granzyme K (granzyme 3; tryptase II)

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Synonym

GZMK, Granzyme K precursor, granzyme K (granzyme 3; tryptase II), Granzyme-3, NK-TRYP-2, PRSS, Fragmentin-3, NK-tryptase-2, TRYP2

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:- cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:118.60 eye:- artery/aorta:- vein:- lymphnode:20.20 peripheral blood:18.20 spleen:- thymus:12.90 bone marrow:- adipose:- bone:- skin:19.20
GeneChip cerebrum:5.41 cerebellum:5.19 brain stem:5.52 corpus callosum/glia:5.36 pineal gland:- peripheral nerve:5.62 spine:5.36 retina:- eye:- artery/aorta:5.64 vein:5.70 lymphnode:7.33 peripheral blood:- spleen:8.13 thymus:7.03 bone marrow:6.82 adipose:6.17 bone:- skin:5.70
CAGE cerebrum:0.13 cerebellum:- brain stem:0.46 corpus callosum/glia:0.29 pineal gland:0.62 peripheral nerve:- spine:0.74 retina:- eye:- artery/aorta:1.57 vein:3.07 lymphnode:3.03 peripheral blood:- spleen:3.67 thymus:1.43 bone marrow:- adipose:1.51 bone:- skin:-
RNA-seq cerebrum:0.10 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:6.27 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.44 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:- placenta:- prostate:- ovary:- testis:- heart:- muscle:- esophagus:- stomach:- intestine:- colon:-     liver/hepato:-        lung:-    bladder:- kidney:- pituitary:- thyroid/parathyroid:163.70 adrenal gland:- pancreas:- breast:- salivary:-
GeneChip uterus:5.89 placenta:5.18 prostate:5.33 ovary:5.61 testis:5.05 heart:5.80 muscle:5.74 esophagus:5.58 stomach:6.24 intestine:5.87 colon:5.90 liver/hepato:6.38 lung:6.49 bladder:- kidney:5.44 pituitary:5.54 thyroid/parathyroid:5.65 adrenal gland:5.65 pancreas:5.97 breast:5.44 salivary:5.87
CAGE uterus:1.69 placenta:0.68 prostate:2.18 ovary:1.25 testis:1.08 heart:0.46 muscle:0.35 esophagus:1.41 stomach:- intestine:1.56 colon:0.83     liver/hepato:1.51    lung:2.54 bladder:1.86 kidney:1.76 pituitary:0.42 thyroid/parathyroid:1.46 adrenal gland:- pancreas:0.94 breast:1.53 salivary:2.12
RNA-seq uterus:- placenta:- prostate:1.18 ovary:1.08 testis:1.34 heart:0.72 muscle:0.32 esophagus:- stomach:- intestine:- colon:0.30     liver/hepato:1.29        lung:3.97    bladder:- kidney:0.81 pituitary:- thyroid/parathyroid:0.37 adrenal gland:4.54 pancreas:- breast:0.60 salivary:-

Gene Information

IDs

Refseq ID NM_002104
Gene ID 3003
Unigene ID Hs.277937
Probe set ID 206666_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000113088
GTEx ID ENSG00000113088

Orthologous Gene

Mouse[1]  NM_008196
Rat [0]  

Chromosomal Region

5q11.2  [54,320,081  -  54,330,398]

Gene Family (Interpro ID)

IPR001254  Peptidase S1/S6, chymotrypsin/Hap
IPR001314  Peptidase S1A, chymotrypsin
IPR009003  Serine/cysteine peptidase, trypsin-like

Link to Pubmed  (Pubmed ID)

1460416
3262682
7758581
8039831
8656064
8929545
12384499
12387726
12477932
15489334
17008916
17308307
17438453
19059912
19201868
20377743
20876349
21666061
21988832
24711407

Gene Ontology  (GO ID)

Biological Process

GO:0006508  proteolysis

Cellular Component

GO:0005576  extracellular region

Molecular Function

GO:0004252  serine-type endopeptidase activity
GO:0008236  serine-type peptidase activity