glutamate receptor, ionotropic, kainate 4

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Synonym

GRIK, glutamate receptor, ionotropic, kainate 4, KA1, EAA1, Glutamate receptor, ionotropic kainate 4 precursor, Glutamate receptor KA-1, GRIK4, Excitatory amino acid receptor 1

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:26.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:30.70 spine:- retina:237.30 eye:- artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:- bone:12.80 skin:24
GeneChip cerebrum:4.50 cerebellum:4.26 brain stem:4.46 corpus callosum/glia:4.44 pineal gland:- peripheral nerve:3.96 spine:4.49 retina:- eye:- artery/aorta:4 vein:4.16 lymphnode:3.91 peripheral blood:- spleen:3.77 thymus:3.88 bone marrow:3.84 adipose:4.10 bone:- skin:4.23
CAGE cerebrum:2.86 cerebellum:- brain stem:3.17 corpus callosum/glia:3.06 pineal gland:1.37 peripheral nerve:- spine:2.92 retina:- eye:- artery/aorta:0.47 vein:0.18 lymphnode:0.03 peripheral blood:- spleen:0.45 thymus:0.06 bone marrow:- adipose:0.14 bone:- skin:-
RNA-seq cerebrum:1.54 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.04 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.01 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:3.60 prostate:45.10 ovary:- testis:38.90 heart:- muscle:- esophagus:- stomach:- intestine:- colon:8.50     liver/hepato:21.10        lung:9.80    bladder:- kidney:- pituitary:- thyroid/parathyroid:- adrenal gland:50.80 pancreas:8.90 breast:- salivary:-
GeneChip uterus:3.84 placenta:3.78 prostate:3.64 ovary:4.13 testis:3.99 heart:3.93 muscle:4.22 esophagus:4.06 stomach:3.94 intestine:4 colon:4.06 liver/hepato:4 lung:3.97 bladder:- kidney:3.84 pituitary:4.01 thyroid/parathyroid:4.13 adrenal gland:4.10 pancreas:4.34 breast:3.86 salivary:3.96
CAGE uterus:0.32 placenta:0.37 prostate:0.58 ovary:2.11 testis:0.76 heart:0.63 muscle:0.09 esophagus:0.52 stomach:- intestine:0.21 colon:0.39     liver/hepato:0    lung:1.55 bladder:0.18 kidney:0.15 pituitary:1.65 thyroid/parathyroid:0.57 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.05 ovary:1.15 testis:0.40 heart:0.03 muscle:0.02 esophagus:- stomach:- intestine:- colon:0.02     liver/hepato:0.01        lung:0.90    bladder:- kidney:0.03 pituitary:- thyroid/parathyroid:0.69 adrenal gland:0.03 pancreas:- breast:0.01 salivary:-

Gene Information

IDs

Refseq ID NM_014619
Gene ID 2900
Unigene ID Hs.568901
Probe set ID 208552_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000149403
GTEx ID ENSG00000149403

Orthologous Gene

Mouse[1]  NM_175481
Rat [0]  

Chromosomal Region

11q23.3  [120,382,468  -  120,859,101]

Gene Family (Interpro ID)

IPR001320  Ionotropic glutamate receptor
IPR001508  NMDA receptor

Link to Pubmed  (Pubmed ID)

7527545
8263508
8288598
11334999
12477932
12954862
14617813
15782196
16325263
16344560
16819533
18289755
18824690
19086053
19125103
19328558
19342380
19384319
19924111
20110084
20125193
20201926
20379614
20859245
21215464
22052594
23728934

Gene Ontology  (GO ID)

Biological Process

GO:0007215  glutamate signaling pathway
GO:0007268  synaptic transmission
GO:0006810  transport

Cellular Component

GO:0030054  cell junction
GO:0005887  integral to plasma membrane
GO:0032983  kainate selective glutamate receptor complex
GO:0005886  plasma membrane
GO:0045211  postsynaptic membrane
GO:0042734  presynaptic membrane

Molecular Function

GO:0005234  extracellular-glutamate-gated ion channel activity
GO:0015277  kainate selective glutamate receptor activity