
Probe set ID 212804_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000165219
GTEx ID ENSG00000165219

Orthologous Gene

Mouse[2]  NM_025709
Rat[2]  NM_025709

Chromosomal Region

9q33.3  [128,024,073  -  128,129,486]

Gene Family (Interpro ID)

IPR001936  Ras GTPase-activating protein
IPR008936  Rho GTPase activation protein
IPR003123  Vacuolar sorting protein 9
IPR013995  Vacuolar sorting protein 9, subgroup

Link to Pubmed  (Pubmed ID)

7566098
8889548
10819331
12477932
14702039
15302935
15324660
16410077
17545148
18187620
18654987
19322201
20360068
21139048
21890473
21906983
22145905
22586326
22863883
22939629
24250222
24255178
24816145

Gene Ontology  (GO ID)

Biological Process

GO:0006897  endocytosis
GO:0051223  regulation of protein transport
GO:0051056  regulation of small GTPase mediated signal transduction
GO:0007165  signal transduction

Cellular Component

GO:0005829  cytosol
GO:0005768  endosome
GO:0016020  membrane

Molecular Function

GO:0032794  GTPase activating protein binding
GO:0005096  GTPase activator activity
GO:0005085  guanyl-nucleotide exchange factor activity