NADPH oxidase 1

Synonym

NOX1, NADPH oxidase homolog 1, NADH/NADPH mitogenic oxidase subunit P65-MOX, NOH1, NOX-1, GP91-2, NOH-1, Mitogenic oxidase 1, NADPH oxidase 1

normal 40 tissues
cell lines, primary cells, adult tissues and fetal tissues (FANTOM5 CAGE)

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain

blood

connective

EST

cerebrum:-

cerebellum:25.20

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:-

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:-

bone:-

skin:4.80

GeneChip

cerebrum:2.67

cerebellum:2.57

brain stem:2.70

corpus callosum/glia:2.56

pineal gland:-

peripheral nerve:2.56

spine:2.56

retina:-

eye:-

artery/aorta:2.64

vein:2.59

lymphnode:2.65

peripheral blood:-

spleen:2.57

thymus:2.57

bone marrow:2.73

adipose:2.65

bone:-

skin:2.76

CAGE

cerebrum:0

cerebellum:-

brain stem:0

corpus callosum/glia:0

pineal gland:0

peripheral nerve:-

spine:0

retina:-

eye:-

artery/aorta:0

vein:0

lymphnode:0.03

peripheral blood:-

spleen:0

thymus:0.23

bone marrow:-

adipose:0

bone:-

skin:-

RNA-seq

cerebrum:0.00

cerebellum:-

brain stem:-

corpus callosum/glia:-

pineal gland:-

peripheral nerve:-

spine:-

retina:-

eye:-

artery/aorta:-

vein:-

lymphnode:0.00

peripheral blood:-

spleen:-

thymus:-

bone marrow:-

adipose:0

bone:-

skin:-

reproductive

muscular

alimentary

liver

lung

urinary

endo/exo-crine

EST

uterus:-

placenta:-

prostate:-

ovary:-

testis:-

heart:-

muscle:-

esophagus:-

stomach:-

intestine:32.40

colon:525.70

liver/hepato:-

lung:-

bladder:-

kidney:-

pituitary:-

thyroid/parathyroid:-

adrenal gland:-

pancreas:-

breast:9.30

salivary:-

GeneChip

uterus:2.60

placenta:2.55

prostate:2.66

ovary:2.55

testis:2.58

heart:2.55

muscle:2.77

esophagus:2.57

stomach:2.56

intestine:2.81

colon:5.62

liver/hepato:2.56

lung:2.59

bladder:-

kidney:2.60

pituitary:2.66

thyroid/parathyroid:2.65

adrenal gland:2.64

pancreas:2.86

breast:2.60

salivary:2.76

CAGE

uterus:0

placenta:0

prostate:0

ovary:0

testis:0.12

heart:0

muscle:0

esophagus:0

stomach:-

intestine:0.07

colon:3.21

liver/hepato:0

lung:0

bladder:0.26

kidney:0

pituitary:0

thyroid/parathyroid:0

adrenal gland:-

pancreas:0

breast:0

salivary:0

RNA-seq

uterus:-

placenta:-

prostate:0.00

ovary:0.16

testis:0.19

heart:0

muscle:0

esophagus:-

stomach:-

intestine:-

colon:1.28

liver/hepato:0.00

lung:0.00

bladder:-

kidney:0.00

pituitary:-

thyroid/parathyroid:0

adrenal gland:0.04

pancreas:-

breast:0.00

salivary:-

IDs

Refseq ID	NM_007052
Gene ID	27035
Unigene ID	Hs.592227
Probe set ID	206418_at [HG-U133_Plus_2]
Ensembl ID	ENSG00000007952
GTEx ID	ENSG00000007952

Orthologous Gene

Mouse[1]	NM_172203
Rat[1]	NM_172203

Chromosomal Region

Xq22.1 [100,098,313 - 100,129,334]

Search genes near this gene
- Between -5kb and +5kb
- Between -10kb and +10kb

Gene Family (Interpro ID)

Gene Ontology (GO ID)

Biological Process

GO:0001525	angiogenesis
GO:0016477	cell migration
GO:0022900	electron transport chain
GO:0030198	extracellular matrix organization
GO:0006746	FADH2 metabolic process
GO:0042743	hydrogen peroxide metabolic process
GO:0006954	inflammatory response
GO:0051454	intracellular pH elevation
GO:0006739	NADP metabolic process
GO:0055114	oxidation reduction
GO:0008284	positive regulation of cell proliferation
GO:0045726	positive regulation of integrin biosynthetic process
GO:0048661	positive regulation of smooth muscle cell proliferation
GO:0010575	positive regulation vascular endothelial growth factor production
GO:0015992	proton transport
GO:0008217	regulation of blood pressure
GO:0003081	regulation of systemic arterial blood pressure by renin-angiotensin
GO:0045730	respiratory burst
GO:0009268	response to pH
GO:0006950	response to stress
GO:0007165	signal transduction
GO:0042554	superoxide anion generation
GO:0006801	superoxide metabolic process

Cellular Component

GO:0030054	cell junction
GO:0005769	early endosome
GO:0016021	integral to membrane
GO:0071438	invadopodium membrane
GO:0043020	NADPH oxidase complex

Molecular Function

GO:0046872	metal ion binding
GO:0050661	NADP or NADPH binding
GO:0005515	protein binding
GO:0048365	Rac GTPase binding
GO:0016175	superoxide-generating NADPH oxidase activity
GO:0030171	voltage-gated proton channel activity

NADPH oxidase 1

Synonym

Expression Pattern

Choropleth map on BodyParts3D

Classification in 40 Organs

Gene Information

IDs

Orthologous Gene

Chromosomal Region

Gene Family (Interpro ID)

Link to Pubmed (Pubmed ID)

Gene Ontology (GO ID)

Biological Process

Cellular Component

Molecular Function