hydroxysteroid (17-beta) dehydrogenase 3

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Synonym

HSD17B3, Estradiol 17-beta-dehydrogenase 3, EDH17B3, 17-beta-HSD 3, hydroxysteroid (17-beta) dehydrogenase 3, Testicular 17-beta-hydroxysteroid dehydrogenase

Expression Pattern

Choropleth map on BodyParts3D

Choropleth maps on 3D human body images were generated by the relative gene expression values measured by GeneChip.

Classification in 40 Organs

brain blood connective
EST cerebrum:87.70 cerebellum:226.70 brain stem:- corpus callosum/glia:87.50 pineal gland:- peripheral nerve:92 spine:- retina:- eye:35.30 artery/aorta:30 vein:333.20 lymphnode:80.90 peripheral blood:54.70 spleen:56.70 thymus:64.40 bone marrow:39.40 adipose:- bone:51.20 skin:28.80
GeneChip cerebrum:5.55 cerebellum:5.04 brain stem:5.60 corpus callosum/glia:6.37 pineal gland:- peripheral nerve:5.49 spine:5.68 retina:- eye:- artery/aorta:5.35 vein:5.17 lymphnode:4.95 peripheral blood:- spleen:4.72 thymus:5.05 bone marrow:5.25 adipose:5.19 bone:- skin:5.31
CAGE cerebrum:0.01 cerebellum:- brain stem:0 corpus callosum/glia:0 pineal gland:0 peripheral nerve:- spine:0 retina:- eye:- artery/aorta:0 vein:0 lymphnode:0 peripheral blood:- spleen:0 thymus:0 bone marrow:- adipose:0 bone:- skin:-
RNA-seq cerebrum:0.82 cerebellum:- brain stem:- corpus callosum/glia:- pineal gland:- peripheral nerve:- spine:- retina:- eye:- artery/aorta:- vein:- lymphnode:0.05 peripheral blood:- spleen:- thymus:- bone marrow:- adipose:0.14 bone:- skin:-
reproductive muscular alimentary liver lung urinary endo/exo-crine
EST uterus:100.20 placenta:65.60 prostate:33.80 ovary:37.30 testis:164.40 heart:76.60 muscle:40.20 esophagus:- stomach:42.50 intestine:32.40 colon:17     liver/hepato:52.80        lung:156.40    bladder:- kidney:41.60 pituitary:- thyroid/parathyroid:- adrenal gland:- pancreas:44.50 breast:27.90 salivary:328.40
GeneChip uterus:5.02 placenta:4.83 prostate:5.04 ovary:4.95 testis:8.26 heart:5.27 muscle:5.22 esophagus:4.94 stomach:4.89 intestine:4.81 colon:4.90 liver/hepato:6.10 lung:5.05 bladder:- kidney:5.11 pituitary:5.30 thyroid/parathyroid:6.14 adrenal gland:5.02 pancreas:5.04 breast:4.97 salivary:5.22
CAGE uterus:0 placenta:0 prostate:0 ovary:0 testis:3.17 heart:0 muscle:0 esophagus:0 stomach:- intestine:0 colon:0     liver/hepato:0    lung:0 bladder:0 kidney:0 pituitary:0 thyroid/parathyroid:0 adrenal gland:- pancreas:0 breast:0 salivary:0
RNA-seq uterus:- placenta:- prostate:0.32 ovary:0.27 testis:4.82 heart:0.21 muscle:0 esophagus:- stomach:- intestine:- colon:0.23     liver/hepato:0.15        lung:0.18    bladder:- kidney:1.22 pituitary:- thyroid/parathyroid:0.66 adrenal gland:0.21 pancreas:- breast:0.09 salivary:-

Gene Information

IDs

Refseq ID NM_000197
Gene ID 3293
Unigene ID Hs.477003
Probe set ID 206985_at  [HG-U133_Plus_2]
Ensembl ID ENSG00000130948
GTEx ID ENSG00000130948

Orthologous Gene

Mouse[1]  NM_008291
Rat [0]  

Chromosomal Region

9q22.32  [98,997,588  -  99,064,434]

Gene Family (Interpro ID)

IPR002347  Glucose/ribitol dehydrogenase
IPR002198  Short-chain dehydrogenase/reductase SDR

Link to Pubmed  (Pubmed ID)

598011
2918056
6310248
8075637
8550739
8626842
9467575
9709959
9758445
11158067
12210481
12477932
14634838
15489334
15583024
15654505
16174723
17466011
17509588
18510611
19027726
19429456
19453261
19505920
19574343
19598235
20059664
20214802
20453000
20634197
20677014
20734064
22137341
22594312
23183177
23375913
23916922
23953348

Gene Ontology  (GO ID)

Biological Process

GO:0006702  androgen biosynthetic process
GO:0030539  male genitalia development
GO:0008202  steroid metabolic process

Cellular Component

GO:0005789  endoplasmic reticulum membrane
GO:0043231  intracellular membrane-bounded organelle

Molecular Function

GO:0047045  testosterone 17-beta-dehydrogenase (NADP+) activity