protein kinase C and casein kinase substrate in neurons 3

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Synonym

SH3 domain-containing protein 6511, Endophilin I, SDPIII, PACSIN3

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:19 cerebellum:- brain stem:- corpus callosum/glia:29.20 pineal gland:- peripheral nerve:- spine:- retina:- eye:41.10 artery/aorta:- vein:- lymphnode:- peripheral blood:- spleen:- thymus:- bone marrow:- adipose:80.70 bone:- skin:4.80
GeneChip cerebrum:5.33 cerebellum:5.32 brain stem:5.30 corpus callosum/glia:6.15 pineal gland:- peripheral nerve:5.63 spine:5.88 retina:- eye:- artery/aorta:5.87 vein:6.05 lymphnode:5.22 peripheral blood:- spleen:4.72 thymus:4.44 bone marrow:4.72 adipose:5.30 bone:- skin:5.66
CAGE cerebrum:1.95 cerebellum:- brain stem:2.45 corpus callosum/glia:2.86 pineal gland:1.20 peripheral nerve:- spine:2.26 retina:- eye:- artery/aorta:2.83 vein:1.80 lymphnode:1.65 peripheral blood:- spleen:0.92 thymus:0.33 bone marrow:- adipose:2.20 bone:- skin:-
RNA-seq cerebrum:0.01 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.90 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:2.43 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:72.90 prostate:22.50 ovary:74.50 testis:- heart:25.50 muscle:321.40 esophagus:- stomach:- intestine:- colon:42.40     liver/hepato:21.10        lung:34.20    bladder:- kidney:20.80 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:17.80 breast:27.90 salivary:-
GeneChip uterus:5.67 placenta:6.33 prostate:5.67 ovary:5.43 testis:4.37 heart:6.44 muscle:8.02 esophagus:7.20 stomach:5.62 intestine:5.76 colon:5.28 liver/hepato:6.36 lung:5.43 bladder:- kidney:5.46 pituitary:4.81 thyroid/parathyroid:6.18 adrenal gland:6.44 pancreas:5.84 breast:5.86 salivary:6.12
CAGE uterus:2.45 placenta:2.71 prostate:2.66 ovary:2.43 testis:1.12 heart:3.54 muscle:4.89 esophagus:2.90 stomach:- intestine:1.17 colon:2.34     liver/hepato:2.79    lung:1.91 bladder:2.52 kidney:1.76 pituitary:0.26 thyroid/parathyroid:2.82 adrenal gland:- pancreas:3.23 breast:2.19 salivary:2.26
RNA-seq uterus:- placenta:- prostate:4.01 ovary:3.35 testis:1.55 heart:4.58 muscle:6.85 esophagus:- stomach:- intestine:- colon:1.77     liver/hepato:3.42        lung:1.60    bladder:- kidney:0.49 pituitary:- thyroid/parathyroid:2.41 adrenal gland:1.30 pancreas:- breast:0.13 salivary:-

Gene Information

IDs

Refseq ID NM_016223
Gene ID 29763
Unigene ID Hs.334639
Probe set ID 218744_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000165912
GTEx ID ENSG00000165912

Orthologous Gene

Mouse[2]  NM_028733, NM_030880
Rat[1]  NM_001009966, NM_030880

Chromosomal Region

11p11.2  [47,199,076  -  47,207,994]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

10531379
11082044
11179684
12477932
12952982
14679214
14702039
15226389
15280379
15489334
15719014
16374509
16627472
17081983
17353931
18174177
18316326
19041431
19056867
19294699
20360068
21044950
21139048
21987572
22558309
22573331
22939629
23000965
23398456
24500282

Gene Ontology  (GO ID)

Biological Process

GO:0006897  endocytosis
GO:0051926  negative regulation of calcium ion transport
GO:0045806  negative regulation of endocytosis
GO:0051044  positive regulation of membrane protein ectodomain proteolysis

Cellular Component

GO:0005737  cytoplasm
GO:0005886  plasma membrane

Molecular Function

GO:0019855  calcium channel inhibitor activity
GO:0008092  cytoskeletal protein binding
GO:0008289  lipid binding
GO:0005515  protein binding