5', 3'-nucleotidase, cytosolic

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Synonym

PN-II, DNT, 5', 3'-nucleotidase, cytosolic, NT5C, DNT-1, DNT1, PN-I, cdN, UMPH2, P5N2, deoxy (pyrimidine), 5'(3')-deoxyribonucleotidase, cytosolic type, Deoxy-5'-nucleotidase 1, dNT-1, Cytosolic 5',3'-pyrimidine nucleotidase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:16.60 cerebellum:12.60 brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:41.10 artery/aorta:- vein:- lymphnode:30.30 peripheral blood:54.70 spleen:- thymus:12.90 bone marrow:- adipose:- bone:- skin:9.60
GeneChip cerebrum:6.05 cerebellum:6.27 brain stem:6.20 corpus callosum/glia:6.16 pineal gland:- peripheral nerve:5.69 spine:5.83 retina:- eye:- artery/aorta:5.97 vein:6.07 lymphnode:6.33 peripheral blood:- spleen:6.03 thymus:6.26 bone marrow:5.93 adipose:6.01 bone:- skin:6.16
CAGE cerebrum:2.37 cerebellum:- brain stem:2.53 corpus callosum/glia:3.00 pineal gland:1.78 peripheral nerve:- spine:2.49 retina:- eye:- artery/aorta:3.13 vein:3.61 lymphnode:3.41 peripheral blood:- spleen:3.09 thymus:2.82 bone marrow:- adipose:2.34 bone:- skin:-
RNA-seq cerebrum:2.61 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:2.57 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:3.74 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:9.10 placenta:3.60 prostate:90.10 ovary:111.80 testis:13 heart:25.50 muscle:20.10 esophagus:- stomach:- intestine:64.80 colon:-     liver/hepato:-        lung:14.70    bladder:- kidney:31.20 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:35.60 breast:- salivary:-
GeneChip uterus:6.15 placenta:5.55 prostate:6.12 ovary:6.37 testis:5.85 heart:6.15 muscle:6.29 esophagus:6.31 stomach:6.09 intestine:6.44 colon:6.37 liver/hepato:6.08 lung:6.01 bladder:- kidney:6.32 pituitary:5.80 thyroid/parathyroid:6.19 adrenal gland:6.09 pancreas:6.34 breast:6.10 salivary:6.15
CAGE uterus:3.01 placenta:2.51 prostate:3.02 ovary:3.00 testis:2.67 heart:2.98 muscle:3.25 esophagus:3.13 stomach:- intestine:3.49 colon:3.58     liver/hepato:2.41    lung:3.18 bladder:3.09 kidney:3.09 pituitary:1.90 thyroid/parathyroid:3.11 adrenal gland:- pancreas:3.26 breast:2.69 salivary:2.72
RNA-seq uterus:- placenta:- prostate:3.94 ovary:3.53 testis:3.06 heart:1.96 muscle:3.44 esophagus:- stomach:- intestine:- colon:3.05     liver/hepato:2.58        lung:3.12    bladder:- kidney:3.64 pituitary:- thyroid/parathyroid:4.21 adrenal gland:4.19 pancreas:- breast:3.40 salivary:-

Gene Information

IDs

Refseq ID NM_014595
Gene ID 30833
Unigene ID Hs.67201
Probe set ID 219214_s_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000125458
GTEx ID ENSG00000125458

Orthologous Gene

Mouse[1]  NM_015807
Rat[1]  NM_015807

Chromosomal Region

17q25.1  [73,126,324  -  73,127,877]

Gene Family (Interpro ID)

-

Link to Pubmed  (Pubmed ID)

2157703
2833155
3186746
10681516
10899995
12234672
12418222
12477932
12714505
14702039
15136231
15489334
17207965
18029348
19056867
20877624
21906983
24250222

Gene Ontology  (GO ID)

Biological Process

GO:0016311  dephosphorylation
GO:0055086  nucleobase, nucleoside and nucleotide metabolic process
GO:0006144  purine base metabolic process
GO:0006195  purine nucleotide catabolic process
GO:0006206  pyrimidine base metabolic process
GO:0009223  pyrimidine deoxyribonucleotide catabolic process
GO:0046135  pyrimidine nucleoside catabolic process

Cellular Component

GO:0005737  cytoplasm
GO:0005829  cytosol
GO:0005739  mitochondrion
GO:0005634  nucleus

Molecular Function

GO:0008253  5'-nucleotidase activity
GO:0046872  metal ion binding
GO:0008252  nucleotidase activity
GO:0019103  pyrimidine nucleotide binding